A Multi-Path Compensation Method for Ranging in Wearable Ultrasonic Sensor Networks for Human Gait Analysis.

Gait analysis in unrestrained environments can be done with a single wearable ultrasonic sensor node on the lower limb and four fixed anchor nodes. The accuracy demanded by such systems is very high. Chirp signals can provide better ranging and localization performance in ultrasonic systems. However, we cannot neglect the multi-path effect in typical indoor environments for ultrasonic signals. The multi-path components closer to the line of sight component cannot be identified during correlation reception which leads to errors in the estimated range and which in turn affects the localization and tracking performance. We propose a novel method to reduce the multi-path effect in ultrasonic sensor networks in typical indoor environments. A gait analysis system with one mobile node attached to the lower limb was designed to test the performance of the proposed system during an indoor treadmill walking experiment. An optical motion capture system was used as a benchmark for the experiments. The proposed method gave better tracking accuracy compared to conventional coherent receivers. The static measurements gave 2.45 mm standard deviation compared to 10.45 mm using the classical approach. The RMSE between the ultrasonic gait analysis system and the reference system improved from 28.70 mm to 22.28 mm. The gait analysis system gave good performance for extraction of spatial and temporal parameters.

A Doppler-Tolerant Ultrasonic Multiple Access Localization System for Human Gait Analysis.

Ranging based on ultrasonic sensors can be used for tracking wearable mobile nodes accurately for a long duration and can be a cost-effective method for human movement analysis in rehabilitation clinics. In this paper, we present a Doppler-tolerant ultrasonic multiple access localization system to analyze gait parameters in human subjects. We employ multiple access methods using linear chirp wave-forms and narrow-band piezoelectric transducers. A Doppler shift compensation Technique is also incorporated without compromising on the tracking accuracy. The system developed was used for tracking the trajectory of both lower limbs of five healthy adults during a treadmill walk. An optical motion capture system was used as the reference to compare the performance. The average Root Mean Square Error values between the 3D coordinates estimated from the proposed system and the reference system while tracking both lower limbs during treadmill walk experiment by 5 subjects were found to be 16.75, 14.68 and 20.20 mm respectively along X, Y and Z-directions. Errors in the estimation of spatial and temporal parameters from the proposed system were also quantified. These promising results show that narrowband ultrasonic sensors can be utilized to accurately track more than one mobile node for human gait analysis.

Lower Extremity Joint Angle Tracking with Wireless Ultrasonic Sensors during a Squat Exercise.

This paper presents an unrestrained measurement system based on a wearable wireless ultrasonic sensor network to track the lower extremity joint and trunk kinematics during a squat exercise with only one ultrasonic sensor attached to the trunk. The system consists of an ultrasound transmitter (mobile) and multiple receivers (anchors) whose positions are known. The proposed system measures the horizontal and vertical displacement, together with known joint constraints, to estimate joint flexion/extension angles using an inverse kinematic model based on the damped least-squares technique. The performance of the proposed ultrasonic measurement system was validated against a camera-based tracking system on eight healthy subjects performing a planar squat exercise. Joint angles estimated from the ultrasonic system showed a root mean square error (RMSE) of 2.85° ± 0.57° with the reference system. Statistical analysis indicated great agreements between these two systems with a Pearson's correlation coefficient (PCC) value larger than 0.99 for all joint angles' estimation. These results show that the proposed ultrasonic measurement system is useful for applications, such as rehabilitation and sports.

Estimation of spatial-temporal gait parameters using a low-cost ultrasonic motion analysis system.

In this paper, a low-cost motion analysis system using a wireless ultrasonic sensor network is proposed and investigated. A methodology has been developed to extract spatial-temporal gait parameters including stride length, stride duration, stride velocity, stride cadence, and stride symmetry from 3D foot displacements estimated by the combination of spherical positioning technique and unscented Kalman filter. The performance of this system is validated against a camera-based system in the laboratory with 10 healthy volunteers. Numerical results show the feasibility of the proposed system with average error of 2.7% for all the estimated gait parameters. The influence of walking speed on the measurement accuracy of proposed system is also evaluated. Statistical analysis demonstrates its capability of being used as a gait assessment tool for some medical applications.

Light intensity field enhancement (LIFE) induced localized edge abrasion of silica-coated silver nanoprisms.

Silver nanoprisms (AgNPrs) exhibit localized surface plasmon resonance (LSPR) in the near infrared (NIR) region of the electromagnetic spectrum. LSPR-driven electric field enhancement around AgNPr edges has been investigated in various studies. A coating of dielectric materials such as silica on the surface of the AgNPrs is employed to extend the application of these nanoparticles under biocompatible conditions and to increase the thermal stability. Upon interactions with optical excitation (pulsed laser excitation), the AgNPrs undergo light intensity field enhancement (LIFE) at the corners. In the cases of hybrid hetero-structures of AgNPrs with silica coatings (AgNPr@SiO2), LIFE leads to nano-structural deformations. In this study, we demonstrate that, depending on the intensity of the light excitation, the medium properties and the geometrical sharpness of the corners of the prisms, LIFE could induce localized damage or abrasion at the edges of the immediate dielectric contact, which in this case was the silica coating. A theoretical study was conducted to establish the influence of the finite radius of curvature (ROC) of the corners on the plasmonic interactions to generate LIFE during optical excitation. Experiments were performed on AgNPr@SiO2 using nanosecond pulsed laser excitation at 900 nm and electron microscopic analysis of the nanostructures revealed the localized edge abrasion of the silica at the prism corners. To further study the effect of the direct plasmonic excitation during LIFE, pulsed laser excitation on ultra-thin graphene oxide (GO) wrapped AgNPr@SiO2 (GO-AgNPr@SiO2) was conducted. Due to the GO wrapping and subsequent changes in light absorption, the extent of the LIFE at the corners diminishes, which leads to structural stability and preservation of the hetero-structure morphology.

Assessment of Foot Trajectory for Human Gait Phase Detection Using Wireless Ultrasonic Sensor Network.

This paper presents a new highly accurate gait phase detection system using wearable wireless ultrasonic sensors, which can be used in gait analysis or rehabilitation applications. The gait phase detection system uses the foot displacement information during walking to extract the following gait phases: heel-strike, heel-off, toe-off, and mid-swing. The displacement of foot-mounted ultrasonic sensor is obtained from several passive anchors placed at known locations by employing local spherical positioning technique, which is further enhanced by the combination of recursive Newton-Gauss method and Kalman Filter. The algorithm performance is examined by comparing with a commercial optical motion tracking system with ten healthy subjects and two foot injured subjects. Accurate estimates of gait cycle (with an error of -0.02 ±0.01 s), stance phase(with an error of 0.04±0.03 s), and swing phase (with an error of -0.05±0.03 s) compared to the reference system are obtained. We have also investigated the influence of walking velocities on the performance of the proposed gait phase detection algorithm. Statistical analysis shows that there is no significant difference between both systems during different walking speeds. Moreover, we have tested and discussed the possibility of the proposed system for clinical applications by analyzing the experimental results for both healthy and injured subjects. The experiments show that the estimated gait phases have the potential to become indicators for sports and rehabilitation engineering.

Ambulatory measurement of three-dimensional foot displacement during treadmill walking using wearable wireless ultrasonic sensor network.

Techniques that could be used to monitor human motion precisely are helpful in various applications such as rehabilitation, gait analysis, and athletic performance analysis. This paper focuses on the 3-D foot trajectory measurements based on a wearable wireless ultrasonic sensor network. The system consists of an ultrasonic transmitter (mobile) and several receivers (anchors) with fixed known positions. In order not to restrict the movement of subjects, a radio frequency (RF) module is used for wireless data transmission. The RF module also provides the synchronization clock between mobile and anchors. The proposed system measures the time-of-arrival (TOA) of the ultrasonic signal from mobile to anchors. Together with the knowledge of the anchor's position, the absolute distance that the signal travels can be computed. Then, the range information defines a circle centered at this anchor with radius equal to the measured distance, and the mobile resides within the intersections of several such circles. Based on the TOA-based tracking technique, the 3-D foot trajectories are validated against a camera-based motion capture system for ten healthy subjects walking on a treadmill at slow, normal, and fast speeds. The experimental results have shown that the ultrasonic system has sufficient accuracy of net root-mean-square error ( 4.2 cm) for 3-D displacement, especially for foot clearance with accuracy and standard deviation ( 0.62 ±7.48 mm) compared to the camera-based motion capture system. The small form factor and lightweight feature of the proposed system make it easy to use. Such a system is also much lower in cost compared to the camera-based tracking system.

Adaptive routing for dynamic on-body wireless sensor networks.

Energy is scarce in mobile computing devices including wearable and implantable devices in a wireless body area network. In this paper, an adaptive routing protocol is developed and analyzed which minimizes the energy cost per bit of information by using the channel information to choose the best strategy to route data. In this approach, the source node will switch between direct and relayed communication based on the quality of the link and will use the relay only if the channel quality is below a certain threshold. The mathematical model is then validated through simulations which shows that the adaptive routing strategy can improve energy efficiency significantly compared with existing methods.

A wearable wireless ultrasonic sensor network for human arm motion tracking.

This paper introduces a novel method for arm flexion/extension angles measurement using wireless ultrasonic sensor network. The approach uses unscented Kalman filter and D-H kinematical chain model to retrieve the joint angles. This method was experimentally validated by calculating the 2-dimensional wrist displacements from one mobile, placed on the point of subject's wrist, and four anchors. The performance of the proposed ultrasonic motion analysis system was bench-marked by commercial camera motion capture system. The experimental results demonstrate that a favorable performance of the proposed system in the estimation of upper limb motion. The proposed system is wireless, easy to wear, to use and much cheaper than current camera system. Thus, it has the potential to become a new and useful tool for routine clinical assessment of human motion.

Ambulatory measurement of foot kinematics using wearable ultrasonic sensors.

In this paper, an ultrasonic-based system for foot parameters measurement has been proposed and investigated. An extended Kalman filtering-based methodology has been developed to extract foot parameters including step length, stride length and cycle time from horizontal displacement during walking. The system comprises of one ultrasonic transmitter (mobile) and four ultrasonic receivers (anchors) with fixed known positions. A Radio Frequency (RF) module is used in our system not only to provide synchronization clock between the mobile and anchors, but also to transmit collected data wirelessly to reduce the wires used. To evaluate the performance of the proposed system, the 2-dimensional foot displacement and the foot parameters were measured and validated against the reference camera motion capture system. These experiment results demonstrate the capability of the proposed system being used as a gait analysis tool for rehabilitation and other medical applications.

A novel approach to joint flexion/extension angles measurement based on wearable UWB radios.

In this paper, a new method for measuring and monitoring human body joint angles, which uses wearable ultrawideband (UWB) transceivers mounted on body segments, is proposed and investigated. The model is based on providing a high ranging accuracy (intersensor distance) between a pair of transceivers placed on the adjacent segments of the joint center of rotation. The measured distance is then used to compute the joint angles based on the law of cosines. The performance of the method was compared with a flexible goniometer by simultaneously measuring joint flexion-extension angles at different angular velocities, ranging between 8 and 90(°) /s. The measurement errors were evaluated by the average differences between two sets of data (ranging from 0.8(°) for slow movement to 2.8(°) for fast movement), by standard deviation (ranging from 1.2(°) to 4.2(°) for various movement speeds) and by the Pearson correlation coefficient (greater than 0.99) which demonstrates the very good performance of the UWB-based approach. The experimental results have shown that the system has sufficient accuracy for clinical applications, such as rehabilitation.

Using wearable UWB radios to measure foot clearance during walking.

Foot clearance above ground is a key factor for a better understanding of the complicated relationship between falls and gait. This paper proposes a wearable system using UWB transceivers to monitor the vertical heel/toe clearance during walking. First, a pair of very small and light antennas is placed on a point approximating to the heel/toe of the foot, acting as a transmitter and receiver. Then, the reflected signal from ground is captured and propagation delay is detected using noise suppressed Modified-Phase-Only-Correlator (MPOC). The performance of the UWB-based system was compared with an ultrasound system for stationary movements. The experimental results show that an overall mean difference between these two systems is about 0.634mm with correlation coefficient value of 0.9604. The UWB-based system is then used to measure foot clearance during walking which shows promising results for gait events detection.

Measurement of knee flexion/extension angle using wearable UWB radios.

This paper proposes a wearable system using UWB transceivers to measure the knee flexion/extension angle parameter, who is known to be of clinical importance. First, a pair of very small and light antennas is placed on the adjacent segments of knee joint. Then, the range data between these two antennas is acquired using Time of Arrival (TOA) estimator. We further use the measured distance to compute the flexion/extension angle using the law of cosines. The performance of the method was compared with a flexible goniometer by simultaneously measuring knee flexion-extension angle. The experimental results show that the system has reasonable performance and has sufficient accuracy for clinical applications.

Effect of lesion morphology on microwave signature in 2-D ultra-wideband breast imaging.

This paper studies the possibility of distinguishing between benign and malignant masses by exploiting the morphology-dependent temporal and spectral characteristics of their microwave backscatter response in ultra-wideband breast cancer detection. The spiculated border profiles of 2-D breast masses are generated by modifying the baseline elliptical rings based upon the irregularity of their peripheries. Furthermore, the single- and multilayer lesion models are used to characterize a distinct mass region followed by a sharp transition to background, and a blurred mass border exhibiting a gradual transition to background, respectively. Subsequently, the complex natural resonances (CNRs) of the backscatter microwave signature can be derived from the late-time target response and reveal diagnostically useful information. The fractional sequence CLEAN algorithm is proposed to estimate the lesions' delay intervals and identify the late-time responses. Finally, it is shown through numerical examples that the locations of dominant CNRs are dependent on the lesion morphologies, where 2-D computational breast phantoms with single and multiple lesions are investigated. The analysis is of potential use for discrimination between benign and malignant lesions, where the former usually possesses a better-defined, more compact shape as opposed to the latter.

UWB microwave breast cancer detection: generalized models and performance prediction.

This paper presents a generic framework for the modeling of ultra-wideband (UWB) signal propagation in human breast, which facilitates system-level simulations and provides performance prediction. The clutter associated with the breast tissue heterogeneity is modeled through several key parameters depending on the tissue compositions. Subsequently, important channel properties such as the backscatter energy and the probability density function of time-of-arrival are derived. The modified Hermite polynomials, which fit well into the real pulse shapes, are then used to model the UWB signals. Armed with the channel/signal model preliminaries, three metrics are proposed, namely, the mean clutter response, the clean tumor response, and the worst-case clutter response. The generalized model provides a parsimonious way to study the effects of tissue structures, pulse templates, and array setup on the performance of a specified UWB imaging system. Numerical examples are used to demonstrate the usefulness of the proposed approach.

Non-invasive respiration rate estimation using ultra-wideband distributed cognitive radar system.

It has been shown that remote monitoring of pulmonary activity can be achieved using ultra-wideband (UWB) systems, which shows promise in home healthcare, rescue, and security applications. In this paper, a geometry-based statistical channel model is developed for simulating the reception of UWB signals in the indoor propagation environment. This model enables replication of time-varying multipath profiles due to the displacement of a human chest. Subsequently, a UWB distributed cognitive radar system (UWB-DCRS) is developed for the robust detection of chest cavity motion and the accurate estimation of respiration rate. The analytical framework can serve as a basis in the planning and evaluation of future measurement programs.