[Immunobiological properties of bacteria].

Opsonins found on the surface of microbial cells in vivo and ex vivo are characterized. The possibility of their visualization by immune electron and fluorescent microscopy has been demonstrated. Opsonins are shown to play a role in immune-mediated adhesion of bacteria to phagocytes and erythrocytes and formation of virus-bacterium associations. Staphylococci, Streptococci, and Propionibacteria appear to actively adsorb blood proteins on their cell surface giving rise to well-apparent capsular structures tentatively called immunoglobulin coatings. Pathogen (microorganism)-associated molecular patterns of gram-positive and gram-negative bacteria show different degree of interaction with soluble proteins that in turn promote their adhesion to blood corpuscles. The role of erythrocytes in transportation and elimination of immune complexes bound to their membrane receptors is discussed.

[Human microecology studies at Department of Microbiology with Virology and Immunology, I.M. Sechenov Moscow Medical Academy]. / Issledovanie po mikroékologii cheloveka na kafedre mikrobiologii s virusologiei i immunologiei.

Studies of human microflora in health and disease and during exposure to professional and ecological factors is a traditional problem solved for many years by staff members of Department of Microbiology with Virology and Immunology, I. M. Setchenov Moscow Medical Academy. The purpose of research is to develop methods and means for diagnosis and prevention of human microbiocenosis disorders. Fundamental and applied research in cooperation with prophylactic and clinical institutions and departments yielded data contributing to solution of many pressing problems in prevention and diagnosis of infectious diseases.

[Skin microbiocenosis in patient with chronic dermatoses]. / Mikrotsenoz kozhi bol'nykh khronicheskimi dermatozami.

The skin microflora of patients with chronic dermatoses (atopic dermatitis and psoriasis) have been studied by the original "Bactotests" method. The data thus obtained indicate that the clinical picture of the disease is related to the severity of skin dysbacteriosis. The electron-microscopic study of 2 staphylococcal strains isolated from patients has revealed the presence of the immunoglobulin cover (capsule-like outer sheath consisting of immunoglobulins and other humoral protective factors) on the cell wall of these bacteria.