RESUMEN
Non-Hodgkin's lymphoma (NHL) incidence rates have increased more than 50% over the past 15 years, making it the sixth leading cause of death from cancer in the United States and the fourth most significant malignancy in terms of economic impact. Comparable trends are noted worldwide. Improved diagnostic techniques have resulted in reclassifying some tumors that in the past would have been classified as Hodgkin's disease. In this article, the latest diagnostic, prognostic, and treatment options for NHL are reviewed and a cross-reference chart for these evolving class systems provided.
Asunto(s)
Linfoma no Hodgkin , Análisis Actuarial , Humanos , Incidencia , Linfoma no Hodgkin/economía , Linfoma no Hodgkin/epidemiología , Linfoma no Hodgkin/etiología , Linfoma no Hodgkin/patología , Linfoma no Hodgkin/terapia , Estadificación de Neoplasias , Pronóstico , Factores de Riesgo , Programa de VERF , Estados Unidos/epidemiologíaRESUMEN
Although nasopharyngeal carcinoma (NPC) is a rare cancer in the United States, it is a leading cause of death in other countries. Dr Titcomb reviews several facts about NPC that can be helpful to underwriters as they encounter this tumor in applicants who reside in, or who are a native of, an area of high incidence.
Asunto(s)
Neoplasias Nasofaríngeas , Neoplasias Nasofaríngeas/epidemiología , Asia/epidemiología , Femenino , Humanos , Incidencia , Masculino , Neoplasias Nasofaríngeas/diagnóstico , Neoplasias Nasofaríngeas/terapiaRESUMEN
Evaluation of applicants for life insurance who have elevations of their liver function tests or an increased probability of alcohol abuse has always been difficult for underwriters. This paper reports the results of an intercompany study in which the pooled mortality experience of a group of insureds with evidence of alcohol abuse, an adverse driving record or elevations of the liver transaminases or gamma-glutamyl transferase is summarized.
Asunto(s)
Alcoholismo , Hepatopatías , Adulto , Anciano , Alcoholismo/enzimología , Alcoholismo/mortalidad , Aspartato Aminotransferasas/sangre , Conducción de Automóvil , Biomarcadores/sangre , Femenino , Humanos , Seguro de Vida , Hepatopatías/enzimología , Hepatopatías/mortalidad , Masculino , Persona de Mediana Edad , Factores Sexuales , Encuestas y Cuestionarios , gamma-Glutamiltransferasa/sangreRESUMEN
Cancer is the second leading cause of death in women of child-bearing age. Carcinoma of the breast, an estimated 135,000 new cases of which were diagnosed in the USA in 1988, is the most common cancer in American women. Malignant disease complicates 1 in 1,000 pregnancies, with breast cancer diagnosed in but 1 of 3,500. Conversely, only 1% to 3% of breast cancers are associated with pregnancy and the period of lactation (the latter defined as the period of 1 year postpartum). In his review of world medical literature from 1850 to 1950, White found in a total of 45,881 women with breast cancer, only 1,296 cases (2.8%) occurring in pregnancy. Indeed, the bulk of breast cancer is diagnosed in post-menopausal women. Of 31,594 cases reported to the Cancer Registry of Norway from 1955 to 1980, women aged 50 and older comprised 73%, whereas women under the age of 35, less than 2% of the total. Breast cancer becomes significant, however, among the subgroup of women of childbearing age. In the same series of 31,592 women, 10% of those less than 35 years of age were pregnant at the time of diagnosis and an additional 15% had given birth within the year prior to diagnosis.