Evaluation of the relationship between the Mediterranean diet adherence and sleep quality in adults.

PURPOSE: To investigate the association between Mediterranean diet adherence (MDA) and sleep quality in adults. METHODS: This cross-sectional research was conducted among adults aged 19-64 years in Ankara, Türkiye. Data on demographics, education, lifestyle, and physical activity habits were collected. Mediterranean diet adherence was assessed with the Mediterranean Diet Adherence Screener (MEDAS). Healthy eating attitudes were evaluated with the Attitude Scale for Healthy Nutrition (ASHN). Sleep quality was measured with the Pittsburgh Sleep Quality Index (PSQI). Data were gathered using an online format. RESULTS: Among 1031 participants enrolled (74% women), mean age was 28.6 ± 8.3 years. Median age increased with MDA (p = 0.001). As individuals' MDA increased, ASHN total and subgroup scores also increased significantly (p < 0.001). The total sleep duration of the participants with low MDA was significantly lower than the other groups (p = 0.003). Pittsburgh Sleep Quality Index score and MEDAS (ß = - 0.222, p < 0.001), ASHN (ß = - 0.043, p < 0.001) and ASHN subgroups (ß = (- 0.086) - (- 0.031)) were found to have a weakly signficant negative relation. CONCLUSIONS: The findings suggest that healthy eating attitudes and nutritional behavior in accordance with the Mediterranean diet are associated with sleep quality.

Effect of emotional eating and social media on nutritional behavior and obesity in university students who were receiving distance education due to the COVID-19 pandemic.

Aim: This study aimed to evaluate the effects of emotional eating and social media on nutritional behavior and obesity in university students receiving distance education during the pandemic. Subject and methods: This cross-sectional study was performed with 1000 undergraduate students who were receiving distance education due to COVID-19 in Türkiye. Data were collected using an online questionnaire that included demographic information, height, body weight, eating habits, the Scale of Effects of Social Media on Eating Behavior (SESMEB), and the Emotional Eating Scale (EES). A p value less than 0.05 was considered as statistically significant for statistical tests. Results: During the distance education period, more than half of both male and female students (61.7%; 58.2%) changed their meal pattern, 31.7% of them started to consume their main meals more regularly, and 31.2% of them began to skip their main meals. Of the participants, 52.6% spent more than 2 hours a day on social media. The female students who spend more than 2 hours a day on social media have higher SESMEB and EES scores than those who spend 2 hours or less a day (p < 0.01). The score SESMEB is positively weakly correlated with body mass index (BMI) (rho 0.132, p < 0.01) and positively moderately associated with the EES score (rho 0.334, p < 0.01). The interaction between the SESMEB and EES scores increases the risk of overweight/obesity (odds ratio (OR) 1.002, p = 0.009). Conclusion: For the students who received distance education, social media affects eating behavior, BMI, and emotional eating. Additionally, these effects may increase the risk of overweight/obesity.

Effect of saccharin, a non-nutritive sweeteners, on insulin and blood glucose levels in healthy young men: A crossover trial.

BACKGROUND AND AIMS: Artificial sweeteners used instead of sugar were considered as the best alternatives that have no endocrine effects. However, it has recently been suggested that artificial sweeteners may cause impaired metabolic parameters. The hypothesis of the study was there is an association between acute saccharin consumption and both glycemia and insulin response in young healthy adult men. METHODS: 9 healthy adult males were included in this study. This study randomly provided participants with preloads as (a)300 ml of water, or 300 ml of water sweetened with (b)75 g of sucrose, (c)240 mg of saccharine (adjusted to the sweetness of 75 g of sucrose) 1 h before a standard breakfast. RESULTS: Compared to mean blood glucose and serum insulin after test drinks consumption, there was only one difference between sucrose and saccharin trials in the 15th minute (117.0 ± 18.70, 95.4 ± 5.64 mg/dl respectively, p < 0.05). At the 60th minute, insulin secretion (0.80 ± 0.27 pg/dl) after the sucrose trial was found significantly higher than the saccharin trial (0.53 ± 0.09 pg/dl) and water (0.49 ± 0.06 pg/dl) (p < 0.05). Although at all intervals (except 90th minute), the mean insulin is higher after the saccharin trial compared to the water trial, these were non-statistically significant differences (p > 0.05). CONCLUSIONS: Consequently, it was determined that saccharin had no glycemic effect. However, for the effect on serum insulin to be clarified, the long-term effects should be investigated.

Characterization of the self-assembly and size dependent structural properties of dietary mixed micelles by molecular dynamics simulations.

The bile salts and phospholipids are secreted by the gallbladder to form dietary mixed micelles in which the solvation of poorly absorbed lipophilic drugs and nutraceuticals take place. A comprehensive understanding of the micellization and structure of the mixed micelles are crucial to design effective delivery systems for such substances. In this study, the evolution of the dietary mixed micelle formation under physiologically relevant concentrations and the dependence of structural properties on micelle size were investigated through coarse-grained molecular dynamics simulations. The MARTINI force field was used to model cholate and POPC as the representative bile salt and phospholipid, respectively. The micellization behavior was similar under both fasted and fed state concentrations. Total lipids concentration and the micelle size did not affect the internal structure of the micelles. All the micelles were slightly ellipsoidal in shape independent of their size. The extent of deviation from spherical geometry was found to depend on the micellar POPC/cholate ratio. We also found that the surface and core packing density of the micelles increased with micelle size. The former resulted in more perpendicular alignments of cholates with respect to the surface, while the latter resulted in an improved alignment of POPC tails with the radial direction and more uniform core density.