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Eur Rev Med Pharmacol Sci ; 26(17): 6114-6120, 2022 09.
Artículo en Inglés | MEDLINE | ID: mdl-36111913

RESUMEN

OBJECTIVE: The incidence of thyroid cancer and metabolic syndrome has been increasing at the same rate over the past few decades. We hypothesized that there would be a direct relationship between thyroid papillary cancer and triglyceride/glucose index (TyG). PATIENTS AND METHODS: A total of 382 operated patients were divided into two groups: patients operated on for papillary thyroid cancer and for non-malignant reasons. Each patient's age, gender, operation times, presence of neck dissection, serum thyroid-stimulating hormone (TSH), free triiodothyronine (FT3) and free thyroxine (FT4), fasting blood glucose and triglyceride levels were scanned retrospectively from the archive system. RESULTS: TyG index was statistically higher in the malignant group. Receiver operating characteristic (ROC) curves obtained for TyG levels at the time of diagnosis of thyroid papillary cancer were AUC: 0.608. The threshold value for TyG was 6,252. The sensitivity of this value was 62.8% and the specificity was 49.2%. CONCLUSIONS: In this study, we investigated the predictive effect of the TyG index in differentiating thyroid papillary carcinoma from non-malignant thyroid lesions. We concluded that the TgY index can be used to identify people at high risk of thyroid papillary cancer and to plan treatment.


Asunto(s)
Glucemia , Resistencia a la Insulina , Cáncer Papilar Tiroideo , Triglicéridos , Glucemia/química , Glucemia/metabolismo , Glucosa/química , Glucosa/metabolismo , Humanos , Resistencia a la Insulina/fisiología , Estudios Retrospectivos , Cáncer Papilar Tiroideo/sangre , Cáncer Papilar Tiroideo/metabolismo , Neoplasias de la Tiroides/química , Neoplasias de la Tiroides/metabolismo , Tirotropina , Tiroxina , Triglicéridos/química , Triglicéridos/metabolismo , Triyodotironina
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