Detalles de la búsqueda
1.
High-Dose Isoniazid Lacks EARLY Bactericidal Activity Against Isoniazid-resistant Tuberculosis Mediated by katG Mutations: A Randomized, Phase 2 Clinical Trial.
Am J Respir Crit Care Med
; 2024 Apr 02.
Artículo
Inglés
| MEDLINE | ID: mdl-38564365
2.
Early Bactericidal Activity of Meropenem plus Clavulanate (with or without Rifampin) for Tuberculosis: The COMRADE Randomized, Phase 2A Clinical Trial.
Am J Respir Crit Care Med
; 205(10): 1228-1235, 2022 05 15.
Artículo
Inglés
| MEDLINE | ID: mdl-35258443
3.
Pharmacokinetics of bedaquiline in cerebrospinal fluid (CSF) in patients with pulmonary tuberculosis (TB).
J Antimicrob Chemother
; 77(6): 1720-1724, 2022 05 29.
Artículo
Inglés
| MEDLINE | ID: mdl-35257182
4.
Resistance to Mycobacterium tuberculosis Infection Among Household Contacts: A Multinational Study.
Clin Infect Dis
; 73(6): 1037-1045, 2021 09 15.
Artículo
Inglés
| MEDLINE | ID: mdl-33772550
5.
Drug susceptibility patterns of Mycobacterium tuberculosis from adults with multidrug-resistant tuberculosis and implications for a household contact preventive therapy trial.
BMC Infect Dis
; 21(1): 205, 2021 Feb 24.
Artículo
Inglés
| MEDLINE | ID: mdl-33627075
6.
Cerebrospinal Fluid and Tuberculous Meningitis.
Clin Infect Dis
; 77(1): 158, 2023 07 05.
Artículo
Inglés
| MEDLINE | ID: mdl-36987607
7.
Resistance-Conferring Mycobacterial Mutations and Quantification of Early Bactericidal Activity.
Am J Respir Crit Care Med
; 203(5): 635-637, 2021 03 01.
Artículo
Inglés
| MEDLINE | ID: mdl-33080154
8.
Power to identify exposure-response relationships in phase IIa pulmonary tuberculosis trials with multi-dimensional bacterial load modeling.
CPT Pharmacometrics Syst Pharmacol
; 13(3): 374-385, 2024 03.
Artículo
Inglés
| MEDLINE | ID: mdl-38102814
9.
Risk Factors for COVID-19 and Respiratory Tract Infections during the Coronavirus Pandemic.
Vaccines (Basel)
; 12(3)2024 Mar 19.
Artículo
Inglés
| MEDLINE | ID: mdl-38543963
10.
A first-in-class leucyl-tRNA synthetase inhibitor, ganfeborole, for rifampicin-susceptible tuberculosis: a phase 2a open-label, randomized trial.
Nat Med
; 30(3): 896-904, 2024 Mar.
Artículo
Inglés
| MEDLINE | ID: mdl-38365949
11.
Bedaquiline-pretomanid-moxifloxacin-pyrazinamide for drug-sensitive and drug-resistant pulmonary tuberculosis treatment: a phase 2c, open-label, multicentre, partially randomised controlled trial.
Lancet Infect Dis
; 2024 May 17.
Artículo
Inglés
| MEDLINE | ID: mdl-38768617
12.
Liquid chromatography-tandem mass spectrometry analysis of delamanid and its metabolite in human cerebrospinal fluid using protein precipitation and on-line solid-phase extraction.
J Pharm Biomed Anal
; 227: 115281, 2023 Apr 01.
Artículo
Inglés
| MEDLINE | ID: mdl-36739721
13.
Seasonal influence on respiratory tract infection severity including COVID-19 quantified through Markov Chain modeling.
CPT Pharmacometrics Syst Pharmacol
; 12(9): 1250-1261, 2023 09.
Artículo
Inglés
| MEDLINE | ID: mdl-37401774
14.
Standards for model-based early bactericidal activity analysis and sample size determination in tuberculosis drug development.
Front Pharmacol
; 14: 1150243, 2023.
Artículo
Inglés
| MEDLINE | ID: mdl-37124198
15.
Reproducibility in pharmacometrics applied in a phase III trial of BCG-vaccination for COVID-19.
Sci Rep
; 13(1): 16292, 2023 09 28.
Artículo
Inglés
| MEDLINE | ID: mdl-37770596
16.
Transrenal Mycobacterium tuberculosis DNA in pulmonary tuberculosis patients during the first 14 days of treatment.
Microbiol Spectr
; 11(6): e0234823, 2023 Dec 12.
Artículo
Inglés
| MEDLINE | ID: mdl-37882572
17.
Early bactericidal activity studies for pulmonary tuberculosis: A systematic review of methodological aspects.
Int J Antimicrob Agents
; 61(5): 106775, 2023 May.
Artículo
Inglés
| MEDLINE | ID: mdl-36893811
18.
Assessing Prolongation of the Corrected QT Interval with Bedaquiline and Delamanid Coadministration to Predict the Cardiac Safety of Simplified Dosing Regimens.
Clin Pharmacol Ther
; 112(4): 873-881, 2022 10.
Artículo
Inglés
| MEDLINE | ID: mdl-35687528
19.
Population Pharmacokinetics of Delamanid and its Main Metabolite DM-6705 in Drug-Resistant Tuberculosis Patients Receiving Delamanid Alone or Coadministered with Bedaquiline.
Clin Pharmacokinet
; 61(8): 1177-1185, 2022 08.
Artículo
Inglés
| MEDLINE | ID: mdl-35668346
20.
Safety and efficacy of BCG re-vaccination in relation to COVID-19 morbidity in healthcare workers: A double-blind, randomised, controlled, phase 3 trial.
EClinicalMedicine
; 48: 101414, 2022 Jun.
Artículo
Inglés
| MEDLINE | ID: mdl-35582122