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1.
Geohealth ; 8(3): e2023GH000991, 2024 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-38487553

RESUMEN

Wildfires are increasing in frequency and intensity, with significant consequences that impact human health. A scoping review was conducted to: (a) understand wildfire-related health effects, (b) identify and describe environmental exposure and health outcome data sources used to research the impacts of wildfire exposures on health, and (c) identify gaps and opportunities to leverage exposure and health data to advance research. A literature search was conducted in PubMed and a sample of 83 articles met inclusion criteria. A majority of studies focused on respiratory and cardiovascular outcomes. Hospital administrative data was the most common health data source, followed by government data sources and health surveys. Wildfire smoke, specifically fine particulate matter (PM2.5), was the most common exposure measure and was predominantly estimated from monitoring networks and satellite data. Health data were not available in real-time, and they lacked spatial and temporal coverage to study health outcomes with longer latency periods. Exposure data were often available in real-time and provided better temporal and spatial coverage but did not capture the complex mixture of hazardous wildfire smoke pollutants nor exposures associated with non-air pathways such as soil, household dust, food, and water. This scoping review of the specific health and exposure data sources used to underpin these studies provides a framework for the research community to understand: (a) the use and value of various environmental and health data sources, and (b) the opportunities for improving data collection, integration, and accessibility to help inform our understanding of wildfires and other environmental exposures.

2.
Insect Mol Biol ; 19 Suppl 2: 259-72, 2010 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-20482656

RESUMEN

Aphids are the primary vectors of plant viruses. Transmission can occur via attachment to the cuticle lining of the insect (non-circulative transmission) or after internalization in the insect cells with or without replication (circulative transmission). In this paper, we have focused on the circulative and non-propagative mode during which virions enter the cell following receptor-mediated endocytosis, are transported across the cell in vesicles and released by exocytosis without replicating. The correct uptake, transport and delivery of the vesicles cargo relies on the participation of proteins from different families which have been identified in the Acyrthosiphon pisum genome. Assemblage of this annotated dataset provides a useful basis to improve our understanding of the molecules and mechanisms involved in virus transmission by A. pisum and other aphid species.


Asunto(s)
Áfidos/genética , Áfidos/virología , Genoma de los Insectos , Virus de Plantas/patogenicidad , Actinas/genética , Actinas/fisiología , Animales , Áfidos/patogenicidad , Áfidos/fisiología , Clatrina/genética , Clatrina/fisiología , Vesículas Cubiertas por Clatrina/genética , Vesículas Cubiertas por Clatrina/fisiología , Vesículas Cubiertas por Clatrina/virología , Dinaminas/genética , Dinaminas/fisiología , Endocitosis/genética , Endocitosis/fisiología , Exocitosis/genética , Exocitosis/fisiología , Proteínas de Insectos/genética , Proteínas de Insectos/fisiología , Insectos Vectores/virología , Luteoviridae/patogenicidad , Pisum sativum/parasitología , Pisum sativum/virología , Filogenia , Enfermedades de las Plantas/parasitología , Enfermedades de las Plantas/virología , Proteínas SNARE/genética , Proteínas SNARE/fisiología , Sinaptotagminas/genética , Sinaptotagminas/fisiología , Proteínas de Unión al GTP rab/genética , Proteínas de Unión al GTP rab/fisiología
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