[The cardiac microcirculatory bed based on data from the scanning electron microscopy of corrosion preparations]. / Mikrotsirkuliatornoe ruslo serdtsa po dannym skaniruiushchei élektronnoi mikroskopii korrozionnykh preparatov.

The method of scanning electron microscopy of cast preparations was used to study the volumetric interrelations of hemo- and lymph microcirculation bed links as well as specific features of the relief of the wall of the heart vessels in question. The lymphangions were confirmed to be rightfully considered as a morphological unit of the lymph microcirculation bed. The valve-shaped impressions and folds of the relief of a cast of lymph capillaries and postcapillaries were found which shows the ability of the lymph postcapillaries to maintain a one-direction flow of lymph and to change the lumen width for different amounts of the flowing lymph.

[Lymphatic bed of the heart and the nucleic acid content of the cardiomyocytes in alcohol poisoning]. / Limfaticheskoe ruslo serdtsa i soderzhanie nukleinovykh kislot kardiomiotsitov pri otravlenii alkogolem.

The lymphatic channel of the heart in alcohol poisoning and the content of nucleic acids in the cytoplasm and nuclei of cardiomyocytes were studied. Four forms of lymphatic capillaries, postcapillaries and lymphatic vessels were found: functioning, "dystrophized", sclerosing, and regenerating. Disorders of interfragment connections interfering with the lymph flow were observed. A decrease in the content of nucleic acids in the cytoplasm and nuclei of cardiomyocytes in alcohol poisoning was established.

[Transformation of the kidney lymphatic system in clinical pathology]. / Transformatsiia limfaticheskoi sistemy pochek v klinicheskoi patologii.

The nature of transformations in the renal lymphatic system in the clinical pathology of the kidneys, mainly in the final stage of chronic glomerulonephritis, hypertension, atherosclerosis, hydronephrotic transformation (45 autopsy kidneys) is demonstrated. The controls consisted of kidneys from patients dying with non-renal pathology (12 organs). In the final stages of the above diseases progressive reduction of the intraorgan lymphatic capillaries and vessels with simultaneous marked vascularization of the fibrous renal capsule due to an increase in the amount of lymphatic capillaries (their growth) and formation of new abducting lymph stems, numerous anastomoses between them, as well as distention in the vessel lumens and the development of varicosis of the wall. These morphological changes indicate high plastic properties of the lymphatic system and its role in the retention of the renal function in developing "local" lymph congestions in the organ because of outgrowth of the connective tissue. On the other hand, they are universal and reflect the time course of the progress.

[Cerebral vascular changes in severe cranio-cerebral trauma according to angiographic findings]. / Ob izmeneniiakh sosudov golovnogo mazga pri tiazheloi cherepno-mozgovoi travme po dannym angiografii

Modern radiocontrast methods of examination of the vascular system permit to reveal both morphological and functional alterations in the vascular architectonics. Angiographic studies were undertaken in 49 patients with severe craniocerebral injuries. The analysis of the angiogrammes revealed distinct changes in the number, position, shape and lumen of the cerebral vassels depending on the injury focus or brain compression.

[Primary controlled endolymphatic antibiotic therapy in traumatology and orthopedics]. / Priamaia upravlennaia éndolimfaticheskaia antibiotikoterapiia v travmatologii i ortopedii.

The work analyses 55 cases of traumatic osteomyelitis of the leg bones, open fractures of the leg bones, and medial fractures of the femoral neck. Patients with medial fractures of the neck of the femur were treated by endoprosthesis after Mur-Kaplan. Endolymphatic antibiotic therapy was included in the complex of therapeutic measures in each group of patients. This method allowed suppuration of the postoperative wounds to be avoided and promoted in this manner rehabilitation of the patients.

[Prophylaxis of purulent complications in operations on large joints by endolymphatic infusion of drugs]. / Profilaktika gnoinykh osloznenii pri operatsiiakh na krupnykh sustavakh s pomoshch'iu éndolimfaticheskogo vvedeniia lekarstvennykh veshchestv.

2 groups of patients operated on knee joints for traumatic injuries were examined. In the study group endolymphatic drug therapy was carried out in postoperative period, in control group of patients conventional way of intramuscular administration of preparations was used. During the treatment, plasmatic cells, macrophages and tissue basophiles in synovial liquor were studied as well as synthesis of nucleic acids (DNA and RNA) in plasmatic cells. It was shown that immune homeostasis of synovial liquor in postoperative period normalized faster in endolymphatic administration. The studies of tissue basophiles have shown that inflammatory process in the knee joint is completed faster when endolymphatic route of drug administration was used. Clinical results evidence of higher effectiveness of endolymphatic therapy in comparison with conventional method of treatment in postoperative period. In the former case the inflammatory process was completed by the 5th day, in the latter--by the 7th-9th day. The endolymphatic therapy in all the patients resulted in healing of operation wounds by primary intention. In the group of patients treated by standard methods, suppuration of the wound was detected in 6 from 27 patients and postoperative synovitis in 7-9 days was observed in 6 patients.

[Pathomorphological changes and the level of intestinal resection in acute occlusion of the mesenteric vessels]. / Patomorfologicheskie izmeneniia i uroven' rezektsii kishechnika pri ostroi &okkliuzii bryzheechnykh sosudov.

The analysis of 239 case histories and of 229 autopsy recores of patients died from this disease in set forth in the article. The ratio of mesenteric thrombosis and embolism constituted 2.78% of all the autopsies. The occlusion of the superior mesenteric artery was found in 76.0% of all the autopsies, of the mesenteric veins--in 14.7%, of the inferior mesenteric artery--in 4.2%, of both superior and inferior mesenteric arteries--in 4.2% and of the celiac and superior mesenteric arteries--in 0.83%.

[Experience with the experimental autograft of a skin-fascia flap with simultaneous restoration of the blood circulation in the graft]. / Oyt éksperimental'noi autotransplantatsii kozhno-fastsial'nogo loskuta s odnomomentnym vosstanovleniem krovoobrashcheniia v transplantate.

The use of the microsurgery allows to carry out the autotransplantation of the skin-fascial graft. Optic magnification, special instruments and suture material are necessary for the formation of anastomoses of the small diameter arteries and veins. The autotransplantation of skin-fascial grafts permits to correct extensive defects of the skin and underlying tissues. A thorough formation of vascular anastomoses and an adequate pharmacotherapy are of great importance.

[Endolymphatic antibiotic administration in the combined treatment of peritonitis]. / Endolimfaticheskoe vvedenie antibiotikov v kompleksnom lechenii peritonita.

The endolymphatic method of infusion of antibiotics was used in 165 patients with acute inflammatory diseases of organs of the abdominal cavity, 84,8% of them recovered. A single endolymphatic infusion of a usual dose of the antibiotic makes a very high concentration of the drug in the lymphatic system and maintains a therapeutic concentration of the antibiotic in the lymph during a day. In the lymphatic nodes it retains for more than 2 weeks. The methods reduces acute inflammatory processes, makes the temperature and blood leukocytes normal and improves the general state of the patients resulting in their quicker recovery. The endolymphatic therapy with antibiotics is in good agreement with surgical and other conservative methods of treatment.