Detalles de la búsqueda
1.
Small molecule MarR modulators potentiate metronidazole antibiotic activity in aerobic E. coli by inducing activation by the nitroreductase NfsA.
J Biol Chem
; : 107431, 2024 May 31.
Artículo
Inglés
| MEDLINE | ID: mdl-38825006
2.
Crystal structure of the Mycobacterium tuberculosis VirS regulator reveals its interaction with the lead compound SMARt751.
J Struct Biol
; 216(2): 108090, 2024 Jun.
Artículo
Inglés
| MEDLINE | ID: mdl-38548139
3.
Regioselective and Stereoselective Synthesis of Parthenolide Analogs by Acyl Nitroso-Ene Reaction and Their Biological Evaluation against Mycobacterium tuberculosis.
Int J Mol Sci
; 24(24)2023 Dec 12.
Artículo
Inglés
| MEDLINE | ID: mdl-38139224
4.
Rubrolone production by Dactylosporangium vinaceum: biosynthesis, modulation and possible biological function.
Appl Microbiol Biotechnol
; 105(13): 5541-5551, 2021 Jul.
Artículo
Inglés
| MEDLINE | ID: mdl-34189614
5.
Molecular Design in Practice: A Review of Selected Projects in a French Research Institute That Illustrates the Link between Chemical Biology and Medicinal Chemistry.
Molecules
; 26(19)2021 Oct 08.
Artículo
Inglés
| MEDLINE | ID: mdl-34641626
6.
Evaluation of critical parameters in the hollow-fibre system for tuberculosis: A case study of moxifloxacin.
Br J Clin Pharmacol
; 2024 Apr 17.
Artículo
Inglés
| MEDLINE | ID: mdl-38632083
7.
A novel codrug made of the combination of ethionamide and its potentiating booster: synthesis, self-assembly into nanoparticles and antimycobacterial evaluation.
Org Biomol Chem
; 17(20): 5129-5137, 2019 05 28.
Artículo
Inglés
| MEDLINE | ID: mdl-31073555
8.
Structural analysis of the interaction between spiroisoxazoline SMARt-420 and the Mycobacterium tuberculosis repressor EthR2.
Biochem Biophys Res Commun
; 487(2): 403-408, 2017 05 27.
Artículo
Inglés
| MEDLINE | ID: mdl-28416386
9.
New active leads for tuberculosis booster drugs by structure-based drug discovery.
Org Biomol Chem
; 15(48): 10245-10255, 2017 Dec 13.
Artículo
Inglés
| MEDLINE | ID: mdl-29182187
10.
Unconventional surface plasmon resonance signals reveal quantitative inhibition of transcriptional repressor EthR by synthetic ligands.
Anal Biochem
; 452: 54-66, 2014 May 01.
Artículo
Inglés
| MEDLINE | ID: mdl-24561027
11.
Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands.
Nucleic Acids Res
; 40(7): 3018-30, 2012 Apr.
Artículo
Inglés
| MEDLINE | ID: mdl-22156370
12.
Pyridylpiperazine efflux pump inhibitor boosts in vivo antibiotic efficacy against K. pneumoniae.
EMBO Mol Med
; 16(1): 93-111, 2024 Jan.
Artículo
Inglés
| MEDLINE | ID: mdl-38177534
13.
Structural and docking studies of potent ethionamide boosters.
Acta Crystallogr C
; 69(Pt 11): 1243-50, 2013 Nov.
Artículo
Inglés
| MEDLINE | ID: mdl-24192167
14.
Recent advances in Fragment-based strategies against tuberculosis.
Eur J Med Chem
; 258: 115569, 2023 Oct 05.
Artículo
Inglés
| MEDLINE | ID: mdl-37423127
15.
Antibiotics with novel mode of action as new weapons to fight antimicrobial resistance.
Eur J Med Chem
; 256: 115413, 2023 Aug 05.
Artículo
Inglés
| MEDLINE | ID: mdl-37150058
16.
A Three-Step Process to Isolate Large Quantities of Bioactive Sesquiterpene Lactones from Cichorium intybus L. Roots and Semisynthesis of Chicory STLs Standards.
Pharmaceuticals (Basel)
; 16(5)2023 May 22.
Artículo
Inglés
| MEDLINE | ID: mdl-37242554
17.
Rapid and Efficient Access to Novel Bio-Inspired 3-Dimensional Tricyclic SpiroLactams as Privileged Structures via Meyers' Lactamization.
Pharmaceuticals (Basel)
; 16(3)2023 Mar 08.
Artículo
Inglés
| MEDLINE | ID: mdl-36986512
18.
Optimization of pyridylpiperazine-based inhibitors of the Escherichia coli AcrAB-TolC efflux pump.
Eur J Med Chem
; 259: 115630, 2023 Nov 05.
Artículo
Inglés
| MEDLINE | ID: mdl-37459793
19.
Exploring the Antitubercular Activity of Anthranilic Acid Derivatives: From MabA (FabG1) Inhibition to Intrabacterial Acidification.
Pharmaceuticals (Basel)
; 16(3)2023 Feb 22.
Artículo
Inglés
| MEDLINE | ID: mdl-36986435
20.
Design and synthesis of water-soluble prodrugs of rifabutin for intraveneous administration.
Eur J Med Chem
; 238: 114515, 2022 Aug 05.
Artículo
Inglés
| MEDLINE | ID: mdl-35691174