RESUMEN
In radiosurgery (SRS), the geometric uncertainties of machine-related delivery including image-guidance and hence the planning target volume (PTV) are often evaluated by the end-to-end gamma (γ) comparison that carries no information about the clinical relevance of deviations of individual SRS plans during delivery quality assurance (DQA). A proof-of-concept method was proposed to derive the PTV against both the plan- and the machine-specific delivery errors directly from the clinically relevant dose-volume histograms (DVHs) using measured-guided dose reconstruction (MGDR) during DQA. A liquid-filled detector array and a rotating phantom were used to measure sixteen arc-based radiosurgery treatments with 1 and 2 mm gross tumor volume (GTV)-to-PTV margins, producing MGDR-3D dose distribution on both the phantom and the patient CT for γ index and clinical DVH evaluations, respectively. The PTV was considered optimal when the MGDR showed the desired prescription dose coverage (V pres ) of the GTV (100% in this study). Associations of the binary V pres outcomes (Asunto(s)
Malformaciones Arteriovenosas/cirugía
, Meningioma/cirugía
, Neuroma Acústico/cirugía
, Fantasmas de Imagen
, Radiocirugia/métodos
, Planificación de la Radioterapia Asistida por Computador/métodos
, Cirugía Asistida por Computador/métodos
, Malformaciones Arteriovenosas/patología
, Humanos
, Neoplasias Meníngeas/patología
, Neoplasias Meníngeas/cirugía
, Meningioma/patología
, Neuroma Acústico/patología
, Dosificación Radioterapéutica
, Radioterapia de Intensidad Modulada/métodos