Evaluation of thermal conductivity and flexural strength properties of poly(methyl methacrylate) denture base material reinforced with different fillers.

STATEMENT OF PROBLEM: Poly(methyl methacrylate) (PMMA) is widely used in prosthodontics as a denture base material. However, it has several disadvantages, including low strength and low thermal conductivity. PURPOSE: The purpose of this in vitro study was to evaluate thermal conductivity and flexural strength after adding powdered Ag, TiO2, ZrO2, Al2O3, SiC, SiC-nano, Si3N4, and HA-nano in ratios of 10 wt% to PMMA. MATERIAL AND METHODS: A total of 144 specimens were fabricated and divided into 18 groups. Specimens were left in water for 30 days. Thermal conductivity values were measured using a heat flowmeter, flexural strength was measured with a 3-point bend test, and specimens were investigated with environmental scanning electron microscopy. One-way ANOVA was used to compare means followed by using Duncan multiple range test (α=.05). RESULTS: The thermal conductivity value of PMMA increased significantly after the addition of Si3N4, SiC, Al2O3, SiC-nano, TiO2, ZrO2, HA-nano, and Ag. Progressive increases in thermal conductivity were observed in Si3N4, SiC, and Al2O3 fillers. Flexural strength values of the control group were not significantly different from those of the SiC, Al2O3, or Ag group (P>.05). In the other groups, flexural strength values decreased significantly (P<.05). On the basis of electron microscopy, we observed that Si3N4, SiC, and Al2O3 powders had higher thermal conductivity values that are dissipated more homogeneously in PMMA. CONCLUSIONS: Although the addition of 10 wt% SiC, Al2O3, and Ag powder to PMMA significantly increased thermal conductivity, the flexural strength values of PMMA were not significantly changed.

Investigation of toxicity effect of TiCN coated on 304 SS and 410 SS substrates in rat fibroblasts and B-lymphocytes.

In the present study, TiCN thin films were coated on AISI 304 and AISI 410 stainless steel (SS) substrates by Cathodic Arc Physical Vapor Deposition method. TiCN-coated substrates were confirmed by the XRD analysis results. Dense morphology and fine-grained surface of TiCN film were established by SEM images. Cellular toxicity of the coated 304 SS and 410 SS substrates was investigated in the fibroblasts and B-lymphocyte. In respect to that, we have shown coated substrates cytotoxicity, oxidative stress as well as cell viability, reactive oxygen species (ROS), lipid peroxidation (MDA), protein carbonyl, glutathione oxidase (GSSG), and glutathione reductase (GSH) assessment, releasing cytochrome c (Cytc), lysosomal membrane destabilization (AO) may lead to cell death signaling. Our results showed that the coated 304 SS and 410 SS substrates induced cells dysfunction via a significant increase in ROS production, MDA (P < 0.01 and P < 0.001), protein carbonyl (P < 0.05), and GSSG (P < 0.05 and P < 0.01) that correlated to cytochrome c release (P < 0.01). In addition, increased disturbance in oxidative phosphorylation was also shown by the decrease in cell viability (P < 0.001) and GSH (P < 0.01 and P < 0.001) in the coated 304 SS and 410 SS substrates-treated fibroblast and B-lymphocytes. The coated 304 SS and 410 SS substrates contacted cells and trafficked to the lysosomes and this is followed by lysosomal damage, leading to apoptosis/Necrosis. Our results indicated that these materials cause cellular dysfunction and subsequent oxidative stress leading to cognitive impairment in the rat fibroblasts and B-lymphocytes cells.

Effect of coating on the color and surface hardness of the surface of dental ceramics.

BACKGROUND: The aim of this study was to investigate whether boron nitride (BN) and BN-chromium (BN-Cr) coatings applied with the sputtering method would change the characteristics of hardness and discoloration of the ceramic veneer surface. MATERIALS AND METHODS: In this experimental study, thirty disc-shaped cores (10 mm in diameter and 0.8 mm in thickness) were prepared. Three different ceramic systems, IPS Empress (E) (Ivoclar Vivadent, Schaan, Liechntenstein), IPS e.max Press (EP) (Ivoclar Vivadent, Schaan, Liechntenstein), and Turkom Cera (T) (Turcom-Ceramic SDN-BHD, Kuala Lumpur, Malaysia), were tested, each with n = 10. The specimens were divided into two subgroups (n = 5) according to the coating on the veneering ceramic: BN or BN-Cr. The Vickers hardness and color differences (ΔE) values were measured before and after coating. Surface analysis was performed with X-ray diffraction, X-ray photoelectron spectroscopy, and scanning electron microscopic. The Wilcoxon signed-rank test was performed to compare hardness values. The Kruskal-Wallis test was performed to compare ΔE values among all groups. The post hoc tests was used after Kruskal-Wallis, with level of statistical significance set at P ≤ 0.05. RESULTS: BN-Cr coating statistically significantly increased the hardness of all types of ceramics (P < 0.05). BN coating did not change the hardness statistically significantly (P > 0.05). The mean ΔE values indicated clinically noticeable (over the limit of 3.7) color change in all groups except for the EP-BN and T-BN groups. CONCLUSION: Although BN-Cr coating in this thickness had a negative effect on color, it increased the hardness of the ceramics and could be useful in the palatal region.