RESUMEN
A 22-year-old woman with known SLE and chronic hepatitis B developed anginal pain. During this period there was serologic but no other clinical evidence of active SLE. Myocardial perfusion SPECT showed a severe reversible perfusion defect in the posterior wall, and coronary angiography revealed multiple coronary aneurysms in the left anterior descending artery and circumflex artery and total occlusion of the proximal right coronary artery. This case suggests that coronary aneurysms and total occlusion may represent a sequela of arteritis, or of a combination of underlying vasculitis and a recent thrombotic obstruction due to antiphospholipid syndrome.
Asunto(s)
Aneurisma Coronario/complicaciones , Vasos Coronarios/patología , Lupus Eritematoso Sistémico/complicaciones , Adulto , Angina de Pecho/etiología , Angina de Pecho/patología , Síndrome Antifosfolípido/complicaciones , Síndrome Antifosfolípido/patología , Aneurisma Coronario/diagnóstico por imagen , Aneurisma Coronario/patología , Angiografía Coronaria , Enfermedad Coronaria/complicaciones , Enfermedad Coronaria/diagnóstico por imagen , Enfermedad Coronaria/patología , Femenino , Hepatitis B/complicaciones , Hepatitis B/patología , Humanos , Lupus Eritematoso Sistémico/diagnóstico por imagen , Lupus Eritematoso Sistémico/patología , Tomografía Computarizada de Emisión de Fotón Único , Resultado del Tratamiento , Vasculitis/etiología , Vasculitis/patologíaRESUMEN
The National Library of Medicine, in partnership with the National Institute for Dental and Craniofacial Research, the National Eye Institute, the National Science Foundation, the National Institute for Deafness and Other Communication Disorders, and the National Cancer Institute, has founded a software consortium to support the creation of a public resource in high-dimension data processing tools. The initial emphasis of this effort is to provide public software tools in 3D segmentation and deformable and rigid registration, capable of analyzing the head-and-neck anatomy of the Visible Human Project data. The eventual goal is for the consortium to provide the cornerstone of a self-sustaining software community in 3D, 4D and higher dimensional data analysis. The consortium is committed to open-source code, public software including open interfaces supporting connections to a broad range of visualization and graphic user interface platforms.
Asunto(s)
Anatomía Transversal , Procesamiento de Imagen Asistido por Computador , Programas Informáticos , Interfaz Usuario-Computador , Recolección de Datos , Procesamiento Automatizado de Datos , Cabeza , Humanos , National Library of Medicine (U.S.) , Cuello , Estados UnidosRESUMEN
We describe the use of variational implicit surfaces (level sets of an embedded generating function modeled using radial basis interpolants) in anatomic modeling. This technique allows the practitioner to employ sparsely and unevenly sampled data to represent complex biological surfaces, including data acquired as a series of non-parallel image slices. The method inherently accommodates interpolation across irregular spans. In addition, shapes with arbitrary topology are easily represented without interpolation or aliasing errors arising from discrete sampling. To demonstrate the medical use of variational implicit surfaces, we present the reconstruction of the inner surfaces of blood vessels from a series of endovascular ultrasound images.