[Ways of improvement of military epidemiology as a diagnosis and prophylaxis branch of military medicine].

Ways of improvement of military epidemiology as a diagnosis and prophylaxis branch of military medicine. The prospects of development of epidemiological science, training systems and improvement of practice in preventive medicine based on the integration process are considered. The authors emphasize a final recognition of epidemiology as a single diagnostic and preventive discipline the subjects of which are manifestations of epidemic diseases regardless aetiology. An integration of specialists in prophylaxis requires correction of the system of military-medical education and improvement of preventive medical support subsystem of (naval forces). The prospects of inclusion in the educational and scientific processes of the epidemiology of non-communicable diseases, improve the interaction of different structures of military medical services in the field of infectious disease prevention personnel.

[Disease control in the Red Army during the final stages of the Great Patriotic War].

Forms and methods of disease, control in troops were fully developed during the Great Patriotic War 1941-1945 years. An improvement of anti-epidemic organization in the Red Army was based on military medical doctrine, which demanded united views on methods of disease prevention and in accordance with the 'main tasks of medical support of the army, including prevention of epidemic outbreaks in the army. Disease control system in the Red Army during the war was a series of targeted, science-based and proved by military practice measures .aimed at both the prevention and the immediate elimination of epidemic diseases. when they occur. The questions of disease control forces in the final stage of the Great Patriotic War (January 1944 - May 1945). Depending on the progress of the war and the conditions of the fighting, given the period laid down in the principles of disease control of military operations, discussed aspects of the organization of sanitary-epidemiological (preventive) measures in the armed forces.

[Application of administrative enforcement while carrying-out of federal sanitary and epidemiological surveillance in the Armed Forces of the Russian Federation].

The article deals with the legal framework of an application of administrative enforcement. The authors analyzed the information about a quantity and structure of administrative violation in the sanitary and epidemiological welfare, revealed during 2009-2011 while carrying-out of federal sanitary and epidemiological surveillance by the Center for Sanitary and Epidemiological Supervision of the Ministry of Defense (TsGSEN MF RF) in military units and organizations of the Armed Forces of the Russian Federation, and applied administrative sanctions. The acquired data was compared with the same data acquired by The Federal Service for Supervision of Consumer Rights Protection and Human Well-Being (Rospotrebnadzor). The results of research give a reason to consider TsGSEN MF activity according to index of application of administrative enforcement as ineffective. It shows the significant underestimate of administrative sanctions for the failure to comply with requirements of the health legislation. The authors formulated practical recommendations for activation of legal mechanics application by the specialists of TsGSEN MF RF while carrying-out of federal sanitary and epidemiological surveillance in the Armed Forces of the Russian Federation.

[Results of a study of parvovirus B19 (Parvoviridae, Parvovirinae, Erythroparvovirus, Primate erythroparvovirus 1) prevalence and circulation activity in socially significant categories of the population].

Currently, along with the increasing need of medical organizations for blood preparations, algorithms for laboratory testing of blood donors are not available for all infections with hemo-contact mechanism of transmission. A representative example is infection caused by parvovirus В19. PURPOSE OF THE STUDY: The article presents the results of the original study, the purpose of which was to study the prevalence of antibodies to parvovirus B19 and the activity of the circulation of this virus in socially important categories of the population. MATERIAL AND METHODS: The materials of the study were blood samples from blood donors of Saint Petersburg, as well as parvovirus В19 sequences isolated from DNA-positive plasma samples. RESULTS AND DISCUSSION: According to the results of the laboratory examination, a high proportion of carriers of virus-specific IgG antibodies was found in studied group of donors, which confirms the previous infection of parvovirus B19 in them and illustrates the high prevalence of infection in this socially significant group. Based on the results of the blood preparations testing, the presence of parvovirus DNA В19 in a significant number of samples was determined by polymerase chain reaction method. This indicates an current parvovirus infection in the examined donors and points to a high epidemiological risk of the blood products obtained from them. Sequencing and phylogenetic analysis of a fragment of the VP1 gene demonstrated that the studied isolates belonged to А1 genotype and its subtype 1А2, which correlates with the genotypes of parvovirus В19 circulating in the European Union and Asia. In addition, two previously unknown В19 parvovirus isolates were isolated, the nucleotide sequences of which were deposited into the international GenBank database. CONCLUSION: Based on the results of the study, it is justified to include testing of blood samples for markers of В19 parvovirus infection in existing algorithms of laboratory examination of donors, which will ensure prevention of hemo-contact infection of blood recipients with parvovirus В19.