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Understanding the relationship between liquid manipulation and micro-/nanostructured interfaces has gained much attention due to the wide potential applications in many fields, such as chemical and biomedical assays, environmental protection, industry, and even daily life. Much work has been done to construct various materials with interfacial liquid manipulation abilities, leading to a range of interesting applications. Herein, different fabrication methods from the top-down approach to the bottom-up approach and subsequent surface modifications of micro-/nanostructured interfaces are first introduced. Then, interactions between the surface and liquid, including liquid wetting, liquid transportation, and a number of corresponding models, together with the definition of hydrophilic/hydrophobic, oleophilic/olephobic, the definition and mechanism of superwetting, including superhydrophobicity, superhydrophilicity, and superoleophobicity, are presented. The micro-/nanostructured interface, with major applications in self-cleaning, antifogging, anti-icing, anticorrosion, drag-reduction, oil-water separation, water collection, droplet (micro)array, and surface-directed liquid transport, is summarized, and the mechanisms underlying each application are discussed. Finally, the remaining challenges and future perspectives in this area are included.
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This review (with 155 refs.) summarizes the progress made in the past few years in the field of electrochemical sensors based on graphene-derived materials for the determination of heavy metal ions. Following an introduction of this field and a discussion of the various kinds of modified graphenes including graphene oxide and reduced graphene oxide, the review covers graphene based electrodes modified (or doped) with (a) heteroatoms, (b) metal nanoparticles, (c) metal oxides, (d) small organic molecules, (e) polymers, and (f) ternary nanocomposites. Tables are provided that afford an overview of representative methods and materials for fabricating electrochemical sensors. Furthermore, sensing mechanisms are discussed. A concluding section presents new perspectives, opportunities and current challenges. Graphical Abstract Schematic illustration of electrochemical sensor for heavy metal ion sensing based on heteroatom-doped graphene, metal-modified graphene, metal-oxide-modified graphene, organically modified graphene, polymer-modified graphene, and ternary graphene based nanocomposites.
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In this paper, piperazine-grafted reduced graphene oxide (NH-rGO) was synthesized via a simple and green two-step procedure: (i) opening of the resulting epoxides of graphene oxide (GO) with piperazine (NH) through nucleophilic substitution; (ii) reduction of GO with ascorbic acid. Its structure and morphology were characterized by scanning electron microscopy and x-ray photoelectron spectroscopy. The NH-rGO modified glassy carbon electrode was explored as an electrochemical sensor for the determination of Hg(II) using a differential pulse anodic stripping voltammetry technique. Hg(II) can be efficiently accumulated and deposited on the surface of a modified electrode by strong coordination chemical bonds formed between Hg(II) and NH. And then the anodic stripping current can be significantly enhanced by rGO with the merits of large specific surface area and high conductivity, which served as a signal amplifier, finally realizing the highly sensitive determination of Hg(II). The experimental parameters including the pH value of the acetate buffer, deposition potential and deposition time were optimized. Under optimal conditions, the developed sensor exhibited a wide linear range from 0.4-12 000 nM with a low limit of detection of 0.2 nM, which is well below the guideline value in drinking water set by the WHO. Moreover, the practical application of this method was confirmed by an assay of Hg(II) in tap water samples with acceptable results.
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Wearable sweat bioanalysis is promising for non-invasive diagnostics of diseases. However, collection of representative sweat samples without disturbing daily life and wearable bioanalysis of targets that are clinically significant are still challenging. In this work, we report on a versatile method for the sweat bioanalysis. The method is based on a thermoresponsive hydrogel which can imperceptibly absorb slowly secreted sweat without stimulation such as heat or sport exercise. The wearable bioanalysis is accomplished by programmed electric heating of hydrogel modules to 42°C to release absorbed sweat or preloaded reagents into a microfluidic detection channel. Using our method, not only one-step detection of glucose but also multi-step immunoassay of cortisol is accomplished within 1 h, even at a very low sweat rate. Our test results are also compared with those obtained with conventional blood samples and stimulated sweat samples to evaluate the applicability of our method to non-invasive clinical practice.