Sources of nitrous oxide emissions from agriculturally managed peatlands.

The draining and fertilization of peatlands for agriculture is globally an important source of the greenhouse gas nitrous oxide (N2 O). Hitherto, the contribution of major sources to the N2 O emission-that is, fertilization and nitrogen (N) release from peat decomposition-has not yet been deciphered. This hampers the development of smart mitigation strategies, considering that rewetting to halt peat decomposition and reducing N fertilization are promising N2 O emission-reduction strategies. Here, we used machine learning techniques and global N2 O observational data to generalize the distribution of N2 O emissions from agriculturally managed peatlands, to distinguish the sources of N2 O emissions, and to compare mitigation options. N2 O emissions from agriculturally managed croplands were 401.0 (344.5-470.9) kt N year-1 , with 121.6 (88.6-163.3) kt N year-1 contributed by fertilizer N. On grasslands, 64.0 (54.6-74.7) kt N2 O-N year-1 were emitted, with 4.6 (3.7-5.7) kt N2 O-N year-1 stemming from fertilizer N. The fertilizer-induced N2 O emission factor ranged from 1.5% to 3.2%. Reducing the current fertilizer input by 20% could achieve a 10% N2 O emission reduction for croplands but only 3% for grasslands. Rewetting 1.9 Mha cropland and 0.26 Mha grassland would achieve the same N2 O emission reductions. Our results suggest that N2 O mitigation strategies for managed peatlands should be considered separately across land-use types and climatic zones. For croplands, particularly in the tropics, relevant N2 O mitigation potentials are achievable through both fertilizer N reduction and peatland rewetting. For grasslands, management schemes to halt peat degradation (e.g. rewetting) should be considered preferentially for mitigating N2 O and contributing to meeting climate goals.

Cadmium exposure in infants and children: toxicity, health effects, dietary risk assessment and mitigation strategies.

As a non-essential metal, cadmium (Cd) poses a significant threat to food safety and public health. This risk is particularly pronounced for infants and young children due to their high food consumption relative to body weight and immature physiological systems. This review examines the health risks associated with Cd exposure, particularly during the prenatal period through adolescence. It evaluates the prevalence of Cd-rich foods in children's diets and their intake levels across various countries. The review demonstrates that Cd exposure is associated with neurodevelopmental disorders, immune dysfunction, and cardiovascular diseases. It also highlights geographic differences in exposure, with some Asian countries, such as Thailand and China, exhibiting higher overall levels of Cd intake among children compared to other regions. This review presents several recommendations to mitigate Cd intake during early childhood, including reducing the Cd content in food, inhibiting Cd absorption, and promoting its excretion from the body. To minimize the risk of dietary Cd intake in children, it is recommended that stringent regulations of Cd limits in children's food be implemented, alongside a coordinated multi-stakeholder effort. This review provides important insights into effective public health policy development, laying the foundation for achieving broader public health goals.

CAR-T cell therapy in hematological malignancies: Where are we now and where are we heading for?

Chimeric antigen receptor T (CAR-T) therapy has emerged as a revolutionary new pillar in cancer care, particularly in relapsed/refractory (r/r) B-cell malignancies. Following impressive clinical outcomes in hematological malignancies, the FDA-approved six CAR-T cell products for indications such as lymphoma, leukemia, and myeloma. Despite the numerous advantages of CAR-T cell treatment, several challenges exist that interfere with its therapeutic efficacy. Serious adverse effects connected with the treatment continue to be a major concern. In addition, poor persistence of therapeutics and antigen escape frequently result in tumor relapse. Exorbitant treatment cost further remains a significant barrier to its effective implementation, limiting its accessibility. This review presents progress of CAR-T research, the key obstacles that hamper promising outcomes for patients with hematological malignancies, and a few strategies to overcome them.

Toward Low-Carbon Rice Production in China: Historical Changes, Driving Factors, and Mitigation Potential.

Under the "Double Carbon" target, the development of low-carbon agriculture requires a holistic comprehension of spatially and temporally explicit greenhouse gas (GHG) emissions associated with agricultural products. However, the lack of systematic evaluation at a fine scale presents considerable challenges in guiding localized strategies for mitigating GHG emissions from crop production. Here, we analyzed the county-level carbon footprint (CF) of China's rice production from 2007 to 2018 by coupling life cycle assessment and the DNDC model. Results revealed a significant annual increase of 74.3 kg CO2-eq ha-1 in the average farm-based CF (FCF), while it remained stable for the product-based CF (PCF). The CF exhibited considerable variations among counties, ranging from 2324 to 20,768 kg CO2-eq ha-1 for FCF and from 0.36 to 3.81 kg CO2-eq kg-1 for PCF in 2018. The spatiotemporal heterogeneities of FCF were predominantly influenced by field CH4 emissions, followed by diesel consumption and soil organic carbon sequestration. Scenario analysis elucidates that the national total GHG emissions from rice production could be significantly reduced through optimized irrigation (48.5%) and straw-based biogas production (18.0%). Moreover, integrating additional strategies (e.g., advanced crop management, optimized fertilization, and biodiesel application) could amplify the overall emission reduction to 76.7% while concurrently boosting the rice yield by 11.8%. Our county-level research provides valuable insights for the formulation of targeted GHG mitigation policies in rice production, thereby advancing the pursuit of carbon-neutral agricultural practices.

Modelling the impact of human behavior using a two-layer Watts-Strogatz network for transmission and control of Mpox.

PURPOSE: This study aims to evaluate the effectiveness of mitigation strategies and analyze the impact of human behavior on the transmission of Mpox. The results can provide guidance to public health authorities on comprehensive prevention and control for the new Mpox virus strain in the Democratic Republic of Congo as of December 2023. METHODS: We develop a two-layer Watts-Strogatz network model. The basic reproduction number is calculated using the next-generation matrix approach. Markov chain Monte Carlo (MCMC) optimization algorithm is used to fit Mpox cases in Canada into the network model. Numerical simulations are used to assess the impact of mitigation strategies and human behavior on the final epidemic size. RESULTS: Our results show that the contact transmission rate of low-risk groups and susceptible humans increases when the contact transmission rate of high-risk groups and susceptible humans is controlled as the Mpox epidemic spreads. The contact transmission rate of high-risk groups after May 18, 2022, is approximately 20% lower than that before May 18, 2022. Our findings indicate a positive correlation between the basic reproduction number and the level of heterogeneity in human contacts, with the basic reproduction number estimated at 2.3475 (95% CI: 0.0749-6.9084). Reducing the average number of sexual contacts to two per week effectively reduces the reproduction number to below one. CONCLUSION: We need to pay attention to the re-emergence of the epidemics caused by low-risk groups when an outbreak dominated by high-risk groups is under control. Numerical simulations show that reducing the average number of sexual contacts to two per week is effective in slowing down the rapid spread of the epidemic. Our findings offer guidance for the public health authorities of the Democratic Republic of Congo in developing effective mitigation strategies.

Wasted Food, Wasted Resources? A Critical Review of Environmental Impact Analysis of Food Loss and Waste Generation and Treatment.

Food loss and waste (FLW) comes with significant environmental impacts and thus prevents a sustainable food system transition. Here we conducted a systematic review of 174 screened studies that assessed the environmental impacts of FLW generation and treatment. We found that the embodied impacts of FLW along the supply chain and impacts from FLW treatment received equal attention, but few studies have included both. The reviewed studies show narrow geographical (mostly conducted in industrialized countries) and food supply chain (mostly focused on the consumption stage) coverage. Life cycle analysis (LCA), material flow analysis (MFA), or their combination are the most commonly used to quantify FLW related environmental impacts. More method standardization, integration, and innovation and better FLW data with regional and stage resolution from a first-hand source are badly needed. Among the various proposed mitigation strategies covering technology, economy, behavior, and policy aspects, process optimization and waste management options are the most discussed. Our review calls for a more holistic environmental impact assessment of FLW generation and treatment and analysis of the trade-offs among different environmental impact categories and between supply chain stages, which would better inform relevant policy on effective environmental impact mitigation strategies toward sustainable food systems.

Ecotoxicological impact of dinotefuran insecticide and its metabolites on non-targets in agroecosystem: Harnessing nanotechnology- and bio-based management strategies to reduce its impact on non-target ecosystems.

The class of insecticides known as neonicotinoid insecticides has gained extensive application worldwide. Two characteristics of neonicotinoid pesticides are excellent insecticidal activity and a wide insecticidal spectrum for problematic insects. Neonicotinoid pesticides can also successfully manage pest insects that have developed resistance to other insecticide classes. Due to its powerful insecticidal properties and rapid plant absorption and translocation, dinotefuran, the most recent generation of neonicotinoid insecticides, has been widely used against biting and sucking insects. Dinotefuran has a wide range of potential applications and is often used globally. However, there is growing evidence that they negatively impact the biodiversity of organisms in agricultural settings as well as non-target organisms. The objective of this review is to present an updated summary of current understanding regarding the non-target effects of dinotefuran; we also enumerated nano- and bio-based mitigation and management strategies to reduce the impact of dinotefuran on non-target organisms and to pinpoint knowledge gaps. Finally, future study directions are suggested based on the limitations of the existing studies, with the goal of providing a scientific basis for risk assessment and the prudent use of these insecticides.

Tissue distribution, biomagnification, human health risk, and risk mitigation of perfluoroalkyl acids (PFAAs) in the aquatic food web of an urban fringe lake: Insights from urban-rural and seasonal scales.

Perfluoroalkyl acids (PFAAs), renowned for their exceptional physical and chemical properties, are ubiquitous in urban and rural environments. Despite their widespread usage, more knowledge is needed concerning their accumulation and transfer mechanisms within the aquatic food webs of urban fringe lakes, especially across rural-urban and seasonal scales. This study investigated the tissue distribution, bioaccumulation, biomagnification, associated human health risks, and potential risk mitigation strategies of 15 PFAAs within the food web of Luoma Lake, a prototypical urban fringe lake. All targeted PFAAs were detected in samples, with ∑PFAA concentrations ranging from 116.97 to 564.26 ng/g dw in muscles and 26.96-1850.95 ng/g dw in viscera. Spatial variations revealed significantly higher ∑PFAA concentrations in the muscles from the urban subregion (∑PFAA: 359.66 ± 76.48 ng/g dw) compared to the rural subregion (∑PFAA: 328.86 ± 87.51 ng/g dw). Seasonal fluctuations impacted PFAA concentrations in fish and crustacean muscles but exhibited negligible effects on bivalve muscles. Spatial variations only influenced PFAA concentrations in specific viscera (gill, liver, kidney), while seasonal changes had minimal effects on viscera. The organisms demonstrated varying bioaccumulation capacities, with crustaceans displaying the highest bioaccumulation potential, followed by crustaceans and fish. Both spatial and seasonal variations modulated the bioaccumulation patterns of PFAA in muscles, whereas bioaccumulation in viscera was only influenced by seasonal factors. Notably, PFAA biomagnification along the food web was exclusively governed by spatial distribution, remaining unaffected by seasonal changes. The human health risk assessment underscored the potential adverse health impacts of PFOS and PFOA, particularly on young children (aged 2 to <6 years). This study further proposed comprehensive recommendations for mitigating PFAA-induced health risks, encompassing source control, selective consumption, pre-cooking treatments, and strategic cooking method selection. This research provides crucial insights into the ecological behaviors and health implications of PFAA in urban fringe lakes.

Attitudes and Behaviours Regarding COVID-19 Mitigation Strategies in Australians With an Underlying Health Condition: A Cross-Sectional Study.

BACKGROUND: Public health strategies have focused on preventing and slowing the transmission of COVID-19 by promoting the uptake of mitigation strategies. However, little is known about the uptake of these strategies in the presence of underlying health conditions. OBJECTIVES: To describe the attitudes and behaviours of a sample of Australians towards COVID-19 mitigation strategies, and determine if uptake of these strategies differed across different health conditions. DESIGN: Cross-sectional study. SETTING AND PARTICIPANTS: National survey of Australian residents over 18 years. MAIN OUTCOME MEASURES: A purpose-built survey was used to collect participants' attitudes and behaviours towards COVID-19 mitigation strategies. RESULTS: Over half (53%) of the 2867 participants (99% completion rate) reported having one or more comorbidities. The most commonly self-reported health condition was cardiometabolic conditions (28%). Most participants disagreed that masks were no longer needed (74%) and wanted the 5-day isolation mandate (66%). More than one-third would like masks to be mandated for indoor spaces (38%) and 25% avoided going to hospitals. Participants with allergies (OR 1.37; 95% CI 1.14, 1.65), cardiometabolic (OR 1.49; 95% CI 1.23, 1.79), respiratory (OR 1.32; 95% CI 1.07, 1.62) and neurological (OR 1.62; 95% CI 1.12, 2.32) conditions were more likely to avoid using public transport compared to those without. In contrast, participants with underlying mental health conditions were less likely to use N95/P2 facemasks in public spaces (OR 0.46; 95% CI 0.25, 0.87) compared to those without. CONCLUSIONS: A substantial proportion of Australians continued to adopt COVID-19 mitigation measures or expressed a desire for more mitigations, including mandatory isolation for COVID-19, despite the lack of mandates. People with an underlying health condition who represent more than half of all adults appear to be more careful with mitigations to avoid COVID-19. PATIENT OR PUBLIC CONTRIBUTION: Members of the public were invited to participate in a soft launch of the survey between 4th and 5th January 2023 to test flow and functionality, and to allow the final wording of survey questions to be refined as required.

The mask paradox between perception of discomfort and reality of physiological effects in healthy college students in China: a panel study.

BACKGROUND: During the COVID-19 pandemic, masks proved to be an effective measure in preventing virus transmission. However, many people have reported discomfort and negative perceptions toward wearing masks, especially during physical activity. This study aims to evaluate the discomfort and adverse perceptions related to various mask types among young, healthy adults during light exercise, including sitting, stationary stepping, and stair climbing. The study also examines the extent to which masks influence physiological indicators of physical well-being. METHODS: The study was conducted in two stages at the campus hospital of Shantou University. In Stage 1, 20 healthy college students (10 males, 10 females) were recruited to identify the mask with the most substantial physiological and psychological impact among four types: KN95 respirators, surgical masks, cloth masks, and 3D medical masks. These specific types were chosen due to their widespread use and varying levels of filtration and breathability. In Stage 2, 14 healthy college students (7 males, 7 females) were included to examine the effects of the identified mask across various levels of physical exertion. Subjective perceptions were measured using the Mask-Related Discomfort and Perception Score (MRDPS), and physiological parameters such as body temperature, blood pressure, pulse rate, and vital capacity were recorded. RESULTS: The KN95 respirator and cloth mask were associated with the highest MRDPS, indicating significant discomfort among wearers (p < 0.05). The use of KN95 respirators had the largest impact on MRDPS during stair stepping (ß = 10.357, 95% CI [5.755, 14.959]). Physiological parameters showed minor variations across different masks, with KN95 respirators significantly associated with reduced diastolic blood pressure (ß=-7.806, 95% CI [-12.294, -3.318]) and pulse rate (ß=-10.661, 95% CI [-18.896, -2.425]) in Stage 1. However, after controlling for exercise pace in Stage 2, wearing a KN95 respirator did not significantly affect these parameters. CONCLUSIONS: KN95 respirators and cloth masks were found to cause the most discomfort during light physical activity, with males reporting higher discomfort levels than females. While these masks are associated with varying levels of perceived discomfort, their impact on physiological indicators is relatively modest. Future research should include larger and more diverse samples , continuous monitoring of physiological parameters during exercise, and exploration of the underlying mechanisms of gender differences in mask discomfort.

Collateral effects of COVID-19 stay-at-home orders on violence against women in the United States, January 2019 to December 2020.

BACKGROUND: The necessary execution of non-pharmaceutical risk-mitigation (NPRM) strategies to reduce the transmission of COVID-19 has created an unprecedented natural experiment to ascertain whether pandemic-induced social-policy interventions may elevate collateral health risks. Here, we assess the effects on violence against women (VAW) of the duration of NPRM measures that were executed through jurisdictional-level orders in the United States. We expect that stay-at-home orders, by reducing mobility and disrupting non-coresident social ties, are associated with higher incident reporting of VAW. METHODS: We used aggregate data from the Murder Accountability Project from January 2019 through December 2020, to estimate count models examining the effects of the duration of jurisdictional-level (N = 51) stay-at-home orders on femicide. Additionally, we used data from the National Incident-Based Reporting System to estimate a series of count models that examined the effects of the duration of jurisdictional-level (N = 26) stay-at-home orders on non-lethal violence against women, including five separate measures of intimate partner violence (IPV) and a measure of non-partner sexual violence. RESULTS: Results from the count models indicated that femicide was not associated with COVID-19 mitigation strategies when adjusted for seasonal effects. However, we found certain measures of non-lethal VAW to be significantly associated in adjusted models. Specifically, reported physical and economic IPV were positively associated with stay-at-home orders while psychological IPV and non-partner sexual violence were negatively associated with stay-at-home orders. The combination measure of all forms of IPV was positively associated with the duration of stay-at-home orders, indicating a net increase in risk of IPV during lockdowns. CONCLUSIONS: The benefits of risk-mitigation strategies to reduce the health impacts directly associated with a pandemic should be weighed against their costs with respect to women's heightened exposure to certain forms of violence and the potentially cascading impacts of such exposure on health. The effects of COVID-19 NPRM strategies on IPV risk nationally and its immediate and long-term health sequelae should be studied, with stressors like ongoing pandemic-related economic hardship and substance misuse still unfolding. Findings should inform the development of social policies to mitigate the collateral impacts of crisis-response efforts on the risk of VAW and its cascading sequelae.

Overdispersion in COVID-19 increases the effectiveness of limiting nonrepetitive contacts for transmission control.

Increasing evidence indicates that superspreading plays a dominant role in COVID-19 transmission. Recent estimates suggest that the dispersion parameter k for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is on the order of 0.1, which corresponds to about 10% of cases being the source of 80% of infections. To investigate how overdispersion might affect the outcome of various mitigation strategies, we developed an agent-based model with a social network that allows transmission through contact in three sectors: "close" (a small, unchanging group of mutual contacts as might be found in a household), "regular" (a larger, unchanging group as might be found in a workplace or school), and "random" (drawn from the entire model population and not repeated regularly). We assigned individual infectivity from a gamma distribution with dispersion parameter k We found that when k was low (i.e., greater heterogeneity, more superspreading events), reducing random sector contacts had a far greater impact on the epidemic trajectory than did reducing regular contacts; when k was high (i.e., less heterogeneity, no superspreading events), that difference disappeared. These results suggest that overdispersion of COVID-19 transmission gives the virus an Achilles' heel: Reducing contacts between people who do not regularly meet would substantially reduce the pandemic, while reducing repeated contacts in defined social groups would be less effective.

Examining social vulnerability to multi-hazards in North-Western Himalayas, India.

The enhancing risk from human action and multi-hazard interaction has substantially complicated the hazard-society relationship. The underlying vulnerabilities are crucial in predicting the probable impact to be caused by multi-hazards. Thus, the evaluation of social vulnerability is decisive in inferring the driving factor and preparing for mitigation strategies. The Himalayan landscape is prone to multiple hazards as well as possesses a multitude of vulnerabilities owing to changing human landscape. Thus, an attempt has been made to inquire into the underlying socioeconomic factors enhancing the susceptibility of the region to multi-hazards. The social vulnerability index (SVIent) has been introduced, consisting of 13 indicators and 33 variables. The variables have been standardized using the maximum and minimum normalization method and the relative importance for each indicator has been determined using Shannon entropy methods to compute SVIent. The findings revealed that female population, population above 60 years old, net irrigated area, migrant population, dilapidated house, nonworkers, bank, and nonworkers seeking jobs were found to be relatively significant contributors to the vulnerability. The western part of the study area was classified as the highly vulnerable category (SVI > 0.40628), attributed to high dependence, and higher share of unemployed workers and high poverty. The SVIent was shown to have positive correlation between unemployment, socioeconomic status, migration, dependency, and household structure significant at two-tailed test. The study's impact can be found in influencing the decision of policymakers and stakeholders in framing the mitigation strategies and policy documents.

Climatic zoning of yerba mate and climate change projections: a CMIP6 approach.

Yerba mate (Ilex paraguariensis) is renowned for its nutritional and pharmaceutical attributes. A staple in South American (SA) culture, it serves as the foundation for several traditional beverages. Significantly, the pharmaceutical domain has secured numerous patents associated with this plant's distinctive properties. This research delves into the climatic influence on yerba mate by leveraging the CMIP6 model projections to assess potential shifts brought about by climate change. Given its economic and socio-cultural significance, comprehending how climate change might sway yerba mate's production and distribution is pivotal. The CMIP6 model offers insights into future conditions, pinpointing areas that are either conducive or adverse for yerba mate cultivation. Our findings will be instrumental in crafting adaptive and mitigative strategies, thereby directing sustainable production planning for yerba mate. The core objective of this study was to highlight zones optimal for Ilex paraguariensis cultivation across its major producers: Brazil, Argentina, Paraguay, and Uruguay, under CMIP6's climate change forecasts. Our investigation encompassed major producing zones spanning the North, Northeast, Midwest, Southeast, and South of Brazil, along with the aforementioned countries. A conducive environment for this crop's growth features air temperatures between 21 to 25 °C and a minimum precipitation of 1200 mm per cycle. We sourced the current climate data from the WorldClim version 2 platform. Meanwhile, projections for future climatic parameters were derived from WorldClim 2.1, utilizing the IPSL-CM6A-LR model with a refined 30-s spatial resolution. We took into account four distinct socio-economic pathways over varying timelines: 2021-2040, 2041-2060, 2061-2081, and 2081-2100. Geographic information system data aided in the spatial interpolation across Brazil, applying the Kriging technique. The outcomes revealed a majority of the examined areas as non-conducive for yerba mate cultivation, with a scanty 12.25% (1.5 million km2) deemed favorable. Predominantly, these propitious regions lie in southern Brazil and Uruguay, the present-day primary producers of yerba mate. Alarming was the discovery that forthcoming climatic scenarios predominantly forecast detrimental shifts, characterized by escalating average air temperatures and diminishing rainfall. These trends portend a decline in suitable cultivation regions for yerba mate.

How to address the barriers to meaningful adolescent involvement in health research: A qualitative study.

The under-involvement of adolescents in health research has been attributed to multiple barriers faced by both researchers and adolescents. Despite identifying these barriers, the literature offers few solutions, mostly from the perspective of researchers. To address this, we conducted a qualitative study to explore effective strategies to address these barriers from the perspective of both researchers and adolescents. We conducted semi-structured interviews with adolescents (n = 25) and researchers (n = 25) from 14 countries. We included adolescents aged 10-24 years with experience of contributing to health research studies and health researchers with experience of engaging adolescents in health research. The interviews explored the mitigation strategies to commonly reported barriers to meaningful adolescent involvement for researchers and adolescents. Data were analyzed using reflexive thematic analysis. We identified three overarching strategies to address the commonly experienced barriers to adolescent involvement. First, participants suggested the need to plan for adequate resources, organizational support, capacity building, accessibility, compensation, and adolescents' safety. Second, they recommended building relationships by engaging the community, fostering trust and respect with adolescents, promoting teamwork, and maintaining transparent communication. Third, they proposed making involvement engaging for adolescents by creating a conducive environment, increasing their representation, using interesting methods, and addressing power dynamics. These findings build on the current best practices for adolescent involvement in health research by highlighting which strategies should be incorporated early on to plan for and prevent potential challenges to adolescent involvement.

Network Latency in Teleoperation of Connected and Autonomous Vehicles: A Review of Trends, Challenges, and Mitigation Strategies.

With remarkable advancements in the development of connected and autonomous vehicles (CAVs), the integration of teleoperation has become crucial for improving safety and operational efficiency. However, teleoperation faces substantial challenges, with network latency being a critical factor influencing its performance. This survey paper explores the impact of network latency along with state-of-the-art mitigation/compensation approaches. It examines cascading effects on teleoperation communication links (i.e., uplink and downlink) and how delays in data transmission affect the real-time perception and decision-making of operators. By elucidating the challenges and available mitigation strategies, the paper offers valuable insights for researchers, engineers, and practitioners working towards the seamless integration of teleoperation in the evolving landscape of CAVs.

Heat stress and ram semen production and preservation: Exploring impacts and effective strategies.

As global warming persists, heat stress (HS) continues to affect animals, particularly those raised in extensive systems such as sheep. As a result, there is a growing body of research investigating the physiological and biological consequences of HS on these animals. Recent studies have specifically examined the effects of climate change, global warming, and HS on gametes. Heat stress has been shown to affect ram semen production, resulting in decreased sperm quality and volume in both fresh and stored samples. This is attributed to the effect of heat on hormone production in the testicles, which is critical for successful spermatogenesis. Such effects can have significant consequences on the fertility of female sheep, which could affect the farmers' revenue. Therefore, farmers and researchers are utilizing various strategies and laboratory techniques to mitigate these negative effects. This review aims to comprehensively evaluate the impact of HS on ram semen production and conservation and analyze the different mitigation strategies at various levels, including management and nutritional interventions. The findings of this review will serve as a critical foundation for the development of targeted interventions and sustainable practices in sheep farming, ensuring resilient and profitable operations in the face of ongoing global climate challenges.

Influence of acute mild winter conditions on the productivity of feedlot cattle: An Australian perspective.

The impact of cold stress on feedlot cattle has received limited investigation in temperate climates. However, cold stress has been found to impact cattle welfare and production in temperate climatic conditions, where ambient temperature (TA), precipitation, relative humidity (RH), wind speed (WS) and solar radiation (SR) all influencing apparent temperature. While there are many indices to quantify cold stress in cattle, there are limited indices that directly relate to cattle and account for all the interactions between climatic variables. This makes cold stress difficult to quantify, with on-cattle measures such as core body temperature and shivering difficult metrics to obtain in feedlot cattle. Moreover, individual cattle will react differently to cold conditions based on their production, age, sex, coat characteristics (colour and type), breed and nutrition. While cold stress can be difficult to measure, the production status, behavioural and physiological effects of cold stress have been identified, but generally under what could be considered as extreme cold stress events. Similarly, while mitigation strategies such as shelter, bedding and windbreaks have been investigated, limited information is available surrounding their usefulness in temperate climates. Further research is needed to fully investigate the effects of cold stress and how to mitigate those effects in feedlot cattle under conditions, such as those found in Australia.

Synergistic control of urban heat island and urban pollution island effects using green infrastructure.

Urban heat island (UHI) and urban pollution island (UPI) effects are two major challenges that affect the liveability and sustainability of cities under the circumstance of climate change. However, existing studies mostly addressed them separately. Urban green infrastructure offers nature-based solutions to alleviate urban heat, enhance air quality and promote sustainability. This review paper provides a comprehensive synthesis of the roles of urban green spaces, street trees, street hedges, green roofs and vertical greenery in mitigating UHI and UPI effects. These types of green infrastructure can promote the thermal environment and air quality, but also potentially lead to conflicting impacts. Medium-sized urban green spaces are recommended for heat mitigation because they can provide a balance between cooling efficiency and magnitude. Conversely, street trees pose a complex challenge since they can provide cooling through shading and evapotranspiration while hindering pollutant dispersion due to reduced air ventilation. Integrated research that considers simultaneous UHI and UPI mitigation using green infrastructure, their interaction with building features, and the urban geographical environment is crucial to inform urban planning and maximize the benefits of green infrastructure installations.

Ammonia-stressed anaerobic digestion: Sensitivity dynamics of key syntrophic interactions and methanogenic pathways-A review.

The problematic anaerobic digestion (AD) of protein-rich substrates owing to their high ammonia content continues to hinder optimum methanation despite their high potential for offsetting greenhouse gas (GHG) emissions. This review focuses on the analyses of the sensitivity dynamics of key AD processes as well as the microbial interactions and exchanges that occur with them. Aside from the apparent increased risk associated with thermophilic ammonia-rich substrate AD, the marginally higher energy generation compared to mesophilic systems is not commensurate to the energy requirement. Moreover, while comparable FAN thresholds have been confirmed, TAN thresholds are susceptible to physical chemistry and so vary greatly. Profiling of the metabolic capability of front-end AD microbiome revealed Bacteroidetes, Firmicutes, and Synergistetes as some of the ammonia-resilient bacteria groups while Proteobacteria and Actinobacteria were the most fragile taxa. Besides the predominance of incomplete propionate oxidizing bacteria under ammonia stress conditions, syntrophic propionate oxidation (SPO) is usually shifted from the methylmalonyl CoA to the dismutation pathway. Furthermore, besides their different recoverability potentials, distinct methanogenic groups are differentially impacted by different ammonia species. Prevailing literature evidence suggests that conductive material assisted bioaugmentation with SAO-HM consortia, and in-situ H2 supplementation are the most effective for expediting electron transfer and relieving ammonia stress. These valuable insights should inform the design of targeted ammonia inhibition mitigation strategies.