1.
Fitoterapia
; 130: 43-47, 2018 Oct.
Artículo
en Inglés
| MEDLINE
| ID: mdl-30076886
RESUMEN
Five new guaiane-type sesquiterpenoid dimers vielopsides A-E, connecting patterns through two direct CC bonds (C-2 to C-2', C-4 to C-1'), were isolated from the roots of Xylopia vielana. Their absolute configurations were established by NOE analysis, the Cu Kα X-ray crystallographic and circular dichroism (CD) experiment. Among them, compound 5 showed moderate activity IC50 values of 33.8⯵M on NO production in RAW 264.7 macrophages.