Manifesto on united airways diseases (UAD): an Interasma (global asthma association - GAA) document.

OBJECTIVE: The large amount of evidence and the renewed interest in upper and lower airways involvement in infectious and inflammatory diseases has led Interasma (Global Asthma Association) to take a position on United Airways Diseases (UAD). METHODS: Starting from an extensive literature review, Interasma executive committee discussed and approved this Manifesto developed by Interasma scientific network (INES) members. RESULTS: The manifesto describes the evidence gathered to date and defines, states, advocates, and proposes issues on UAD (rhinitis, rhinosinusitis and nasal polyposis), and concomitant/comorbid lower airways disorders (asthma, chronic obstructive pulmonary disease, bronchiectasis, cystic fibrosis, obstructive sleep apnoea) with the aim of challenging assumptions, fostering commitment, and bringing about change. UAD refers to clinical pictures characterized by the coexistence of upper and lower airways involvement, driven by a common pathophysiological mechanism, leading to a greater burden on patient's health status and requiring an integrated diagnostic and therapeutic plan. The high prevalence of UAD must be taken into account. Upper and lower airways diseases influence disease control and patient's quality of life. CONCLUSIONS: Patients with UAD need to have a timely and adequate diagnosis, treatment, and, when recommended, referral for management in a specialized center. Diagnostic testing including skin prick or serum specific IgE, lung function, fractional exhaled nitric oxide (FeNO), polysomnography, allergen-specific immunotherapies, biological therapies and home based continuous positive airway pressure (CPAP) whenever these are recommended, should be part of the management plan for UAD. Education of medical students, physicians, health professionals, patients and caregivers on the UAD is needed.

Manifesto on inhaled triple therapy in asthma: an Interasma (Global Asthma Association - GAA) document.

Objective: The optimal use of drug combinations for the management of asthma is providing significant results. This has prompted Interasma (Global Asthma Association) to take a position on inhaled triple therapy in asthma.Methods: We performed an extensive literature research to clinical trials, meta-analyses, randomized controlled trials and systematic reviews.Results: Starting from an extensive literature review, Interasma executive committee discussed and approved this Manifesto, developed by Interasma scientific network (INES) members.Conclusions: The manifesto describes the evidence gathered to date and states, advocates, and proposes issues on inhaled corticosteroid (ICS) plus long-acting beta 2 agonist (LABA) and long-acting muscarinic antagonists (LAMA) with the aim of challenging assumptions, fostering commitment, and bringing about change.

A Manifesto for exercise science - a vision for improving the health of the public and planet.

In this manifesto, we make the case that Exercise Science can and must do more to improve the health of the public and the planet. Post pandemic, our vision for Exercise Science is one of a maturing scientific discipline reaching outwards from a base of strong empirical evidence to have a profound and sustained positive global impact on health. In each of the three main areas of the discipline - research, teaching, and professional practice - a new and distinctive approach is needed. We propose 12 points of action, in no particular order, for a). quality, rigour, and professional standing, and b). reach, relevance, and public engagement and make numerous suggestions for action and change. We encourage the teachers, researchers and practitioners of Exercise Science to consider and act on these recommendations. We hope that this manifesto can help create a shared sense of purpose amongst the global Exercise Science community and further the principles of equality, diversity and inclusion. To act on these principles, we need to cultivate a discipline that encourages more women, people who experience racism and other forms of discrimination, and people with a disability to become involved in the discipline.

The Leiden Manifesto and Research Assessment.

Evaluation of scientific research is essential to judge the impact of research and the author. In this regard, a newly devised Leiden Manifesto describes 10 principles for guiding research evaluation. The principles need to be analyzed critically and adapted as a preferred method of research evaluation.

EBCC-14 manifesto: Addressing disparities in access to innovation for patients with metastatic breast cancer across Europe.

The European Breast Cancer Council (EBCC) traditionally identifies controversies or major deficiencies in the management of patients with breast cancer and selects a multidisciplinary expert team to collaborate in setting crucial principles and recommendations to improve breast cancer care. The 2024 EBCC manifesto focuses on disparities in the care of patients with metastatic breast cancer. There are several reasons for existing disparities both between and within countries. Our recommendations aim to address the stigma of metastatic disease, which has led to significant disparities in access to innovative care regardless of the gross national income of a country. These recommendations are for different stakeholders to promote the care of patients with metastatic breast cancer across Europe and worldwide.

A Manifesto for transformative action on HIV among Black communities in Canada.

Black communities bear a hugely disproportionate share of Canada's HIV epidemic. Black persons annually represent up to one quarter of new diagnoses, while in contrast, diagnoses have been falling among white Canadians for the past two decades. There has been a notable lack of urgency and serious debate about why the trend persists and what to do about it. For too long, public institutions have reproduced hegemonic white supremacy and profoundly mischaracterized Black life. Consequently, Black communities suffer policies and programs that buttress systemic anti-Black racism, socio-economically disenfranchise Black communities, and in the process marginalize knowledgeable, experienced, and creative Black stakeholders. The Interim Committee on HIV among Black Canadian Communities (ICHBCC) is a group of Black researchers, service providers, and community advocates who came together in early 2022 to interject urgency to the HIV crisis facing Black communities. Specifically, the ICHBCC advocates for self-determined community leadership of research, policies, and programs, backed by access to appropriate resources, to change the trajectory of HIV among Black Canadian communities. In this article, we introduce the wider community to the Black HIV Manifesto that we developed in 2022.

RéSUMé: Les communautés noires constituent une part très disproportionnée de l'épidémie de VIH du Canada. Les personnes noires représentent annuellement jusqu'au quart des nouveaux diagnostics, tandis que les diagnostics diminuent chez les Canadiennes et les Canadiens de race blanche depuis 20 ans. Il y a une absence notable d'urgence et de débat sérieux sur la raison de la persistance de ces tendances et sur ce qu'il faudrait y faire. Pendant trop longtemps, les institutions publiques ont reproduit l'hégémonie de la suprématie blanche et extrêmement mal caractérisé les vies noires. Par conséquent, les communautés noires souffrent de politiques et de programmes qui soutiennent le racisme anti-Noirs systémique, privent les communautés noires de leurs droits socioéconomiques et marginalisent ainsi les connaissances, l'expérience et la créativité des parties prenantes noires. Le comité intérimaire sur le VIH dans les communautés noires du Canada (ICHBCC) est un groupe de chercheurs et de chercheuses, de prestataires de services et de porte-parole communautaires de race noire qui se sont regroupés au début de 2022 pour mettre l'accent sur le caractère urgent de la crise du VIH dans les communautés noires. Plus précisément, l'ICHBCC plaide en faveur d'un leadership communautaire autodéterminé de la recherche, des politiques et des programmes, appuyé par un accès aux ressources nécessaires, pour changer la trajectoire du VIH dans les communautés noires du Canada. Dans cet article, nous présentons à l'ensemble de la communauté le « manifeste noir sur le VIH ¼ que nous avons élaboré en 2022.

Clinical manifestation and maternal complications and neonatal outcomes in pregnant women with COVID-19: a comprehensive evidence synthesis and meta-analysis.

OBJECTIVES: There is little known about pregnancy-related complications and comorbidity in this group of women. Therefore, this systematic review and meta-analysis were performed to find out whether COVID-19 may cause different manifestations and outcomes in the antepartum and postpartum period or not. MATERIAL AND METHODS: We searched databases, including Medline (PubMed), Embase, Scopus, Web of sciences, Cochrane library, Ovid, and CINHAL to retrieve all articles reporting the prevalence of maternal and neonatal complications, in addition to clinical manifestations, in pregnant women with COVID-19 that published with English language January to November 2020. RESULTS: Seventy-four studies with total 5560 pregnant women included in this systematic review. The results show that the pooled prevalence of neonatal mortality, lower birth weight, stillbirth, premature birth, and intrauterine fetal distress in women with COVID-19 was 4% (95% Cl: 1 - 9%), 21% (95% Cl: 11 - 31%), 2% (95% Cl: 1 - 6%), 28% (95% Cl: 13 - 43%), and 14% (95% Cl: 4 - 25%); respectively. Moreover, the pooled prevalence of fever, cough, diarrhea, and dyspnea were 56% (95% Cl: 32 - 81%), 29% (95% Cl: 21 - 38%), 9% (95% Cl: 2 - 16%), and 3% (95% Cl: 1 - 6%) in pregnant women with COVID-19. Two studies reported that pregnant women with severe COVID pneumonia have higher levels of d-dimer. Also, COVID pneumonia is more common in pregnant women than non-pregnant. CONCLUSION: According to this meta-analysis, pregnant women with COVID-19 with or without pneumonia, are at a higher risk of preeclampsia, preterm birth, miscarriage and cesarean delivery. Furthermore, the risk of LBW and intrauterine fetal distress seems to be increased in neonates. In addition, our evaluations are investigative of higher risk of COVID-19 in the third trimester in pregnant women comparing to the first and second trimester. It can be due to higher BMI in the third trimester causing to increase the likelihood of disease deterioration, which can trigger a cascade of side effects starting with coagulation, pneumonia, hypoxemia affecting the placenta leading to ICU admission, fetal distress, premature birth and higher rates of C-section.

The road to a human-centred digital society: opportunities, challenges and responsibilities for humans in the age of machines.

The growing adoption of intelligent technologies has brought us to a crossroad. The creators of intelligent technologies are acquiring the power to influence a wide variety of outcomes that are important to human end-users. In doing so, those same intelligent technologies are being used to undermine and even actively harm the interests of those same end-users. In the absence of a recalibration, we are almost certainly headed down a path wherein intelligent technologies will primarily serve the interests of developers and owners of technology rather than humankind at large. In an attempt to push for such a recalibration, we present parallels between the 2008 financial crisis and the current state of affairs. Following which, we present a list of recommendations and implications to be used when in the pursuit of creating responsible and human-centred AI.

The Emancipatory Design Manifesto: Let's Suppose That Disability Does Not Exist.

In this paper we present and propose the concept of Emancipatory Design (ED), which is an alternative way of thinking about the human being and the ever intricate relations between people, design, architecture and the built environment. The paper is given the form of a manifesto and has the overall aim to reflect critically on the possibility of design as a practice that potentially carry emancipatory effects in the everyday lives of particular human beings. Defining ED, we draw on notions from philosophy and the history of ideas to challenge the concept of human disability often at play in writings concerned with design and architecture. This approach allows for a provocative, disruptive and experimental attempt to relativize and cancel the notion of disability - and, subsequently, to explore the possibilities inherent to this maneuver in the realm of design thinking. With ED we propose a concept that works as a contribution to the community engaged in Universal Design (UD), as well as a gentle objection and critique of the abstract and intangible element of universality at play within this tradition.

Why is appropriate healthcare inaccessible for many European breast cancer patients? - The EBCC 12 manifesto.

In Europe, inappropriate reimbursement and funding rules and regulations act as disincentives to best breast cancer care or, at worst, hinder best care. This problem was the focus of the 12th European Breast Cancer Conference (EBCC) manifesto, discussed during the virtual conference. As patient involvement is indispensable in driving changes to clinical practice, Europa Donna the European patient advocacy group was closely involved in the 12th manifesto. Reimbursement policies have rarely evolved with advances in breast cancer care such as outpatient (ambulatory) care rather than inpatient admission, use of oral or subcutaneous anti-cancer drugs rather than day-hospital intravenous administration, oncoplastic surgery techniques to minimize mastectomy rates, breast reconstructive surgery, risk-reducing surgery for BRCA mutation carriers, or use of hypo-fractionated breast radiation therapy. Although each European country, region and centre will have to understand how their reimbursement policies may hinder best care and find their own solutions, the problems are similar throughout Europe and some solutions can be broadly applied. This manifesto is not calling for more funding or demanding changes that will result in more expensive care. Reimbursement, if better aligned with guidelines and optimal clinical practice, will deliver more cost-effective healthcare. This will release resources, support more equitable use of finite funding and resources, so allowing more European breast cancer patients to benefit from evidence-based treatment recommended by national and international guidelines.

Aligning the "Manifesto for a European Research Network into Problematic Usage of the Internet" with the Diverse Needs of the Professional and Consumer Communities Affected by Problematic Usage of Pornography.

The Manifesto for a European research network into Problematic Usage of the Internet was published in May 2018. It was written from the perspective of the COST Action Network, a programme of the European Cooperation in Science and Technology CA16207 and is expected to have significant influence on research funding priorities over the next decade. The Manifesto identified nine key research priorities to advance understanding in the field. Our analysis shows that while at the most general level it identified problematic usage of pornography (PUP) as a key research priority, it then barely mentioned it again within the body of the report. This paper uses the Manifesto's framework to suggest research areas into the problematic usage of pornography which are of particular relevance to clinicians and other professionals working in the field who want to develop approaches to assist individuals and target groups affected by PUP. It also looks at potential research opportunities inspired by the lived-experience of users withdrawing from PUP. A large number of opportunities are identified for new work on PUP across all nine key research areas of the Manifesto.

Pattern of health promises for Indian democracy: A qualitative review of political manifestos.

INTRODUCTION: India is a multiparty parliamentary democracy and second most populous country in the world. In spite of pressing needs of the population, healthcare is still not considered a driving electoral mobilizer as compared to the older democracies such as the UK and USA. Only three National Health Policies (1983, 2002 and 2017) have been promulgated by the respective governments during the past 70 years of India's independence. National policies are often preceded by commitment of political parties documented in the manifestos. Type and nature of promises in the manifesto of National Political Parties (NPPs) are reflective of vision and intentions of parties. The present study was done to qualitatively analyze the pattern of expressed intensions in terms of health promises made for 16th Lok Sabha (people house) elections of India in the year 2014 by its NPPs. METHODS: Manifestos of NPP, as notified by election commission of India, were retrieved from their respective website and effort was also made with an online search. Manifesto of five out of total seven NPPs could be accessed and analyzed. Consensus-based criteria of assessment were developed by public health experts and each manifesto was assessed independently by two experts. In a case of difference in scoring, independent opinion was sought from the third expert for adjudication. RESULTS: Two NPPs mentioned majority of statements as goals and rest focused for health strategies. The focus of statements was for public health problems (11.5%), public health financing (9.0%), and improving infrastructure (9.0%). All parties were committed for improving health services as it shared 30.8% space as statements in all five manifestos. All statements were of primary or secondary prevention in nature and focused more on improving processes (47.4%) and increasing inputs (31.6%). Whereas, Communist Party of India focused only on inputs (60.0%) and outputs (40.0%). CONCLUSION: Promises made by all NPPs were quite progressive, inclusive, and comprehensive in nature; however, much of these do not find space in public debates on television and election speeches.

European Breast Cancer Conference manifesto on breast centres/units.

MANIFESTO-CALL TO ACTION.

Optimal breast cancer pathology manifesto.

This manifesto was prepared by a European Breast Cancer (EBC) Council working group and launched at the European Breast Cancer Conference in Glasgow on 20 March 2014. It sets out optimal technical and organisational requirements for a breast cancer pathology service, in the light of concerns about variability and lack of patient-centred focus. It is not a guideline about how pathology services should be performed. It is a call for all in the cancer community--pathologists, oncologists, patient advocates, health administrators and policymakers--to check that services are available that serve the needs of patients in a high quality, timely way.

Manifiesto por la Psicología en Chile: A propósito de la revuelta del 18 de Octubre 2019 / Manifesto for Psychology in Chile: On the subject of the revolt of October 18, 2019

Resumen La psicología en tanto práctica profesional y de investigación científica no puede ni debe permanecer aislada de los contextos en los que se desarrolla. Frente a los profundos sentimientos de malestar expresados por el pueblo chileno en movilizaciones sociales desde el 18 de octubre de 2019, que responden directamente a la implementación de un modelo neoliberal desprovisto de justicia social, como psicólogas y psicólogos nos sentimos llamados a levantar los requerimientos mínimos que consideramos que nuestra disciplina debe asumir. Bajo este marco, se presenta un Manifiesto que contempla 22 puntos, construido de manera colaborativa por 13 psicólogas y psicólogos de diversas instituciones que, en una labor colectiva, lo proponen como agenda de trabajo para los próximos meses. Sabiendo que este listado no es definitivo ni exhaustivo, lo ofrecemos a la comunidad como un punto de partida para la deliberación, discusión y debate dentro de Universidades, centros de investigación, sociedades científicas y profesionales y al aparato estatal, de manera de fortalecer el rol de la psicología en la problematización y reducción las inequidades e injusticias, así como en el fomento del bienestar psicosocial.

Abstract Psychology as a professional and scientific practice should and must not remain isolated from the contexts in which it develops. Considering the deep feelings of discomfort expressed by the Chilean people during social mobilizations since October 18th, 2019, in response to the implementation for decades of a neoliberal model devoid of social justice, as psychologists we feel summoned to raise the minimum requirements we think our discipline must assume about that matter. Under these assumptions, a Manifesto is presented. It includes 22 items, which have been elaborated by 13 psychologists from several institutions that, in a collective effort, propose them as an agenda to work on in the next months. Knowing that this list is not definitive or exhaustive, we offer it to the community as a point of departure for deliberation, discussion and debate within universities, research centers, scientific and professional societies, and the state apparatus, in order to strengthen the role of psychology in the problematization and reduction of inequities and injustices, as well as in promoting psychosocial well-being.

Predictores de prejuicio sutil y manifiesto en el norte de Chile

El propósito del presente estudio es examinar la relación entre diversas variables como predictores del prejuicio racista (sutil y manifiesto) y proponer un modelo de ecuaciones estructurales que exprese adecuadamente su relación. Estas variables incluyen: el autoritarismo, la orientación a la dominancia social, el conservadurismo y el hetero-estereotipo. Se busca establecer si todas ellas presentan una relación directa, indirecta o nula con el prejuicio. Como resultado se constató el prejuicio racista, se proponen y presentan evaluación del ajuste, de dos modelos predictivos del prejuicio, a los datos obtenidos. El estudio propone un modelo unifactorial y otro bifactorial, ambos con buenos indicadores de bondad de ajuste. Esta investigación cobra relevancia, considerando la situación de ciudad fronteriza de Arica y el aumento de inmigrantes latinoamericanos en los últimos años, hacia Chile.

The purpose of this study is to examine the relationship between various variables as predictors of racist prejudice (subtle and manifest) and propose a model of structural equations that adequately expresses their relationship. These variables include: authoritarianism, orientation to social dominance, conservatism and hetero-stereotype. It seeks to establish whether all of them have a direct, indirect or null relationship with prejudice. As a result, the racist prejudice was verified, and the evaluation of the data obtained from two predictive models of prejudice is proposed and presented. The study proposes a unifactorial and a bifactorial model, both with good indicators of goodness of fit. This research becomes relevant, considering the situation of the border city of Arica and the increase of Latin American immigrants in recent years, towards Chile.

O objetivo deste estudo é examinar a relação entre várias variáveis como preditores de preconceito racista (sutil e manifesto) e propor um modelo de equações estruturais que expressem adequadamente sua relação. Essas variáveis incluem: autoritarismo, orientação ao domínio social, conservadorismo e heteroestereótipo. Ele procura estabelecer se todos eles têm uma relação direta, indireta ou nula com o preconceito. Como resultado, foi encontrado o preconceito racista, e dois modelos de avaliação do preconceito são propostos e apresentam ajuste aos dados obtidos. O estudo propõe um modelo unifatorial e um modelo bifatorial, ambos com bons indicadores de qualidade de ajuste. Esta pesquisa se torna relevante, considerando a situação da cidade fronteiriça de Arica e o aumento de imigrantes latino-americanos nos últimos anos, em direção ao Chile

A felicidade clandestina para Clarice Lispector / La felicidad clandestina para Clarice Lispector / The clandestine happiness for Clarice Lispector

A autora comenta o conto Felicidade clandestina, de Clarice Lispector, utilizando referencial psicanalítico...

The author comments the short story Clandestine happiness (Felicidade clandestina), by Clarice Lispector, utilizing psychoanalytic references...

El autor comenta el cuento Felicidad clandestina, de Clarice Lispector, utilizando referencial psicoanalítico...

Resgatando a Memória dos Patronos

O Patrono da Cadeira nº 3, Fernando de Azevedo, foi uma das personalidadesque mais se destacaram no campo educacional brasileiro durante o século XX. Esteve afrente de muitos movimentos culturais significativos articulando com mestria pensamentoe ação: como professor de Educação Física, filosofia, latim, psicologia e sociologia; comojornalista fazendo crítica literária e artigos educacionais; como educador ativista redigindoo Manifesto dos Pioneiros da Educação Nova, o Código de Educação, executando reformaseducacionais, participando da criação da Universidade de São Paulo; como pesquisadorrealizando Inquéritos, Censos, etc.; como executivo dirigindo uma editora; como escritorde grande número de obras e, ainda, como Titular da Academia Brasileira de Letras. Suaação continua dando frutos, como se pode ver na composição dessa Academia que,direta ou indiretamente, recebeu sua influência. Dos Acadêmicos, boa parte deles, foramseus alunos. Outros estudaram nos seus livros. O mesmo acontece com a plêiade depsicólogos brasileiros que, como ele, buscam sempre avançar no seu campo de atuaçãoatravés de pesquisas, de divulgação e de aplicação dos novos conhecimentos.Reconhecendo o seu valor, os fundadores da Academia Paulista de Psicologia ohomenagearam com o título de Patrono da Cadeira nº 3 atualmente ocupada pelo AcadêmicoCarlos Rolim Afonso. Contar o pouco que sei do muito que Fernando de Azevedo produziu,foi para mim, sua ex-aluna, um privilégio(AU)

Fernando de Azevedo, Patron of Chair number 3, was one of the most prominentpersonalities in the Brazilian educational field during the twentieth century. He was aleader of several significant cultural movements, linking together with mastery thought andaction: as a professor of Physical Education, Philosophy, Latin, Psychology and Sociology;as a journalist in literary criticism and educational articles; as an activist educator, developingthe Pioneers Manifest of the New Education, implementing educational changes,participating of the creation of the University of São Paulo; as a researcher performinginquiries, census, etc.; as an executive managing a publishing company; as a writer of agreat number of works and, furthermore, as a Member of the Brazilian Academy of Letters.His legacy continues very fruitful, as can be evaluated by the composition of this Academy,which was directly or indirectly influenced by him. A good part of the Academics were hispupils. Others studied by his books. The same thing happens with the selection of Brazilianpsychologists who, like himself, are always seeking to advance in their own fields, through researches, divulgation and application of new knowledge. In recognition of his values, thefounders of the APP have honored him with the title of Patron of Chair number 3, which ispresently occupied by Academic Carlos Rolim Afonso. To tell just a little of the enormityproduced by Fernando de Azevedo has been a privilege for me, his former pupil(AU)