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Artículo en Zh | WPRIM | ID: wpr-1039641

RESUMEN

As a public health event that seriously threatens human health, viral respiratory infectious diseases fall within the scope of "new illness entering collaterals". Collateral disease theory is used to guide prevention and treatment of this type of diseases, thus to propose the concept of infectious lung disease epidemic and reveal its progress rule of "Qi collaterals-Qi pathway-blood collaterals". By analyzing main therapeutic methods including detoxication, precipitation draining and aromatization, this paper proposes active intervention and treatment strategy of "simultaneously treating Wei and Qi, relieving exterior-interior syndrome, using medicine with evidence, stopping the disease tendency, overall adjustment and multi-target therapy". Through systematic summarization of historical medication regularity in infectious lung disease epidemic, this paper demonstrates that "maintaining healthy Qi" and "avoiding harmful Qi" are the general rules of prevention and treatment. Based on literature review, data mining and meta analysis of clinical experiences, this study inherits and innovatively develops the formula of Chinese patent medicine Lianhua Qingwen. The formula is developed through a modification to basic formulae Yinqiaosan and Maxing Shigantang. It learns from Wu Youke's experience in treating epidemic diseases with Rhei Radix et Rhizoma, considers pathological characteristics of infectious lung disease epidemic, and innovatively adds Rhodiolae Crenulatae Radix et Rhizoma and Pogostemonis Herba. The new formula is featured by clearing heat, being warm-pungent, function of both detoxication and aromatization, as well as simultaneous implementation of strengthening the body resistance and purging Fu organs. It can clear heat but won't over cool the body, keep the body warm but won't contribute to pathogenic fire, strengthening the body resistance but won't retain pathogen, and eliminate pathogen but won't damage healthy Qi. Meanwhile, series of basic and clinical studies have demonstrated that Lianhua Qingwen formula has the unique advantages for respiratory infectious diseases, which reveals the scientific connotation of infectious lung disease prevention and control under the guidance of pulmonary collateral disease diagnosis and treatment theory.

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