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Bioorg Med Chem Lett
; 20(19): 5772-5, 2010 Oct 01.
Artículo
en Inglés
| MEDLINE
| ID: mdl-20800481
RESUMEN
Design, synthesis and cytotoxicity of several known and novel biurets against human breast cancer T47D cell line in comparison to doxorubicin are described. Biurets incorporating 2-methyl quinoline-4-yl and benzo[d]thiazol-2-ylthio moieties showed higher cytotoxicity and decreased cell viability in a concentration- and time-dependent manner.