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1.
Molecules ; 29(6)2024 Mar 11.
Artículo en Inglés | MEDLINE | ID: mdl-38542876

RESUMEN

Endothelial inflammation is a multifaceted physiological process that plays a pivotal role in the pathogenesis and progression of diverse diseases, encompassing but not limited to acute lung infections like COVID-19, coronary artery disease, stroke, sepsis, metabolic syndrome, certain malignancies, and even psychiatric disorders such as depression. This inflammatory response is characterized by augmented expression of adhesion molecules and secretion of pro-inflammatory cytokines. In this study, we discovered that saponins from Allium macrostemon bulbs (SAMB) effectively inhibited inflammation in human umbilical vein endothelial cells induced by the exogenous inflammatory mediator lipopolysaccharide or the endogenous inflammatory mediator tumor necrosis factor-α, as evidenced by a significant reduction in the expression of pro-inflammatory factors and vascular cell adhesion molecule-1 (VCAM-1) with decreased monocyte adhesion. By employing the NF-κB inhibitor BAY-117082, we demonstrated that the inhibitory effect of SAMB on VCAM-1 expression may be attributed to the NF-κB pathway's inactivation, as characterized by the suppressed IκBα degradation and NF-κB p65 phosphorylation. Subsequently, we employed a murine model of lipopolysaccharide-induced septic acute lung injury to substantiate the potential of SAMB in ameliorating endothelial inflammation and acute lung injury in vivo. These findings provide novel insight into potential preventive and therapeutic strategies for the clinical management of diseases associated with endothelial inflammation.


Asunto(s)
Lesión Pulmonar Aguda , Cebollino , Medicamentos Herbarios Chinos , Saponinas , Humanos , Animales , Ratones , FN-kappa B/metabolismo , Molécula 1 de Adhesión Celular Vascular/genética , Molécula 1 de Adhesión Celular Vascular/metabolismo , Saponinas/farmacología , Lipopolisacáridos/toxicidad , Inflamación/tratamiento farmacológico , Inflamación/prevención & control , Células Endoteliales de la Vena Umbilical Humana , Factor de Necrosis Tumoral alfa/farmacología , Lesión Pulmonar Aguda/tratamiento farmacológico , Mediadores de Inflamación/metabolismo
2.
Zhongguo Zhong Yao Za Zhi ; 49(1): 232-242, 2024 Jan.
Artículo en Zh | MEDLINE | ID: mdl-38403356

RESUMEN

This study aimed at investigating the mechanism of Trichosanthis Fructus-Allii Macrostemonis Bulbus(GX) in treating cardiovascular diseases in rats with the syndrome of combined phlegm and stasis. The rat model was established by a high-fat diet, ice-water bath combined with subcutaneous injection of adrenalin hydrochloride, and the syndrome score was determined. The serum samples of rats in the control, model, and GX groups were collected. Ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry(UPLC-Q-TOF-MS) was employed to analyze the metabolic profiles of the serum samples. The differential metabolites were screened and identified by partial least squares-discriminant analysis(PLS-DA) and orthogonal partial least squares-discriminant analysis(OPLS-DA). The intervention targets of GX-regulated metabolites and their metabolic pathways were searched against MetaboAnalyst. Gene Ontology enrichment was carried out to predict the biological pathways associated with the intervention targets of metabolic pathways. A total of 129 potential biomarkers were detected in the rat model with the syndrome of combined phlegm and stasis via metabolomics, and GX regulated 54 metabolites in several metabolic pathways such as linoleic acid metabolism, sphingolipid metabolism, and tricarboxylic acid cycle. The further screening against MetaboAnalyst showed that GX recovered the levels of nine metabolites associated with cardiovascular diseases with the syndrome of combined phlegm and stasis, which involved 69 targets in the pathways regarding cholesterol metabolism, fatty acid metabolism, inflammatory response, and glucose homeostasis and metabolism. The above-mentioned results suggested that GX can alleviate the symptoms of the rat model of cardiovascular diseases with the syndrome of combined phlegm and stasis by regulating the metabolism of linoleic acid, sphingosine, docosahexaenoic acid, rosemary acid, succinic acid, adenine, L-phenylalanine, L-valine and modulating the biological pathways such as cholesterol metabolism, fatty acid metabolism, inflammatory response, and glucose homeostasis and metabolism.


Asunto(s)
Enfermedades Cardiovasculares , Cebollino , Medicamentos Herbarios Chinos , Ratas , Animales , Enfermedades Cardiovasculares/tratamiento farmacológico , Ácido Linoleico , Cromatografía Líquida de Alta Presión/métodos , Metabolómica/métodos , Biomarcadores , Colesterol , Glucosa
3.
Int J Biol Macromol ; 264(Pt 1): 130537, 2024 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-38432275

RESUMEN

This study aimed to investigate the structural characteristics, in vivo antiatherosclerosis activity, and in vitro myocardial injury protection effects of polysaccharides from Allium macrostemon Bunge and Allium chinense G. Don. Thus, crude polysaccharides of Allium macrostemon Bunge and Allium chinense G. Don significantly reduced serum lipid levels, improved cardiac myocyte morphology and arrangement, and relieved the development of myocardial fibrosis. Meanwhile, the lesion areas of the aorta and aortic valve had evident visual improvements. Furthermore, two main novel purified polysaccharides, namely, AMB-1 and ACGD-1, were isolated and characterized from crude Allium macrostemon Bunge and Allium chinense G. Don fractions, respectively. The purified polysaccharides mainly consisted of fructose and glucose and had molecular weights of 25.22 and 19.53 kDa, respectively. In addition, Fourier transform infrared spectroscopy, methylation, and nuclear magnetic resonance data revealed the primary structures of the AMB1 (or ACGD1) backbone with branched side chains. Scanning electron microscope analysis showed that the purified polysaccharides were both piled together in a lamellar or clastic form with a smooth surface along with linear or irregular bulges. Moreover, the purified polysaccharides both showed nontoxicity on H9c2 cells and effectively dropped hypoxia/reoxygenation-induced apoptosis by the BCL-2/BAX pathway. Overall, the characterization of the structural properties and in vivo and in vitro myocardial injury protection effects of Allium macrostemon Bunge and Allium chinense G. Don polysaccharides enriched our understanding of their nutritional and medicinal values. To the best of our knowledge, this is the first study on the structural characteristics and bioactivities of Allium chinense G. Don polysaccharides.


Asunto(s)
Cebollino , Cebollas , Polisacáridos , Espectroscopía de Resonancia Magnética , Polisacáridos/farmacología
4.
Pest Manag Sci ; 80(6): 2724-2737, 2024 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-38372475

RESUMEN

BACKGROUND: Chinese chives (Allium tuberosum Rottler ex Sprengel) are favored by consumers because of its delicious taste and unique fragrance. Bradysia odoriphaga (Diptera: Sciaridae) is a main pest that severely harms Chinese chives and other Liliaceae's production. Climate change may change the future distribution of B. odoriphaga in China. In this study, the CLIMEX was employed to project the potential distribution of B. odoriphaga in China, based on China's historical climate data (1987-2016) and forecast climate data (2021-2100). RESULTS: Bradysia odoriphaga distributed mainly between 19.8° N-48.3° N and 74.8° E-134.3° E, accounting for 73.25% of the total mainland area of China under historical climate conditions. Among them, the favorable and highly favorable habitats accounted for 30.64% of the total potential distribution. Under future climate conditions, B. odoriphaga will be distributed mainly between 19.8° N-49.3° N and 73.8° E-134.3° E, accounting for 84.89% of China's total mainland area. Among them, the favorable and highly favorable habitats will account for 35.23% of the total potential distribution, indicating an increase in the degree of fitness. Areas with relatively appropriate temperature and humidity will be more suitable for the survival of B. odoriphaga. Temperature was a more important determinant of the climatic suitability of the pest B. odoriphaga than humidity. Host plants (Liliaceae) availability also had impact on climate suitability in some regions. CONCLUSIONS: These projected potential distributions will provide supportive information for monitoring and early forecasting of pest outbreaks, and to reduce future economic and ecological losses. © 2024 Society of Chemical Industry.


Asunto(s)
Distribución Animal , Cambio Climático , Dípteros , Animales , China , Dípteros/fisiología , Cebollino , Ecosistema
5.
Biosci. j. (Online) ; 36(Supplement1): 192-204, Dec. 2020. tab
Artículo en Inglés | LILACS | ID: biblio-1355225

RESUMEN

Intercropping of vegetables in a poorly planned manner may not achieve the expected economic results, as it is an activity that requires a great technical and administrative capacity of the producer. This study aimed to analyze the economic feasibility of intercropping kale with coriander, lettuce, and chives in relation to monocultures. The experiment was conducted in the Center for Agri-food Science and Technology, Federal University of Campina Grande, in the municipality of Pombal, PB in the period from June 2014 to July 2015. Eleven treatments were tested: four polycultures, three bicultives, and four monocultures, in randomized blocks, with four replications. The productivity, total operating costs (TOC), gross and net revenue, rate of return, profitability index, and efficient land use were evaluated. The TOC values of intercropping were calculated with the prices of July 2015. In all the systems studied, the largest participation was referring to the cost hand of labor. The highest gross and net revenues were observed in the kale with lettuce in bicultive, the rate of return and profitability index was higher on lettuce in monoculture. Despite the increase in the TOCs of the intercropping in relation to the monocultures, the intercropping proved to be economically viable in terms of efficient land use, reaching values indicating a land-use efficiency of up to 50% more in polycultures and bicultives.


O cultivo de hortaliças de maneira mal planejada pode não alcançar os resultados econômicos esperados, pois é uma atividade que exige grande capacidade técnica e administrativa do produtor. O objetivo deste estudo foi avaliar a viabilidade econômica de cultivar couve, alface e cebolinha em consórcio. O experimento foi conduzido no Centro de Ciência e Tecnologia Agroalimentar da Universidade Federal de Campina Grande, no município de Pombal, PB, no período de junho de 2014 a julho de 2015. Foram testados onze tratamentos: quatro policultivos, três bicultivos e quatro monocultivos, em blocos casualizados, com quatro repetições. Foram avaliados: produtividade; custos operacionais totais (COT); receita bruta e líquida; taxa de retorno; índice de lucratividade e uso eficiente da terra (UET). Os valores de COT do consórcio foram calculados com os preços de julho de 2015. Em todos os sistemas estudados, a maior participação foi referente ao custo mão de obra. As maiores receita bruta e líquida foram observadas na couve com alface em bicultivo, a taxa de retorno e rentabilidade índice foram maiores na alface em monocultura. Apesar do aumento nos COT'S dos consórcios em relação às monoculturas, a consorciação mostrou-se economicamente viável em termos de uso eficiente da terra, alcançando valores que indicam uma eficiência no uso da terra de até 50% a mais em policultivos e bicultivos.


Asunto(s)
Brassica , Lactuca , Productos Agrícolas/economía , Coriandrum , Cebollino
6.
Biosci. j. (Online) ; 35(3): 796-805, may./jun. 2019. tab, graf
Artículo en Inglés | LILACS | ID: biblio-1048657

RESUMEN

The cultivation of vegetables in semi-arid regions, especially in the context of the use of brackish water, has been made possible by the use of the hydroponics technique. Thus, two experiments were carried out between December 2016 and January 2017 in a protected environment at the Federal Rural University of Pernambuco (UFRPE), Recife ­ PE, Brazil (8° 1"7" South latitude and 34° 56" 53" West longitude, and average altitude of 6.5 m), aiming at evaluating the production of green onion (cv. "Todo dia" Evergreen - Nebuka) in plants exposed to brackish nutrient solution (1.5, 3.0, 4.5, 6.0, 7.5 and 9.0 dS m-1), applied at two frequencies of circulation (twice a day - at 8 and 16 hours, and three times per day - at 8, 12 and 16 hours) in low-cost hydroponics system. In Experiment I, the nutrient solution evapotranspirated by the plants was replaced with the respective brackish water used in its preparation, and in Experiment II with UFRPE supply water (0.12 dS m-1). In both cases, a completely randomized experimental design was used, in a 6 x 2 factorial scheme, with five replications. It was concluded that under replacement with brackish water, the increase in the frequency of circulation attenuated the losses imposed by the salinity to the biometric variables and of the production of fresh and dry phytomass of the plants; the water supply replenishment had a greater mitigating role in relation to the damage caused by the salinity with the increase of the electrical conductivity of the nutrient solution.


O cultivo de hortaliças em regiões semiáridas, especialmente no contexto de uso de águas salobras, tem sido viabilizado pelo uso da técnica da hidroponia. Diante disto, entre janeiro de 2016 e abril de 2017, foram conduzidos dois experimentos em ambiente protegido na Universidade Federal Rural de Pernambuco (UFRPE), Recife, PE (8° 1"7" Sul e 34° 56" 53" Oeste, altitude média de 6,5 m), objetivando-se avaliar a produção da cebolinha (cv. Todo ano Evergreen - Nebuka) em plantas expostas a soluções nutritivas salobras (1,5; 3,0; 4,5; 6,0; 7,5 e 9,0 dS m-1) aplicadas em duas frequências de circulação (duas vezes ao dia - às 8 e às 16 horas; e três vezes ao dia - às 8, 12 e 16 horas). Em ambos os casos, utilizou-se um delineamento experimental inteiramente casualizado, em esquema fatorial 6 x 2, com cinco repetições. No Experimento I, a lâmina de solução nutritiva evapotranspirada pelas plantas foi reposta com a respectiva água salobra utilizada no seu preparo e, no Experimento II, com água de abastecimento da UFRPE (0,12 dS m-1). Concluiu-se que sob reposição com água salobra, o aumento da frequência de circulação atenuou as perdas impostas pela salinidade às variáveis biométricas e de produção de fitomassa fresca e seca das plantas; a reposição com água deabastecimento passou a ter maior papel mitigador em relação ao dano causado pela salinidade com o aumento da condutividade elétrica da solução nutritiva.


Asunto(s)
Verduras , Hidroponía , Cebollino , Salinidad , Zona Semiárida
7.
Rev. toxicol ; 35(2): 112-118, 2018. tab, graf
Artículo en Español | IBECS (España) | ID: ibc-176873

RESUMEN

Los fármacos son considerados dentro de los llamados contaminantes emergentes, por lo que es importante investigar los efectos tóxicos que pueden producir en el medio ambiente. Este estudio tuvo como objetivos determinar el efecto tóxico de soluciones acuosas de ibuprofeno sobre un organismo acuático Artemia salina y las semillas de Allium schoenoprasum L y Lactuca sativa. Los ensayos de toxicidad se llevaron a cabo exponiendo a los organismos de prueba a concentraciones de soluciones acuosas de ibuprofeno de 20, 10, 5, 2, 1 y 0.5 mgL-1. Se determinó el porcentaje de mortalidad para la Artemia salina y la elongación de la radícula e hipocótilo para las semillas. El porcentaje de mortalidad más elevado se presentó a la concentración de 20 mgL-1, la CL50 calculada fue de 17.386 mgL-1. Un efecto tóxico bajo se presentó en la germinación de las semillas de Allium schoenoprasum L. Se produjo la inhibición en la elongación de la radícula e hipocótilo en semillas de Allium schoenoprasum L y un efecto de estimulación en la elongación de la radícula e hipocótilo de las semillas de Lactuca sativa. El mayor efecto de inhibición se presentó a 1 y 20 mgL-1 y la mayor estimulación a 20 mgL-1


Drugs are considered within the so-called emerging pollutants, so it is important to investigate the toxic effects they can produce in the environment. The aim of this study was to determine the toxic effect of aqueous solutions of ibuprofen on an aquatic organism Artemia salina and the seeds of Allium schoenoprasum L and Lactuca sativa. The toxicity tests were carried out by exposing the test organisms to concentrations of aqueous ibuprofen solutions of 20, 10, 5, 2, 1 and 0.5 mgL-1. The percentage of mortality for Artemia salina and the elongation of the radicle and hypocotyl for the seeds were determined. The highest mortality percentage occurred at the concentration of 20 mgL-1, the calculated LC50 was 17.386 mgL-1. A low toxic effect was present in the germination of the seeds of Allium schoenoprasum L. There was inhibition in the elongation of the radicle and hypocotyl in seeds of Allium schoenoprasum L and a stimulation effect in the elongation of the radicle and hypocotyl of the seeds of Lactuca sativa. The highest inhibition effect was presented at 1 and 20mgL-1 and the highest stimulation at 20 mgL-1


Asunto(s)
Ibuprofeno/toxicidad , Artemia , Cebollino , Lactuca , Pruebas de Toxicidad/métodos , Bioensayo/estadística & datos numéricos , Semillas/crecimiento & desarrollo , Semillas
8.
Artículo en Inglés | WPRIM | ID: wpr-50090

RESUMEN

Cryptosporidium and Cyclospora are well-known coccidian protozoa that can cause waterborne and foodborne diarrheal illnesses. There have been a few reports regarding contamination in different vegetables with Cryptosporidium, but no data are available regarding the sources of Cyclospora infections in Korea. In the present study, we collected 6 kinds of vegetables (perilla leaves, winter-grown cabbages, chives, sprouts, blueberries, and cherry tomatoes) from July 2014 to June 2015, and investigated contamination by these 2 protozoa using multiplex quantitative real-time PCR. Among 404 vegetables, Cryptosporidium and Cyclospora were detected in 31 (7.7%) and 5 (1.2%) samples, respectively. In addition, Cryptosporidium was isolated from all 6 kinds of vegetables, whereas Cyclospora was detected in 4 kinds of vegetables (except perilla leaves and chives). Cryptosporidium (17.8%) and Cyclospora (2.9%) had the highest detection rates in chives and winter-grown cabbages, respectively. Cryptosporidium was detected all year long; however, Cyclospora was detected only from October to January. In 2 samples (sprout and blueberry), both Cryptosporidium and Cyclospora were detected. Further investigations using TaqI restriction enzyme fragmentation and nested PCR confirmed Cryptosporidium parvum and Cyclospora cayetanensis, respectively. In conclusion, we detected C. cayetanensis in vegetables for the first time in Korea. This suggests that screening should be employed to prevent these protozoal infections in Korea.


Asunto(s)
Arándanos Azules (Planta) , Brassica , Cebollino , Cryptosporidium parvum , Cryptosporidium , Cyclospora , Corea (Geográfico) , Tamizaje Masivo , Perilla , Reacción en Cadena de la Polimerasa , Reacción en Cadena en Tiempo Real de la Polimerasa , Verduras
9.
Artículo en Inglés | WPRIM | ID: wpr-113437

RESUMEN

BACKGROUND: Endothelial adhesion molecule expression induced by pro-inflammatory cytokine plays an important role in vascular endothelial cell injury, leading to vascular disease. Allium tuberosum (AT), which is used as a functional food, has a thrombolytic effect. It contains vitamin A, vitamin C, carbohydrate, calcium, iron, and phosphorus. There are many carotenes that turn into vitamin A in the body. Also, it helps blood circulation and stimulates metabolism. The purpose of the this study was to estimate the anti-inflammatory effects of the AT extract. METHODS: Human vascular endothelial cells were pre-treated with 100 μg/mL AT extract for 30 minutes and subsequently co-treated with TNF-α (10 ng/mL) and AT extract (100 μg/mL) for 1, 4, and 6 hours. After treatment, the cells were lysed and used for quantitative reverse transcription PCR, Western blot analysis, and monocyte adhesion assay. RESULTS: We examined the effect of the AT extract on inflammatory gene expression in TNF-α-induced human umbilical vein endothelial cells (HUVECs). The extract reduced the expression levels of mRNA and protein of intercellular adhesion molecule (ICAM)-1 and vascular cell adhesion molecule (VCAM)-1 in TNF-α-stimulated HUVECs. It also inhibited the TNF-α-induced phosphorylation of the NF-κB p65 subunit and degradation of IκBα. Furthermore, the AT extract prevented the increased adhesion capacity of monocyte to TNF-α-stimulated vascular endothelial cells by reducing ICAM-1 and VCAM-1 expression. CONCLUSIONS: The AT extract has preventive and anti-inflammatory effect against vascular disease and has potential for supporting prevention against the early process of atherosclerosis.


Asunto(s)
Humanos , Allium , Ácido Ascórbico , Aterosclerosis , Circulación Sanguínea , Western Blotting , Calcio , Carotenoides , Cebollino , Células Endoteliales , Alimentos Funcionales , Expresión Génica , Células Endoteliales de la Vena Umbilical Humana , Inflamación , Molécula 1 de Adhesión Intercelular , Hierro , Metabolismo , Monocitos , Necrosis , FN-kappa B , Fósforo , Fosforilación , Reacción en Cadena de la Polimerasa , Transcripción Reversa , ARN Mensajero , Molécula 1 de Adhesión Celular Vascular , Enfermedades Vasculares , Vitamina A
10.
Bol. latinoam. Caribe plantas med. aromát ; 10(3): 218-221, mayo 2011. ilus, tab
Artículo en Inglés | LILACS | ID: lil-687010

RESUMEN

Essential oil from leaves and roots of Allium schoenoprasum L. (Alliaceae) were analyzed by GC/MS. The oils extracted by hydrodistillation yielded 0.02 percent and 0.03 percent for leaves and roots, respectively. Five (99.12 percent leaves) and four (98.32 percent roots) components were identified being bis-(2-sulfhydryethyl)-disulfide (72.06 percent leaves, 56.47 percent roots) the major constituent on the two oil samples while 2,4,5-trithiahexane (5.45 percent leaves, 15.90 percent roots) and tris (methylthio)-methane (4.01 percent leaves, 12.81 percent roots) were detected in lower amounts.


Los aceites esenciales de hojas y raíces de Allium schoenoprasum L. (Alliaceae fueron analizados por CG/EM. La extracción por hidrodestilación mostró un rendimiento de 0.02 por ciento y 0.03 por ciento para las hojas y raíces, respectivamente. Cinco (99.12 por ciento hojas) y cuatro (98.32 por ciento raíces) compuestos fueron identificados siendo el bis-(2-sulfidietil)-disulfuro (72.06 por ciento hojas, 56.47 por ciento raíces) el compuesto mayoritario en los dos aceites mientras que 2,4,5-tritiahexano (5.45 por ciento hojas, 15.90 por ciento raíces) y tris (metilthio)-metano (4.01 por ciento hojas, 12.81 por ciento raíces) fueron observados en menores cantidades.


Asunto(s)
Aceites Volátiles/química , Cebollino/química , Hojas de la Planta/química , Sulfuros/análisis , Cromatografía de Gases y Espectrometría de Masas , Hexanos/análisis , Metano/análisis , Raíces de Plantas/química
11.
Mycobiology ; : 230-232, 2011.
Artículo en Inglés | WPRIM | ID: wpr-729514

RESUMEN

In this study, we characterized sporadically occurring sclerotium rot caused by Sclerotium rolfsii in Chinese chive (Allium tuberosum Roth.) in farm fields in Sacheon, Korea. The initial symptom of the disease was water-soaked, which progressed to rotting, wilting, blighting, and eventually death. Further, mycelial mats spread over the lesions near the soil line, and sclerotia formed on the scaly stem and leaves. The sclerotia were globoid, 1~3 mm, and white to brown. The optimum temperature for growth and sclerotia formation on potato dextrose agar (PDA) was 30degrees C. The diameter of the hypae ranged from 4 to 8 microm. Clamp connection was observed on PDA medium after 5 days of incubation. Based on the mycological characteristics, internal transcribed spacer sequence analysis, and pathogenicity test, the causal agent was identified as Sclerotium rolfsii Saccardo. This is the first report of sclerotium rot in Chinese chive caused by S. rolfsii in Korea.


Asunto(s)
Humanos , Agar , Allium , Compuestos Alílicos , Cebollino , Glucosa , Corea (Geográfico) , Análisis de Secuencia , Suelo , Solanum tuberosum , Sulfuros
12.
Mycobiology ; : 72-76, 2009.
Artículo en Inglés | WPRIM | ID: wpr-729204

RESUMEN

To investigate the growth response of various crop species to mycorrhizal inoculation, arbuscular mycorrhizal fungi were applied to Glycine max, Vigna angularis, Senna tora, Hordeum vulgare var. hexastichon. Zea mays, Sorghum bicolor, Allium tuberosum, Solanum melongena, and Capsicum annuum. The biomass of the inoculated crops was measured every two weeks for the 12-week growth period. By measuring biomass, we calculated the mycorrhizal responsiveness of the nine crop species. Among the nine crop species, four species showed a significant response to mycorrhizal inoculation. The shoot biomasses of V. angularis, C. annuum, A. tuberosum, and S. tora significantly increased with mycorrhizal inoculation.


Asunto(s)
Biomasa , Capsicum , Cebollino , Hongos , Hordeum , Solanum melongena , Sorghum , Glycine max , Zea mays
13.
Artículo en Ko | WPRIM | ID: wpr-645742

RESUMEN

The effects of Allium vegetables on blood glucose levels and lipid metabolism in streptozotocin (STZ) induced diabetic rats were investigated. Diabetes mellitus was induced by STZ injection (45 mg/kg b.w.) into the tail vein. Sprague-Dawley rats weighing 220+/-10 g were randomly assigned to 7 groups: normal, STZ-control and five Allium groups (Allium cepa, Allium fistulosum, Allium sativum, Allium tuberosum and Allium victorialis) . Normal and STZ-control groups were fed an AIN-93 diet and five Allium groups were fed a modified diet containing 10% Allium powder each for 4 weeks. Body weight, diet intake, food efficiency ratio (FER) and organ weights were monitored. Activities of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) were observed. Plasma levels of glucose, free fatty acid, triglyceride and HDL-cholesterol were analyzed. Levels of glycogen, cholesterol and triglyceride in liver were determined. Levels of malondialdehyde (MDA) in liver, lung, kidney, and pancreas were assayed. The hepatic contents of chromium (Cr) , iron (Fe) , zinc (Zn) and manganese (Mn) were measured. The Allium sativum group had weight gain and suppressed a hypertrophy of the kidney significantly. The activity of ALT was significantly lowered in the diabetic groups except Allium sativum group compared to STZ-control group. The Allium sativum and Allium tuberosum groups showed the hypoglycemic effects at 4 weeks. There were no significant differences between the control and all the other diabetic groups in the plasma levels of cholesterol, HDL-cholesterol, triglycerides and free fatty acids. Most of the Allium groups except Allium fistulosum were observed significantly lowered level of MDA in the lung compared to STZ-control group. The diabetic rats fed the Allium cepa and Allium sativum have shown significantly lowered hepatic Zn contents. The results suggested that the intake of the Allium vegetables may be effective in the antihyperglycemia by lowering blood glucose levels.


Asunto(s)
Animales , Ratas , Alanina Transaminasa , Allium , Aspartato Aminotransferasas , Glucemia , Peso Corporal , Cebollino , Colesterol , Cromo , Diabetes Mellitus , Dieta , Ingestión de Alimentos , Ácidos Grasos no Esterificados , Ajo , Glucosa , Glucógeno , Hipertrofia , Hipoglucemiantes , Hierro , Riñón , Metabolismo de los Lípidos , Hígado , Pulmón , Malondialdehído , Manganeso , Minerales , Cebollas , Tamaño de los Órganos , Páncreas , Plasma , Ratas Sprague-Dawley , Estreptozocina , Triglicéridos , Verduras , Venas , Aumento de Peso , Zinc
14.
Artículo en Zh | WPRIM | ID: wpr-358035

RESUMEN

<p><b>OBJECTIVE</b>To explore the effect of extract from Chinese chive seed in warming kidney and enhancing yang.</p><p><b>METHOD</b>The influence of extract from Chinese chive seed on the erection of penis of was investigated in adult male rats with experimental insufficiency of the kidney-yang produced by both removal of double spermaries and high dose of hydrocortisone.</p><p><b>RESULT</b>The extract of Chinese chive seed enhanced the responsiveness of the penis of emasculate rats to outside stimulus, promoted the resistance of the emasculated rats to cold and tiredness and increased autonomous activity.</p><p><b>CONCLUSION</b>The extract of Chinese chive seed has the effect of warming kidney and enhancing yang.</p>


Asunto(s)
Animales , Masculino , Ratones , Ratas , Cebollino , Química , Frío , Medicamentos Herbarios Chinos , Farmacología , Fatiga , Hidrocortisona , Enfermedades Renales , Actividad Motora , Orquiectomía , Erección Peniana , Plantas Medicinales , Química , Ratas Wistar , Semillas , Química , Deficiencia Yang
15.
Rev. iberoam. micol ; 25(3): 193-195, 2008. ilus
Artículo en Español | IBECS (España) | ID: ibc-75046

RESUMEN

Conidiobolus coronatus, entomoftoral patógeno para el hombre y algunosinsectos, se aisló a partir de especímenes muertos del áfido Neotoxopteraformosana sobre hojas de Allium schoenoprasum. La presencia deC. coronatus supone el riesgo de una potencial infección para quienestrabajan en la producción de cebollín. El control fitosanitario de N. formosanapodría, además, contribuir a reducir el riesgo de infección humana conC. coronatus(AU)


Conidiobolus coronatus (Entomophthorales), a pathogen of human and someinsects, was isolated from dead specimens of the aphid Neotoxopteraformosana present on chives leaves. C. coronatus infected aphids could posea threat to growers health. Pest control strategies of N. formosana may alsocontribute to reduce the human infection risk by C. coronatus(AU)


Asunto(s)
Conidiobolus/aislamiento & purificación , Áfidos/patogenicidad , Cebollino/microbiología , Enfermedades de las Plantas/microbiología , Entomophthorales/aislamiento & purificación , Cigomicosis/microbiología , Control Biológico de Vectores
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