RESUMEN
A case of strumal carcinoid of the ovary is reported. The follicles contained T4-immunoreactive substance, whereas the carcinoid component of the tumor had a trabecular structure and showed argyrophilic elements. Pancreatic-polypeptide and enteroglucagon were localized in these cells by an immunocytochemical method. The same cells displayed small electron-dense endocrine-like granules. A common precursor for the thyroid and carcinoid components is postulated.
Asunto(s)
Tumor Carcinoide/inmunología , Neoplasias Ováricas/inmunología , Estruma Ovárico/inmunología , Tumor Carcinoide/metabolismo , Tumor Carcinoide/ultraestructura , Femenino , Histocitoquímica , Humanos , Microscopía Electrónica , Persona de Mediana Edad , Neoplasias Ováricas/metabolismo , Neoplasias Ováricas/ultraestructura , Estruma Ovárico/metabolismo , Estruma Ovárico/ultraestructura , Tiroxina/inmunologíaRESUMEN
BACKGROUND: Struma ovarii, presenting as pseudo-Meigs' syndrome with an elevated CA 125 level, is a rare condition. CASE: A 65-year-old patient presented with ascites, hydrothorax, right ovarian mass, and elevated CA 125 level. These findings were suspicious for an ovarian malignancy. The mass was removed and revealed struma ovarii, a specialized ovarian teratoma composed predominantly of mature thyroid tissue. In the setting of ascites and hydrothorax, the condition is known as pseudo-Meigs' syndrome. This is the second reported case in the English language literature of pseudo-Meigs' syndrome with an elevated CA 125 level resulting from struma ovarii. CONCLUSION: Struma ovarii is a rare cause of ascites, hydrothorax, and an elevated CA 125 level.