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Photodiagnosis Photodyn Ther ; 13: 323-329, 2016 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-26369605

RESUMEN

OBJECTIVES: The aim of this study was to evaluate whether a new method using quantitative light-induced fluorescence-digital (QLF-D) was appropriate for the diagnosis of oral malodor by quantifying the fluorescence of tongue coating. METHODS: This study examined 103 healthy subjects who have an oral malodor as a main complaint. The levels of oral malodor were measured by organoleptic scores (OLS) and volatile sulfur compound (VSC) levels. The fluorescent tongue coating images captured by QLF-D were quantified as the integrated fluorescence score (IF score) by multiplying the intensity and area of fluorescence. The correlations between the fluorescence parameters and OLS as well as VSC levels and the diagnostic accuracy of the IF score were evaluated. RESULTS: The IF score of tongue coating showed a significant positive correlation with the OLS (r=0.54, p<0.01) and the VSC levels (r=0.49, p<0.01). This score was significantly differed with the level of oral malodor (p<0.001), and its AUC was 0.72 in identifying the patient with definite oral malodor (≥OLS 2). CONCLUSIONS: A new method quantifying tongue coating fluorescence detected by QLF-D can be used to diagnose oral malodor and assess its severity in the clinical practice.


Asunto(s)
Pruebas Respiratorias/métodos , Halitosis/diagnóstico por imagen , Imagen Óptica/métodos , Lengua/efectos de los fármacos , Lengua/diagnóstico por imagen , Adulto , Anciano , Biomarcadores/análisis , Femenino , Halitosis/metabolismo , Humanos , Masculino , Persona de Mediana Edad , Odorantes/análisis , Reproducibilidad de los Resultados , Sensibilidad y Especificidad , Lengua/química , Adulto Joven
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