RESUMEN
A case of papillary adenoma of type 2 pneumocytes is reported. A 57-year-old man had an unusual coin lesion in the periphery of the right lung without any symptoms. When detected in a mass survey examination, it was approximately 1.5 cm in diameter, well circumscribed, and located in S4, involving the sixth-order bronchus of B4. Light-microscopic examination revealed cuboidal tumor cells arranged in a papillary pattern. Ultrastructurally, the cells had characteristic osmiophilic lamellar bodies. By immunoperoxidase staining, the tumor cells were shown to have intracytoplasmic surfactant apoproteins. The postoperative course was uneventful, and there is no evidence of disease 8 years later.
Asunto(s)
Cistoadenoma/patología , Pulmón/patología , Nódulo Pulmonar Solitario/patología , Cistoadenoma/análisis , Humanos , Técnicas para Inmunoenzimas , Cuerpos de Inclusión/ultraestructura , Neoplasias Pulmonares/análisis , Neoplasias Pulmonares/patología , Masculino , Microscopía Electrónica , Persona de Mediana Edad , Nódulo Pulmonar Solitario/análisisRESUMEN
A case of a benign clear cell ('sugar') tumour of the lung in a 61-year-old woman is presented. Characteristic routine histological features are provided and problems concerning differential diagnosis are discussed. Immunohistochemical stainings for the intracytoplasmatic intermediate filament proteins keratin and vimentin in our patient suggest a mesenchymal origin for this rare pulmonary neoplasm, and provide useful diagnostic aid in inconclusive cases.