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1.
Nature ; 573(7774): 385-389, 2019 09.
Artículo en Inglés | MEDLINE | ID: mdl-31485075

RESUMEN

Phase transitions are driven by collective fluctuations of a system's constituents that emerge at a critical point1. This mechanism has been extensively explored for classical and quantum systems in equilibrium, whose critical behaviour is described by the general theory of phase transitions. Recently, however, fundamentally distinct phase transitions have been discovered for out-of-equilibrium quantum systems, which can exhibit critical behaviour that defies this description and is not well understood1. A paradigmatic example is the many-body localization (MBL) transition, which marks the breakdown of thermalization in an isolated quantum many-body system as its disorder increases beyond a critical value2-11. Characterizing quantum critical behaviour in an MBL system requires probing its entanglement over space and time4,5,7, which has proved experimentally challenging owing to stringent requirements on quantum state preparation and system isolation. Here we observe quantum critical behaviour at the MBL transition in a disordered Bose-Hubbard system and characterize its entanglement via its multi-point quantum correlations. We observe the emergence of strong correlations, accompanied by the onset of anomalous diffusive transport throughout the system, and verify their critical nature by measuring their dependence on the system size. The correlations extend to high orders in the quantum critical regime and appear to form via a sparse network of many-body resonances that spans the entire system12,13. Our results connect the macroscopic phenomenology of the transition to the system's microscopic structure of quantum correlations, and they provide an essential step towards understanding criticality and universality in non-equilibrium systems1,7,13.


Asunto(s)
Modelos Teóricos , Teoría Cuántica , Partículas Elementales , Termodinámica
2.
Nature ; 601(7891): 32-33, 2022 01.
Artículo en Inglés | MEDLINE | ID: mdl-34987211
3.
Nature ; 589(7843): 518-519, 2021 01.
Artículo en Inglés | MEDLINE | ID: mdl-33505031
4.
Nature ; 590(7847): 559-560, 2021 02.
Artículo en Inglés | MEDLINE | ID: mdl-33627805
6.
Nature ; 599(7886): 560-561, 2021 11.
Artículo en Inglés | MEDLINE | ID: mdl-34819686
7.
Proc Jpn Acad Ser B Phys Biol Sci ; 97(5): 211-235, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33980753

RESUMEN

The history concerning an experimental verification of the standard model of particle physics is reviewed with special emphasis on results from experiments using the highest-energy particle colliders, namely, PETRA, LEP and LHC. This article covers physics subjects from discovering the gluon and precise measurements at LEP, to discovering the Higgs boson. It also covers some searches for physics beyond the standard model, particularly supersymmetry, as well as recent developments of some particle detectors that were used in those experiments.


Asunto(s)
Partículas Elementales , Modelos Teóricos , Interpretación Estadística de Datos , Historia del Siglo XX , Historia del Siglo XXI , Método de Montecarlo , Física Nuclear , Aceleradores de Partículas
8.
Proc Jpn Acad Ser B Phys Biol Sci ; 96(6): 204-233, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-32522939

RESUMEN

In the standard model of elementary particle physics neutrinos are massless, and therefore the actuality of finite neutrino mass indicates a theory beyond the standard model. The Sun produces abundant neutrinos due to nuclear fusion reactions. A pioneering experiment in the early '70s detected neutrinos from the Sun, but found that the observed flux was smaller than expected, which was then called the missing solar neutrino problem. Tremendous efforts were made both experimentally and theoretically to solve this problem. In 2001, almost 30 years after the first indication, data from Super-Kamiokande in Japan and SNO in Canada together provided evidence that neutrino oscillation effectively converts the solar (electron) neutrinos to non-electron type neutrinos. Neutrino oscillation can occur only for those neutrinos with finite neutrino mass.


Asunto(s)
Partículas Elementales , Fenómenos Físicos , Sistema Solar
9.
Nature ; 557(7704): 171-172, 2018 05.
Artículo en Inglés | MEDLINE | ID: mdl-29740137
10.
Nature ; 558(7710): 375-376, 2018 06.
Artículo en Inglés | MEDLINE | ID: mdl-29925972
11.
Nature ; 544(7648): 38-39, 2017 04 05.
Artículo en Inglés | MEDLINE | ID: mdl-28382992
12.
Nature ; 546(7657): 185-186, 2017 06 07.
Artículo en Inglés | MEDLINE | ID: mdl-28593976
13.
Int J Mol Sci ; 19(2)2018 Feb 07.
Artículo en Inglés | MEDLINE | ID: mdl-29414878

RESUMEN

Suberoylanilide hydroxamic acid (SAHA) is a histone deacetylase inhibitor, which has been widely utilized throughout the cancer research field. SAHA-induced radiosensitization in normal human fibroblasts AG1522 and lung carcinoma cells A549 were evaluated with a combination of γ-rays, proton, and carbon ion exposure. Growth delay was observed in both cell lines during SAHA treatment; 2 µM SAHA treatment decreased clonogenicity and induced cell cycle block in G1 phase but 0.2 µM SAHA treatment did not show either of them. Low LET (Linear Energy Transfer) irradiated A549 cells showed radiosensitization effects on cell killing in cycling and G1 phase with 0.2 or 2 µM SAHA pretreatment. In contrast, minimal sensitization was observed in normal human cells after low and high LET radiation exposure. The potentially lethal damage repair was not affected by SAHA treatment. SAHA treatment reduced the rate of γ-H2AX foci disappearance and suppressed RAD51 and RPA (Replication Protein A) focus formation. Suppression of DNA double strand break repair by SAHA did not result in the differences of SAHA-induced radiosensitization between human cancer cells and normal cells. In conclusion, our results suggest SAHA treatment will sensitize cancer cells to low and high LET radiation with minimum effects to normal cells.


Asunto(s)
Inhibidores de Histona Desacetilasas/farmacología , Ácidos Hidroxámicos/farmacología , Neoplasias/radioterapia , Fármacos Sensibilizantes a Radiaciones/farmacología , Células A549 , Biomarcadores de Tumor/análisis , Ciclo Celular/efectos de los fármacos , Proliferación Celular/efectos de los fármacos , Supervivencia Celular/efectos de los fármacos , Roturas del ADN de Doble Cadena/efectos de los fármacos , Reparación del ADN/efectos de los fármacos , Partículas Elementales/uso terapéutico , Fibroblastos/efectos de los fármacos , Rayos gamma/uso terapéutico , Inhibidores de Histona Desacetilasas/efectos adversos , Humanos , Ácidos Hidroxámicos/efectos adversos , Fotones/uso terapéutico , Fármacos Sensibilizantes a Radiaciones/efectos adversos , Vorinostat
14.
Nature ; 539(7627): 40-41, 2016 11 03.
Artículo en Inglés | MEDLINE | ID: mdl-27808202
15.
Proc Natl Acad Sci U S A ; 111(21): 7527-30, 2014 May 27.
Artículo en Inglés | MEDLINE | ID: mdl-24821773

RESUMEN

Dynamic nuclear polarization (DNP), a means of transferring spin polarization from electrons to nuclei, can enhance the nuclear spin polarization (hence the NMR sensitivity) in bulk materials at most 660 times for (1)H spins, using electron spins in thermal equilibrium as polarizing agents. By using electron spins in photo-excited triplet states instead, DNP can overcome the above limit. We demonstrate a (1)H spin polarization of 34%, which gives an enhancement factor of 250,000 in 0.40 T, while maintaining a bulk sample (∼ 0.6 mg, ∼ 0.7 × 0.7 × 1 mm(3)) containing >10(19) (1)H spins at room temperature. Room temperature hyperpolarization achieved with DNP using photo-excited triplet electrons has potentials to be applied to a wide range of fields, including NMR spectroscopy and MRI as well as fundamental physics.


Asunto(s)
Partículas Elementales , Campos Magnéticos , Espectroscopía de Resonancia Magnética/métodos , Modelos Químicos , Temperatura , Termodinámica
16.
Proc Natl Acad Sci U S A ; 111(11): 3973-8, 2014 Mar 18.
Artículo en Inglés | MEDLINE | ID: mdl-24591647

RESUMEN

Understanding the coupled electronic and nuclear dynamics in molecules by using pump-probe schemes requires not only the use of short enough laser pulses but also wavelengths and intensities that do not modify the intrinsic behavior of the system. In this respect, extreme UV pulses of few-femtosecond and attosecond durations have been recognized as the ideal tool because their short wavelengths ensure a negligible distortion of the molecular potential. In this work, we propose the use of two twin extreme UV pulses to create a molecular interferometer from direct and sequential two-photon ionization processes that leave the molecule in the same final state. We theoretically demonstrate that such a scheme allows for a complete identification of both electronic and nuclear phases in the wave packet generated by the pump pulse. We also show that although total ionization yields reveal entangled electronic and nuclear dynamics in the bound states, doubly differential yields (differential in both electronic and nuclear energies) exhibit in addition the dynamics of autoionization, i.e., of electron correlation in the ionization continuum. Visualization of such dynamics is possible by varying the time delay between the pump and the probe pulses.


Asunto(s)
Partículas Elementales , Rayos Láser , Microscopía de Interferencia/métodos , Modelos Químicos , Rayos Ultravioleta , Factores de Tiempo
17.
Phys Rev Lett ; 116(14): 141802, 2016 04 08.
Artículo en Inglés | MEDLINE | ID: mdl-27104699

RESUMEN

We show that by adding a single new scalar particle to the standard model, a TeV-scale leptoquark with the quantum numbers of a right-handed down quark, one can explain in a natural way three of the most striking anomalies of particle physics: the violation of lepton universality in B[over ¯]→K[over ¯]ℓ^{+}ℓ^{-} decays, the enhanced B[over ¯]→D^{(*)}τν[over ¯] decay rates, and the anomalous magnetic moment of the muon. Constraints from other precision measurements in the flavor sector can be satisfied without fine-tuning. Our model predicts enhanced B[over ¯]→K[over ¯]^{(*)}νν[over ¯] decay rates and a new-physics contribution to B_{s}-B[over ¯]_{s} mixing close to the current central fit value.


Asunto(s)
Partículas Elementales , Modelos Teóricos , Física Nuclear/métodos
18.
Phys Rev Lett ; 116(5): 053001, 2016 Feb 05.
Artículo en Inglés | MEDLINE | ID: mdl-26894707

RESUMEN

We present spectroscopy of a single Rydberg atom excited within a Bose-Einstein condensate. We not only observe the density shift as discovered by Amaldi and Segrè in 1934, but a line shape that changes with the principal quantum number n. The line broadening depends precisely on the interaction potential energy curves of the Rydberg electron with the neutral atom perturbers. In particular, we show the relevance of the triplet p-wave shape resonance in the e^{-}-Rb(5S) scattering, which significantly modifies the interaction potential. With a peak density of 5.5×10^{14} cm^{-3}, and therefore an interparticle spacing of 1300 a_{0} within a Bose-Einstein condensate, the potential energy curves can be probed at these Rydberg ion-neutral atom separations. We present a simple microscopic model for the spectroscopic line shape by treating the atoms overlapped with the Rydberg orbit as zero-velocity, uncorrelated, pointlike particles, with binding energies associated with their ion-neutral separation, and good agreement is found.


Asunto(s)
Partículas Elementales , Gases/química , Modelos Teóricos , Análisis Espectral/métodos , Frío , Electrones , Teoría Cuántica , Dispersión de Radiación , Termodinámica
19.
Phys Rev Lett ; 126(1): 019201, 2021 01 08.
Artículo en Inglés | MEDLINE | ID: mdl-33480758
20.
Phys Rev Lett ; 115(15): 152002, 2015 Oct 09.
Artículo en Inglés | MEDLINE | ID: mdl-26550717

RESUMEN

The rare decay B→πℓ^{+}ℓ^{-} arises from b→d flavor-changing neutral currents and could be sensitive to physics beyond the standard model. Here, we present the first ab initio QCD calculation of the B→π tensor form factor f_{T}. Together with the vector and scalar form factors f_{+} and f_{0} from our companion work [J. A. Bailey et al., Phys. Rev. D 92, 014024 (2015)], these parametrize the hadronic contribution to B→π semileptonic decays in any extension of the standard model. We obtain the total branching ratio BR(B^{+}→π^{+}µ^{+}µ^{-})=20.4(2.1)×10^{-9} in the standard model, which is the most precise theoretical determination to date, and agrees with the recent measurement from the LHCb experiment [R. Aaij et al., J. High Energy Phys. 12 (2012) 125].


Asunto(s)
Partículas Elementales , Modelos Teóricos , Física Nuclear , Protones
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