RESUMEN
Diagnostic routine and knowledge about the therapy regimes of infectious diseases like malaria gain in importance due to globalization, global warming, and increasing numbers of refugees. We report a case of a 66-year-old patient who presented with severe abdominal pain, most prominent in the left upper abdomen. He was recently hospitalized with severe falciparum malaria, diagnosed after returning from a trip around the world. Upon readmission, laboratory results showed post-artesunate delayed hemolysis. The ultrasound examination was highly suspicious of splenic rupture, confirmed by the immediately performed CT scan. In this case, the prompt diagnosis allowed the initiation of adequate conservative therapy including intensive care monitoring and hemodynamic stabilization.
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Rotura del Bazo , Humanos , Anciano , Rotura del Bazo/etiología , Rotura del Bazo/diagnóstico por imagen , Rotura del Bazo/terapia , Masculino , Malaria Falciparum/diagnóstico , Malaria Falciparum/complicaciones , Diagnóstico Diferencial , Artesunato/uso terapéutico , Tomografía Computarizada por Rayos X , Ultrasonografía , Viaje , Resultado del Tratamiento , Antimaláricos/uso terapéutico , Rotura EspontáneaRESUMEN
INTRODUCTION: This study aims to assess the safety and clinical efficacy of percutaneous splenic embolization (PSE) and splenectomy as approaches to treating cases of traumatic splenic rupture (TSR). MATERIAL AND METHODS: Eligible articles published throughout August 2023 were identified. Endpoints compared between PSE and splenectomy patient groups included operative time, intraoperative hemorrhage, duration of hospitalization, postoperative complication rates, and measures of immune function. RESULTS: Thirteen studies, involving 474 and 520 patients in the PSE and splenectomy groups respectively, were incorporated into this meta-analysis. As compared to the splenectomy group, individuals treated via PSE exhibited a significant reduction in pooled operative time (p < 0.00001) and hospitalization duration (p < 0.00001), with corresponding reductions in rates of intraoperative hemorrhage (p < 0.00001), total complications (p < 0.0001), incisional infection (p < 0.0001), ileus (p = 0.0004), and abdominal infection (p = 0.02). The immune status of these PSE group patients was also improved, as evidenced by significantly higher pooled CD4+ (30 days), CD4+/CD8+ (30 days), and CD3+ (30 days) values (p < 0.0001, 0.0001, and 0.0001, respectively). CONCLUSIONS: Compared to splenectomy, PSE-based TSR treatment can significantly reduce operative time, rate of postoperative complications, and incidence of intraoperative hemorrhage, while improving post-procedural immune functionality.
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Embolización Terapéutica , Complicaciones Posoperatorias , Esplenectomía , Rotura del Bazo , Humanos , Embolización Terapéutica/métodos , Esplenectomía/métodos , Rotura del Bazo/terapia , Rotura del Bazo/etiología , Complicaciones Posoperatorias/epidemiología , Tempo Operativo , Tiempo de Internación , Resultado del TratamientoRESUMEN
Patients treated with splenic artery embolization (SAE) >48 hours after a blunt injury for a delayed splenic rupture (DSR) were assessed for the need for a subsequent splenectomy. Thirty-four patients underwent SAE for DSR over 10 years at our level 1 trauma center, performed at a median of 4.5 days after the injury (interquartile range = 5.5), and the patients were followed up for a median of 11 months (interquartile range = 31). There were 3 occurrences of rebleeds, and 2 patients required splenectomy (5.9%). This study showed that treatment with SAE after DSR results in splenic salvage in 94.1% of patients.
Asunto(s)
Embolización Terapéutica , Hemorragia/terapia , Arteria Esplénica , Rotura del Bazo/terapia , Heridas no Penetrantes/terapia , Adulto , Embolización Terapéutica/efectos adversos , Femenino , Hemorragia/diagnóstico por imagen , Hemorragia/etiología , Humanos , Masculino , Persona de Mediana Edad , Esplenectomía , Arteria Esplénica/diagnóstico por imagen , Rotura del Bazo/diagnóstico por imagen , Rotura del Bazo/etiología , Factores de Tiempo , Resultado del Tratamiento , Heridas no Penetrantes/diagnóstico por imagen , Heridas no Penetrantes/etiologíaRESUMEN
Dengue infection varies from a mild febrile form to more severe disease with plasma leakage, shock, and multiorgan failure. Several serious complications such as cardiomyopathy, encephalopathy, encephalitis, hepatic damage, and neural manifestations cause organ damage in dengue infection. Splenic rupture, a less well known but life-threatening complication, can occur in dengue. The mechanism of splenic rupture in dengue is still unclear. Optimal therapeutic management is required to save the lives of patients with this complication. The objective of this study was to conduct a systematic review of studies documenting the development of spontaneous nontraumatic splenic rupture in patients with dengue infection. In March 2018, a search was conducted systematically in nine electronic databases, in addition to hand- searching. A total of 127 references were exported to Endnote; 47 references remained after removing duplicates. Finally, 16 reports met the inclusion criteria and represented 17 cases. All articles were evaluated and data extracted according to predefined criteria: number of cases, age, sex, severity of dengue disease, days of illness before admission, methods of definitive diagnosis, timing of the event, and management and outcome. A total of 17 individual patients including 13 males and four females were found. Most of the patients were young adults (ranging from 20 to 52 years) and diagnosed with computed tomography scan and managed with splenectomy. Four cases were fatal. Pathological splenic rupture in dengue is a rare, life-threatening condition where timely management can achieve a favorable outcome.
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Dengue/complicaciones , Manejo de la Enfermedad , Rotura del Bazo/diagnóstico , Rotura del Bazo/terapia , Adulto , Factores de Edad , Femenino , Humanos , Masculino , Persona de Mediana Edad , Esplenectomía , Rotura del Bazo/diagnóstico por imagen , Rotura del Bazo/epidemiología , Análisis de Supervivencia , Tomografía Computarizada por Rayos X , Adulto JovenRESUMEN
BACKGROUND: Nonoperative management (NOM) has become more common in hemodynamically stable patients with high-grade blunt splenic injury. However, there are no widely accepted guidelines for an optimal and safe timeframe for the initiation of venous thromboembolism (VTE) prophylaxis. The purpose of this study was to explore the association between the timing of VTE prophylaxis initiation and NOM failure rate in isolated high-grade blunt splenic injury. METHODS: We utilized the American College of Surgeons Trauma Quality Improvement Program database (2013-2014) to identify adult patients who underwent NOM for isolated high-grade blunt splenic injuries (grades 3-5). The incidence of NOM failure after the initiation of VTE prophylaxis was compared between two groups: VTE prophylaxis <48 h after admission (early prophylaxis group), and ≥48 h (late prophylaxis group). RESULTS: A total of 816 patients met the inclusion criteria. Of those, VTE prophylaxis was not administered in 525 patients (64.3%), whereas VTE prophylaxis was given <48 h and ≥48 h after admission in 144 and 147 patients, respectively. There was no significant difference in the NOM failure rate after the initiation of VTE prophylaxis between the early and late prophylaxis groups (3.5% versus 3.4%, P = 1.00). In the multiple logistic regression analysis, early initiation of VTE prophylaxis was not significantly associated with NOM failure (OR: 1.32, 95% CI 0.35-4.93, P = 0.68). CONCLUSIONS: The results of our study suggest that early initiation of VTE prophylaxis (<48 h) does not increase the risk of NOM failure in patients with isolated high-grade blunt splenic injury.
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Fibrinolíticos/administración & dosificación , Fibrinolíticos/efectos adversos , Rotura del Bazo/terapia , Tromboembolia Venosa/prevención & control , Adulto , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Rotura del Bazo/complicaciones , Adulto JovenRESUMEN
BACKGROUND: The spleen is the second most commonly injured solid organ during blunt abdominal trauma. Although total splenectomy is frequently performed for injury, splenic rupture can also be managed by splenic embolization. For these patients, current Advisory Committee on Immunization Practices (ACIP) recommendations indicate that if 50% or more of the splenic mass is lost, patients should be treated as though they are asplenic. We have previously demonstrated that compliance with ACIP guidelines regarding immunization after splenectomy is poor. Compliance with vaccination in the setting of splenic embolization for trauma is unknown and we hypothesized patients would not receive the recommended immunizations. MATERIALS AND METHODS: All admissions at our level 1 trauma center requiring splenic embolization secondary to traumatic injury between January 1, 2010, and November 1, 2015, were reviewed. Demographic and injury data, dates and imaging of splenic embolizations, immunization documentation, subsequent vaccination boosters received, and outcomes were collected from the medical record. The proportion of spleen embolized was estimated by review of angiographic imaging using an established method. RESULTS: Nine thousand nine hundred sixty-five trauma patients were admitted during the period studied. Nineteen patients met inclusion and exclusion criteria. Median age of the patient population was 35 y, 85% were male, and median injury severity score was 28. Of these, 15 patients underwent a splenic embolization, in which 50% or more of their splenic mass was lost through embolization. Eight patients received at least one immunization before discharge. Six received initial immunizations against Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae, while three received only the initial immunization against S pneumoniae. None of the 15 patients received any ACIP-recommended booster. Of the four patients having less than 50% of their spleen embolized, three wrongly received immunization against encapsulated organisms before hospital discharge. CONCLUSIONS: Trauma patients undergoing splenic embolization at our institution receive postsplenectomy immunizations incorrectly and had no recorded booster vaccines. We speculate that this is common among the U.S. trauma centers. Review of immunization practices in our trauma and nontrauma patient populations is underway in our health system to improve the care of these patients, and our experience may serve as a guide for other centers to reduce complications associated with asplenia.
Asunto(s)
Embolización Terapéutica/efectos adversos , Complicaciones Posoperatorias/prevención & control , Rotura del Bazo/terapia , Centros Traumatológicos/estadística & datos numéricos , Vacunación/estadística & datos numéricos , Traumatismos Abdominales/complicaciones , Adulto , Angiografía , Embolización Terapéutica/normas , Femenino , Adhesión a Directriz/estadística & datos numéricos , Humanos , Huésped Inmunocomprometido , Puntaje de Gravedad del Traumatismo , Masculino , Persona de Mediana Edad , Complicaciones Posoperatorias/inmunología , Complicaciones Posoperatorias/microbiología , Guías de Práctica Clínica como Asunto , Bazo/diagnóstico por imagen , Bazo/inmunología , Bazo/lesiones , Bazo/cirugía , Esplenectomía/efectos adversos , Esplenectomía/normas , Rotura del Bazo/diagnóstico , Rotura del Bazo/diagnóstico por imagen , Rotura del Bazo/etiología , Centros Traumatológicos/normas , Estados Unidos , Vacunación/normas , Heridas no Penetrantes/complicaciones , Adulto JovenRESUMEN
BACKGROUND: We aimed to review liver injury experience in a level 1 trauma center; namely clinical presentation, grading, management approach and clinical outcomes. METHODS: It is a retrospective analysis to include all blunt liver injury patients who were admitted at the Level 1 trauma center over a 3-year period. Data were compared and analyzed based on the liver injury grades and management approaches. RESULTS: Blunt liver injury accounted for 38% of the total blunt abdominal trauma cases with a mean age of 31 ± 13 years. Liver injury grade II (44.7%) was most common followed by grade I (28.8%), grade III (19.1%), grade IV (7.0%) and grade V (0.4%). Blood transfusion was more frequently required in patients with grade IV (p = 0.04). Out of 257 patients with blunt liver trauma, 198 were initially treated conservatively, that was successful in 192 (97%), whereas it failed in 6 (3%) patients due to delayed bleeding from hepatic hematoma, associated splenic rupture and small bowel injury which mandate surgical intervention. Fifty-nine patients (23%) underwent emergent surgery in terms of packing, resection debridement, left lobe hepatectomy and splenectomy. Hepatic complications included biloma, pseudoaneurysm and massive liver necrosis. Subanalysis of data using the World Society of Emergency Surgery (WSES) classification revealed 19 patients were categorized as a WSES grade IV who needed surgical intervention without having an initial computerized tomography scanning. The overall mortality was 7.8% which was comparable among the conservative and operative group. CONCLUSIONS: In our center, low grade liver injury in young males prevails. NOM is successful even for high graded injuries. All conservatively treated patients with high-grade liver injuries should be closely monitored for signs of failure of the non-operative management. Introducing the new WSES classification makes clear how is important the hemodynamic status of the patients despite the lesion. However, further larger prospective and multicenter studies are needed to support our findings.
Asunto(s)
Traumatismos Abdominales/terapia , Hígado/patología , Heridas no Penetrantes/terapia , Traumatismos Abdominales/cirugía , Adolescente , Adulto , Femenino , Hemorragia/etiología , Hepatectomía/métodos , Humanos , Masculino , Estudios Retrospectivos , Esplenectomía/métodos , Rotura del Bazo/terapia , Centros Traumatológicos , Heridas no Penetrantes/cirugía , Adulto JovenRESUMEN
BACKGROUND: Babesiosis is a zoonotic parasitic infection transmitted by the tick, Ixodes scapularis. Splenic infarct and rupture are infrequent complications of Babesia parasitemia, and have not been previously reported in the emergency medicine literature. CASE REPORT: We present two separate cases seen within 1 month at our institution: a case of splenic rupture and another case of splenic infarction due to Babesia parasitemia. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Babesia infection in humans is increasingly prevalent in both the United States and worldwide, and clinical manifestations can range from subclinical to fulminant infections. An unusual but potentially fatal complication of babesiosis is splenic infarctions and rupture. Due to the endemicity of this parasite, a careful history and level of suspicion will enable the emergency physician to consider and test for babesiosis in patients with splenic injuries and without obvious traditional risk factors.
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Babesiosis/complicaciones , Infarto/parasitología , Rotura del Bazo/parasitología , Babesiosis/diagnóstico , Babesiosis/terapia , Terapia Combinada , Diagnóstico Diferencial , Humanos , Infarto/diagnóstico , Infarto/terapia , Masculino , Persona de Mediana Edad , Rotura del Bazo/diagnóstico , Rotura del Bazo/terapiaRESUMEN
Splenic rupture in the neonatal period is a rare condition that can be complicated by hemorrhagic shock. The symptoms are not very specific, rendering the diagnosis difficult and often delayed; sometimes only discovered at autopsy. We report five cases diagnosed in the Rhône-Alpes region of France. From these observations and from a review of the literature, the circumstances of the occurrence, the clinical signs, and the therapeutic possibilities are discussed. In the presence of severe anemia with pallor and abdominal distension, particularly in the context of a difficult birth, an abdominal ultrasound must be urgently performed and surgical management promptly considered. CONCLUSION: This pathology must be known to the neonatologist so that she/he can quickly evoke it, given that it can quickly become life-threatening. What is known: ⢠Splenic rupture in the neonatal period is a rare condition that can be complicated by hemorrhagic shock and quickly lead to the death of the newborn. ⢠The symptoms are not very specific, rendering the diagnosis difficult and often delayed. What is new: ⢠This is the first publication bringing together as many clinical cases on the subject reporting in particular very serious cases to alert the clinician on this pathology and its diagnostic urgency. ⢠We propose a clear therapeutic behavior to help the clinician in his daily practice.
Asunto(s)
Dilatación Gástrica/etiología , Hemoperitoneo/etiología , Hipovolemia/etiología , Choque Hemorrágico/etiología , Rotura del Bazo/complicaciones , Rotura del Bazo/diagnóstico , Anemia/etiología , Resultado Fatal , Femenino , Francia , Hemoperitoneo/diagnóstico por imagen , Humanos , Recién Nacido , Masculino , Mucopolisacaridosis I/complicaciones , Mucopolisacaridosis I/diagnóstico , Esplenectomía , Rotura del Bazo/terapia , UltrasonografíaRESUMEN
INTRODUCTION: Management of splenic rupture in haemodynamically stable children is non-surgical treatment. However, complications can occur during follow-up. Objective: to study the frequency, evolution and treatment of complications of conservative treatment of splenic rupture. Secondary objective: to evaluate the results of the American Pediatric Surgical Association (APSA) clinical guideline in conservative treatment. MATERIAL AND METHODS: Retrospective study of patients with abdominal trauma between 2010-2016. We included children under 15 years of age with splenic injury after blunt abdominal trauma. Demographic variables, mechanism and degree of injury of American Association for the Surgery of Trauma were studied in the sample. The complications, the time of onset and their treatment were analyzed. The treatment was based on the recommendations of the APSA with the exception of ultrasound follow-up. In case of complications and according to the clinical and characteristics, embolization was indicated. RESULTS: Twenty-eight patients were attended, 21 males (75%). The median age was 8.35 years (6.28-11.35). Seven patients (25%) presented complications: two arteriovenous fistula (AVF), three pseudo-aneurysms and two hemorrhages. The median time to diagnosis of complications was 5.67 days (P25 4- P75 5.75). Embolization was performed in two patients with pseudo-aneurysm. Another patient underwent emergency splenectomy for rebleeding. The rest of the complications resolved spontaneously. CONCLUSIONS: In splenic rupture, unlike APSA, ultrasound monitoring is useful to rule out early complications.
INTRODUCCION: El manejo estándar de las lesiones esplénicas en pacientes hemodinámicamente estables es el tratamiento no quirúrgico. Sin embargo, durante el seguimiento pueden surgir complicaciones. Objetivo: estudiar la frecuencia, evolución y tratamiento de las complicaciones del tratamiento conservador del traumatismo esplénico. Objetivo secundario: evaluar los resultados de la guía clínica de la American Pediatric Surgical Association (APSA) en el tratamiento conservador. MATERIAL Y METODOS: Estudio retrospectivo de pacientes con traumatismo abdominal entre 2010-2016. Se incluyeron menores de 15 años con lesión esplénica tras un traumatismo abdominal cerrado. En la muestra se estudiaron variables demográficas, mecanismo y grado de lesión según la American Association for the Surgery of Trauma. Se analizaron las complicaciones, el tiempo de aparición y su tratamiento. El tratamiento se fundamentó en las recomendaciones de la APSA a excepción del seguimiento ecográfico. En caso de aparición de complicaciones y en función de la clínica y de las características se indicó tratamiento con embolización. RESULTADOS: Se atendieron 28 pacientes, 21 varones (75%). La mediana de edad fue 8,35 años (6,28-11,35). Siete pacientes (25%) presentaron complicaciones: dos fístulas arteriovenosas (FAV), tres pseudoaneurismas y dos hemorragias. La media de tiempo para el diagnóstico de las complicaciones fue de 5,67 días. En dos pacientes con pseudoaneurisma se realizó embolización. Un paciente fue sometido a esplenectomía de urgencia por resangrado. El resto de complicaciones se resolvieron espontáneamente. CONCLUSIONES: En el traumatismo esplénico, a diferencia de la APSA, el seguimiento ecográfico en pacientes con lesiones de alto grado es útil para descartar complicaciones de forma precoz.
Asunto(s)
Traumatismos Abdominales/complicaciones , Tratamiento Conservador/métodos , Rotura del Bazo/terapia , Heridas no Penetrantes/complicaciones , Aneurisma Falso/epidemiología , Aneurisma Falso/etiología , Fístula Arteriovenosa/epidemiología , Fístula Arteriovenosa/etiología , Niño , Embolización Terapéutica/métodos , Femenino , Estudios de Seguimiento , Hemorragia/epidemiología , Hemorragia/etiología , Humanos , Masculino , Estudios Retrospectivos , Esplenectomía/métodos , Rotura del Bazo/etiología , Resultado del TratamientoRESUMEN
The authors present the case of a postpartum splenic rupture induced probably by iatrogenic injury (recent vaginal delivery with a prolonged expulsion with uterine fundus compression) including the left hypochondria region costal grid. The case was solved with splenic preservation and achieving hemostasis only by local plugging and Gelaspon. The case raised also other problems regarding the etiology of splenic rupture, in establishing a causal relationship between a intrapartum splenic injury, and the three episodes of inferior genital tract hemorrhaging, in establishing the cause of the infectious syndrome from the 24h postpartum day, (parietal infection or splenic abscess requiring splenectomy).
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Complicaciones del Trabajo de Parto/terapia , Trastornos Puerperales/etiología , Trastornos Puerperales/terapia , Rotura del Bazo/etiología , Rotura del Bazo/terapia , Adulto , Femenino , Humanos , Enfermedad Iatrogénica , Complicaciones del Trabajo de Parto/diagnóstico , Complicaciones del Trabajo de Parto/etiología , Embarazo , Trastornos Puerperales/diagnóstico , Esplenectomía , Rotura del Bazo/diagnósticoAsunto(s)
Síndrome Linfoproliferativo Autoinmune/terapia , Embolización Terapéutica , Bazo/diagnóstico por imagen , Arteria Esplénica/cirugía , Rotura del Bazo/terapia , Adolescente , Síndrome Linfoproliferativo Autoinmune/complicaciones , Síndrome Linfoproliferativo Autoinmune/diagnóstico , Niño , Preescolar , Diagnóstico Diferencial , Femenino , Humanos , Rotura del Bazo/complicaciones , Rotura del Bazo/diagnóstico , Resultado del TratamientoAsunto(s)
Anemia/diagnóstico , Colonoscopía , Hematoma/diagnóstico , Hemoperitoneo/diagnóstico , Rotura del Bazo/diagnóstico , Anciano , Anemia/etiología , Tratamiento Conservador , Femenino , Hematoma/complicaciones , Hematoma/diagnóstico por imagen , Hematoma/terapia , Hemoperitoneo/diagnóstico por imagen , Hemoperitoneo/etiología , Humanos , Enfermedades del Bazo/complicaciones , Enfermedades del Bazo/diagnóstico , Enfermedades del Bazo/diagnóstico por imagen , Enfermedades del Bazo/terapia , Rotura del Bazo/complicaciones , Rotura del Bazo/diagnóstico por imagen , Rotura del Bazo/terapia , Tomografía Computarizada por Rayos XRESUMEN
BACKGROUND/AIMS: We evaluated the effectiveness of various therapies to treat the traumatic splenic rupture by using data from our single center. METHODOLOGY: From July 2008 to Jan 2014, 125 patients who were diagnosis spleen rupture without other organ injury were included into our present study. We divided these patients into two groups according to the managements of the splenic rupture: the operative management (OM) group (48 patients) and the non-operative management (NOM) group (77 patients). We compared the baseline characteristics and long-term outcomes of two groups. the OM group was divided into three sub-groups according to the different operative methods: the total splenectomy group, partial splenectomy group and radiofrequency ablation (RFA) group. RESULTS: Splenic injuries were most commonly observed in abdominal trauma: traffic accidents (49 cases), fall from height (36 cases), strike (22 cases), assaults (11 cases), and sports (7 cases). Of the patients included in our study, 48 patients accepted OM, and 77 patients accepted NOM. The baseline characteristics, including age, gender, BMI, and underlying diseases, were comparable between the two groups. However, the OM group patients exhibited more severe splenic rupture according to the AAST grade (P = 0.000). The three subgroups in the OM group (total splenectomies group (26 cases), partial splenectomy (12 patients), RFA-assisted spleen-preserving surgery (10 patients) exhibited no significant differences with respect to intraoperative data or postoperative recovery. The length of hospital stay in the NOM group was significantly longer than that in the OM group (6.8 ± 1.4 VS 3.4 ± 0.8, P = 0.000), but the OM and NOM patients reported comparable quality of life according to the SF-36 scale. CONCLUSION: In conclusion, the outcomes of operative management for splenic rupture were comparable, and the OM and the NOM patients exhibited a similar quality of life after splenic rupture, although longer hospital stays were observed in the NOM group.
Asunto(s)
Ablación por Catéter , Esplenectomía , Rotura del Bazo/terapia , Adulto , Ablación por Catéter/efectos adversos , China , Femenino , Humanos , Tiempo de Internación , Masculino , Persona de Mediana Edad , Complicaciones Posoperatorias/etiología , Calidad de Vida , Estudios Retrospectivos , Factores de Riesgo , Esplenectomía/efectos adversos , Esplenectomía/métodos , Rotura del Bazo/diagnóstico , Rotura del Bazo/etiología , Rotura del Bazo/cirugía , Factores de Tiempo , Resultado del TratamientoRESUMEN
A systemic lupus erythematosus (SLE) patient in her mid-30s presented with spontaneous splenic haematoma and rupture. She rapidly deteriorated despite packed red cells and fresh frozen plasma transfusions. She underwent emergent ultraselective angioembolisation of the splenic artery and got stabilised. Spontaneous or atraumatic splenic rupture is rare in SLE and splenic artery embolisation may be life-saving.
Asunto(s)
Embolización Terapéutica , Lupus Eritematoso Sistémico , Arteria Esplénica , Rotura del Bazo , Humanos , Lupus Eritematoso Sistémico/complicaciones , Femenino , Embolización Terapéutica/métodos , Rotura del Bazo/etiología , Rotura del Bazo/terapia , Adulto , Rotura Espontánea , Hematoma/etiología , Hematoma/terapiaRESUMEN
We report on a 35-year-old man who presented to the emergency department with acute abdominal pain, postural hypotension, and tachycardia after having been diagnosed with Epstein-Barr virus infection 1 week before. Abdominal ultrasound and computed tomography revealed splenic rupture, and the patient underwent successful proximal angiographic embolization of the splenic artery. The course was complicated by painful splenic necrosis and respiratory insufficiency due to bilateral pleural effusions. Six weeks later, he additionally developed severe sepsis with Propionibacterium granulosum due to an intrasplenic infected hematoma, which required drainage. All complications were treated without surgical splenectomy, and the patient finally made a full recovery.
Asunto(s)
Drenaje , Embolización Terapéutica , Mononucleosis Infecciosa/complicaciones , Sepsis/terapia , Rotura del Bazo/terapia , Infecciones por Actinomycetales/diagnóstico , Infecciones por Actinomycetales/etiología , Infecciones por Actinomycetales/terapia , Adulto , Humanos , Masculino , Propionibacterium/aislamiento & purificación , Sepsis/diagnóstico , Sepsis/etiología , Rotura del Bazo/complicaciones , Rotura del Bazo/diagnósticoRESUMEN
We report the case of a 61-year-old male patient who suffered a spontaneous (atraumatic) splenic rupture (SSR) following splenic infarction treated by heparin anticoagulation. Splenic rupture precipitated by thrombolytic or anticoagulant therapy has been reported and putatively attributed to unrecognized micro-traumatisms i.e. after resuscitation manoeuvres, leading to massive bleeding upon anticoagulation and secondary splenic rupture. Nevertheless, SSR resulting from splenic infarction and anticoagulation has not been described.
Asunto(s)
Hemostasis Quirúrgica/métodos , Heparina de Bajo-Peso-Molecular/efectos adversos , Bazo , Infarto del Bazo/tratamiento farmacológico , Rotura del Bazo , Anticoagulantes/administración & dosificación , Anticoagulantes/efectos adversos , Heparina de Bajo-Peso-Molecular/administración & dosificación , Humanos , Masculino , Persona de Mediana Edad , Rotura Espontánea/inducido químicamente , Rotura Espontánea/diagnóstico , Rotura Espontánea/terapia , Bazo/diagnóstico por imagen , Bazo/cirugía , Infarto del Bazo/diagnóstico , Rotura del Bazo/inducido químicamente , Rotura del Bazo/diagnóstico , Rotura del Bazo/terapia , Tomografía Computarizada por Rayos X , Resultado del TratamientoRESUMEN
Tuberculosis involving the pancreas is rare. We report a patient with pancreatic tuberculosis complicated by haemorrhage from a splenic artery pseudoaneurysm. As far as we are aware, the development of a splenic artery pseudoaneurysm in association with a large caseating mass of tuberculous pancreatic lymph nodes has not been reported previously. We review the literature and discuss the varied presentations of tuberculosis involving the pancreas or the pancreatic bed and its draining lymph nodes.
Asunto(s)
Aneurisma Falso/microbiología , Aneurisma Roto/microbiología , Hemorragia Gastrointestinal/microbiología , Pancreatitis/microbiología , Arteria Esplénica/microbiología , Rotura del Bazo/microbiología , Tuberculosis Gastrointestinal/complicaciones , Adulto , Aneurisma Falso/terapia , Aneurisma Roto/terapia , Hemorragia Gastrointestinal/terapia , Humanos , Masculino , Pancreatitis/terapia , Rotura Espontánea , Rotura del Bazo/terapia , Tuberculosis Gastrointestinal/terapiaRESUMEN
While the management of penetrating as well as blunt splenic injury with hemodynamic instability is straightforward with immediate operative intervention, the management of blunt splenic injury with stable hemodynamic underwent a paradigm shift over the last 3 decades. Nowadays 80 per cent of hemodynamically stable patients with blunt splenic injury can successfully be treated with a non-operative management. Angiographic embolization in selected cases is generally reported to increase the success rates of non-operative management currently approaching 95 per cent.
Asunto(s)
Embolización Terapéutica/métodos , Bazo/lesiones , Esplenectomía/efectos adversos , Esplenectomía/métodos , Rotura del Bazo/diagnóstico , Rotura del Bazo/terapia , HumanosRESUMEN
This is a case report of a previously healthy female patient with complement-mediated thrombotic microangiopathy (TMA) caused by a systemic cytomegalovirus infection that was successfully treated with plasmapheresis, steroids, and parenteral valganciclovir. Complement-mediated TMA is the result of various genetic mutations leading to complement abnormalities with overactivation of alternate complement pathway in response to a triggering infection. She also had splenic rupture without splenomegaly and was managed successfully without splenectomy.