Detalhe da pesquisa
1.
Chemoproteomics Using Nucleotide Acyl Phosphates Reveals an ATP Binding Site at the Dimer Interface of Procaspase-6.
Biochemistry
; 58(52): 5320-5328, 2019 12 31.
Artigo
Inglês
| MEDLINE | ID: mdl-31095371
2.
Chemoproteomic Evaluation of Target Engagement by the Cyclin-Dependent Kinase 4 and 6 Inhibitor Palbociclib Correlates with Cancer Cell Response.
Biochemistry
; 55(38): 5434-41, 2016 09 27.
Artigo
Inglês
| MEDLINE | ID: mdl-27571378
3.
ATP Acyl Phosphate Reactivity Reveals Native Conformations of Hsp90 Paralogs and Inhibitor Target Engagement.
Biochemistry
; 54(19): 3024-36, 2015 May 19.
Artigo
Inglês
| MEDLINE | ID: mdl-25905789
4.
Hit-to-lead optimization and kinase selectivity of imidazo[1,2-a]quinoxalin-4-amine derived JNK1 inhibitors.
Bioorg Med Chem Lett
; 23(18): 5217-22, 2013 Sep 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23916259
5.
6-Position optimization of tricyclic 4-quinolone-based inhibitors of glycogen synthase kinase-3ß: discovery of nitrile derivatives with picomolar potency.
Bioorg Med Chem Lett
; 22(2): 1005-8, 2012 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-22202172
6.
Synthesis and structure-activity relationship of 4-quinolone-3-carboxylic acid based inhibitors of glycogen synthase kinase-3ß.
Bioorg Med Chem Lett
; 21(19): 5948-51, 2011 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-21873061
7.
Direct CDKN2 Modulation of CDK4 Alters Target Engagement of CDK4 Inhibitor Drugs.
Mol Cancer Ther
; 18(4): 771-779, 2019 04.
Artigo
Inglês
| MEDLINE | ID: mdl-30837298
8.
Correction: Identification of a Tumor Specific, Active-Site Mutation in Casein Kinase 1α by Chemical Proteomics.
PLoS One
; 12(2): e0172649, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-28199383
9.
Identification of a Tumor Specific, Active-Site Mutation in Casein Kinase 1α by Chemical Proteomics.
PLoS One
; 11(3): e0152934, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-27031502
10.
Inhibitor focusing: direct selection of drug targets from proteomes using activity-based probes.
Assay Drug Dev Technol
; 1(1 Pt 2): 137-46, 2003 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-15090140
11.
Profiling native kinases by immuno-assisted activity-based profiling.
Curr Protoc Chem Biol
; 5(3): 213-26, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-24391084
12.
In situ kinase profiling reveals functionally relevant properties of native kinases.
Chem Biol
; 18(6): 699-710, 2011 Jun 24.
Artigo
Inglês
| MEDLINE | ID: mdl-21700206
13.
Functional interrogation of the kinome using nucleotide acyl phosphates.
Biochemistry
; 46(2): 350-8, 2007 Jan 16.
Artigo
Inglês
| MEDLINE | ID: mdl-17209545