Detalhe da pesquisa
1.
Probing Liver Injuries Induced by Thioacetamide in Human In Vitro Pooled Hepatocyte Experiments.
Int J Mol Sci
; 25(6)2024 Mar 13.
Artigo
Inglês
| MEDLINE | ID: mdl-38542239
2.
Assessing Kidney Injury Induced by Mercuric Chloride in Guinea Pigs with In Vivo and In Vitro Experiments.
Int J Mol Sci
; 24(8)2023 Apr 18.
Artigo
Inglês
| MEDLINE | ID: mdl-37108594
3.
Genomics and metabolomics of early-stage thioacetamide-induced liver injury: An interspecies study between guinea pig and rat.
Toxicol Appl Pharmacol
; 430: 115713, 2021 11 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34492290
4.
Comparative Proteomic Analysis of Liver Steatosis and Fibrosis after Oral Hepatotoxicant Administration in Sprague-Dawley Rats.
Toxicol Pathol
; 46(2): 202-223, 2018 02.
Artigo
Inglês
| MEDLINE | ID: mdl-29378501
5.
Molecular Structure-Based Large-Scale Prediction of Chemical-Induced Gene Expression Changes.
J Chem Inf Model
; 57(9): 2194-2202, 2017 09 25.
Artigo
Inglês
| MEDLINE | ID: mdl-28796500
6.
Mining kidney toxicogenomic data by using gene co-expression modules.
BMC Genomics
; 17(1): 790, 2016 10 10.
Artigo
Inglês
| MEDLINE | ID: mdl-27724849
7.
Predicting Rat and Human Pregnane X Receptor Activators Using Bayesian Classification Models.
Chem Res Toxicol
; 29(10): 1729-1740, 2016 10 17.
Artigo
Inglês
| MEDLINE | ID: mdl-27603675
8.
Systems toxicology of chemically induced liver and kidney injuries: histopathology-associated gene co-expression modules.
J Appl Toxicol
; 36(9): 1137-49, 2016 09.
Artigo
Inglês
| MEDLINE | ID: mdl-26725466
9.
Binding free energies for nicotine analogs inhibiting cytochrome P450 2A6 by a combined use of molecular dynamics simulations and QM/MM-PBSA calculations.
Bioorg Med Chem
; 22(7): 2149-56, 2014 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24631364
10.
Synthesis and evaluation of Strychnos alkaloids as MDR reversal agents for cancer cell eradication.
Bioorg Med Chem
; 22(3): 1148-55, 2014 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24405813
11.
Exposure to PFAS chemicals induces sex-dependent alterations in key rate-limiting steps of lipid metabolism in liver steatosis.
Front Toxicol
; 6: 1390196, 2024.
Artigo
Inglês
| MEDLINE | ID: mdl-38903859
12.
Using a Graph Convolutional Neural Network Model to Identify Bile Salt Export Pump Inhibitors.
ACS Omega
; 8(24): 21853-21861, 2023 Jun 20.
Artigo
Inglês
| MEDLINE | ID: mdl-37360478
13.
New inhibitor of 3-phosphoinositide dependent protein kinase-1 identified from virtual screening.
Bioorg Med Chem Lett
; 22(4): 1629-32, 2012 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-22266037
14.
QSAR classification model for antibacterial compounds and its use in virtual screening.
J Chem Inf Model
; 52(10): 2559-69, 2012 Oct 22.
Artigo
Inglês
| MEDLINE | ID: mdl-23013546
15.
Exploring polypharmacology using a ROCS-based target fishing approach.
J Chem Inf Model
; 52(2): 492-505, 2012 Feb 27.
Artigo
Inglês
| MEDLINE | ID: mdl-22196353
16.
A toxicogenomic approach to assess kidney injury induced by mercuric chloride in rats.
Toxicology
; 442: 152530, 2020 09.
Artigo
Inglês
| MEDLINE | ID: mdl-32599119
17.
Teaching an Old Dog New Tricks: Strategies That Improve Early Recognition in Similarity-Based Virtual Screening.
Front Chem
; 7: 701, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31709231
18.
Mining Public Toxicogenomic Data Reveals Insights and Challenges in Delineating Liver Steatosis Adverse Outcome Pathways.
Front Genet
; 10: 1007, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31681434
19.
Understanding microscopic binding of human microsomal prostaglandin E synthase-1 with substrates and inhibitors by molecular modeling and dynamics simulation.
J Phys Chem B
; 112(24): 7320-9, 2008 Jun 19.
Artigo
Inglês
| MEDLINE | ID: mdl-18476739
20.
Data-driven prediction of adverse drug reactions induced by drug-drug interactions.
BMC Pharmacol Toxicol
; 18(1): 44, 2017 06 08.
Artigo
Inglês
| MEDLINE | ID: mdl-28595649