Detalhe da pesquisa
1.
Reversible Control of RNA Splicing by Photoswitchable Small Molecules.
J Am Chem Soc
; 145(23): 12783-12792, 2023 06 14.
Artigo
Inglês
| MEDLINE | ID: mdl-37276581
2.
Double-clicking peptides onto phosphorothioate oligonucleotides: combining two proapoptotic agents in one molecule.
Angew Chem Int Ed Engl
; 53(39): 10504-9, 2014 Sep 22.
Artigo
Inglês
| MEDLINE | ID: mdl-25138283
3.
Peptide-mediated inhibition of the transcriptional regulator Elongin BC induces apoptosis in cancer cells.
Cell Chem Biol
; 30(7): 766-779.e11, 2023 07 20.
Artigo
Inglês
| MEDLINE | ID: mdl-37354906
4.
Cell-free biosynthesis combined with deep learning accelerates de novo-development of antimicrobial peptides.
Nat Commun
; 14(1): 7197, 2023 11 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37938588
5.
A Chemical Biology Perspective to Therapeutic Regulation of RNA Splicing in Spinal Muscular Atrophy (SMA).
ACS Chem Biol
; 17(6): 1293-1307, 2022 06 17.
Artigo
Inglês
| MEDLINE | ID: mdl-35639849
6.
Synthesis of the l- and d-SH2 domain of the leukaemia oncogene Bcr-Abl.
RSC Chem Biol
; 3(8): 1008-1012, 2022 Aug 03.
Artigo
Inglês
| MEDLINE | ID: mdl-35975004
7.
Antibody-oligonucleotide conjugate achieves CNS delivery in animal models for spinal muscular atrophy.
JCI Insight
; 7(24)2022 12 22.
Artigo
Inglês
| MEDLINE | ID: mdl-36346674
8.
Bistable Photoswitch Allows in Vivo Control of Hematopoiesis.
ACS Cent Sci
; 8(1): 57-66, 2022 Jan 26.
Artigo
Inglês
| MEDLINE | ID: mdl-35106373
9.
Conformational analysis of bivalent estrogen receptor ligands: from intramolecular to intermolecular binding.
Chembiochem
; 12(17): 2587-98, 2011 Nov 25.
Artigo
Inglês
| MEDLINE | ID: mdl-22025425
10.
Combining multiomics and drug perturbation profiles to identify muscle-specific treatments for spinal muscular atrophy.
JCI Insight
; 6(13)2021 07 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34236053
11.
Evaluation of Cell-Penetrating Peptide Delivery of Antisense Oligonucleotides for Therapeutic Efficacy in Spinal Muscular Atrophy.
Methods Mol Biol
; 2036: 221-236, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31410800
12.
Interventions Targeting Glucocorticoid-Krüppel-like Factor 15-Branched-Chain Amino Acid Signaling Improve Disease Phenotypes in Spinal Muscular Atrophy Mice.
EBioMedicine
; 31: 226-242, 2018 May.
Artigo
Inglês
| MEDLINE | ID: mdl-29735415
13.
Identification of a Peptide for Systemic Brain Delivery of a Morpholino Oligonucleotide in Mouse Models of Spinal Muscular Atrophy.
Nucleic Acid Ther
; 27(3): 130-143, 2017 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-28118087
14.
ClickIn: a flexible protocol for quantifying mitochondrial uptake of nucleobase derivatives.
Interface Focus
; 7(2): 20160117, 2017 Apr 06.
Artigo
Inglês
| MEDLINE | ID: mdl-28382203
15.
DNA-controlled bivalent presentation of ligands for the estrogen receptor.
Angew Chem Int Ed Engl
; 50(37): 8592-6, 2011 Sep 05.
Artigo
Inglês
| MEDLINE | ID: mdl-21793134