Detalhe da pesquisa
1.
Inflammatory mediators, oxidative stress and genetic disturbance in rheumatoid arthritis rats supported by alfalfa seeds metabolomic constituents via blocking interleukin-1receptor.
Chem Biodivers
; 21(2): e202301653, 2024 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-38158718
2.
HPLC and GC-MS-based metabolic profiles and in vivo anticonvulsant, sedative, and antinociceptive potentials of truffles Tirmania nivea and Tirmania pinoyi hydromethanolic extracts in mice.
Biomed Chromatogr
; 36(12): e5481, 2022 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-35971328
3.
Bioactive compounds and therapeutic role of Brassica oleracea L. seeds in rheumatoid arthritis rats via regulating inflammatory signalling pathways and antagonizing interleukin-1 receptor action.
Biomarkers
; 26(8): 788-807, 2021 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-34704882
4.
Discovery of 4-benzyloxy and 4-(2-phenylethoxy) chalcone fibrate hybrids as novel PPARα agonists with anti-hyperlipidemic and antioxidant activities: Design, synthesis and in vitro/in vivo biological evaluation.
Bioorg Chem
; 115: 105170, 2021 10.
Artigo
Inglês
| MEDLINE | ID: mdl-34332233
5.
HPLC-ESI/MS profiling, phytoconstituent isolation and evaluation of renal function, oxidative stress and inflammation in gentamicin-induced nephrotoxicity in rats of Ficus spragueana Mildbr. & Burret.
Biomed Chromatogr
; 35(9): e5135, 2021 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-33818792
6.
Synthesis, molecular modeling studies, and anticonvulsant evaluation of novel 1-((2-hydroxyethyl)(aryl)amino)-N-substituted cycloalkanecarboxamides and their acetate esters.
Arch Pharm (Weinheim)
; 351(12): e1800269, 2018 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-30461033
7.
Assessment of anti-inflammatory, antinociceptive, immunomodulatory, and antioxidant activities of Cajanus cajan L. seeds cultivated in Egypt and its phytochemical composition.
Pharm Biol
; 54(8): 1380-91, 2016 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-26452527
8.
Anticonvulsant profiles of certain new 6-aryl-9-substituted-6,9-diazaspiro-[4.5]decane-8,10-diones and 1-aryl-4-substituted-1,4-diazaspiro[5.5]undecane-3,5-diones.
Int J Mol Sci
; 15(9): 16911-35, 2014 Sep 23.
Artigo
Inglês
| MEDLINE | ID: mdl-25250910
9.
Acute doxorubicin toxicity differentially alters cytochrome P450 expression and arachidonic acid metabolism in rat kidney and liver.
Drug Metab Dispos
; 39(8): 1440-50, 2011 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-21571947
10.
Inhibition of soluble epoxide hydrolase confers cardioprotection and prevents cardiac cytochrome P450 induction by benzo(a)pyrene.
J Cardiovasc Pharmacol
; 57(3): 273-81, 2011 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-21383588
11.
Acute doxorubicin cardiotoxicity alters cardiac cytochrome P450 expression and arachidonic acid metabolism in rats.
Toxicol Appl Pharmacol
; 242(1): 38-46, 2010 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-19796650
12.
Alteration of cardiac cytochrome P450-mediated arachidonic acid metabolism in response to lipopolysaccharide-induced acute systemic inflammation.
Pharmacol Res
; 61(5): 410-8, 2010 May.
Artigo
Inglês
| MEDLINE | ID: mdl-20045729
13.
Modulation of cytochrome P450 gene expression and arachidonic acid metabolism during isoproterenol-induced cardiac hypertrophy in rats.
Drug Metab Dispos
; 36(11): 2277-86, 2008 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-18725507
14.
Constitutive expression and inducibility of CYP1A1 in the H9c2 rat cardiomyoblast cells.
Toxicol In Vitro
; 21(8): 1686-91, 2007 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-17719738
15.
Cytochrome P450 epoxygenase metabolite, 14,15-EET, protects against isoproterenol-induced cellular hypertrophy in H9c2 rat cell line.
Vascul Pharmacol
; 58(5-6): 363-73, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23466634
16.
Determination of the dominant arachidonic acid cytochrome p450 monooxygenases in rat heart, lung, kidney, and liver: protein expression and metabolite kinetics.
AAPS J
; 15(1): 112-22, 2013 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-23139020
17.
3-methylcholanthrene and benzo(a)pyrene modulate cardiac cytochrome P450 gene expression and arachidonic acid metabolism in male Sprague Dawley rats.
Br J Pharmacol
; 158(7): 1808-19, 2009 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-19889059