Detalhe da pesquisa
1.
Targeting Mycobacterium tuberculosis pH-driven adaptation.
Microbiology (Reading)
; 170(5)2024 May.
Artigo
Inglês
| MEDLINE | ID: mdl-38717801
2.
Discovery and characterization of antimycobacterial nitro-containing compounds with distinct mechanisms of action and in vivo efficacy.
Antimicrob Agents Chemother
; 67(9): e0047423, 2023 09 19.
Artigo
Inglês
| MEDLINE | ID: mdl-37610224
3.
Response to Hypoxia and the Ensuing Dysregulation of Inflammation Impacts Mycobacterium tuberculosis Pathogenicity.
Am J Respir Crit Care Med
; 206(1): 94-104, 2022 07 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35412961
4.
ppe51 Variants Enable Growth of Mycobacterium tuberculosis at Acidic pH by Selectively Promoting Glycerol Uptake.
J Bacteriol
; 204(11): e0021222, 2022 Nov 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36226966
5.
WhiB6 regulation of ESX-1 gene expression is controlled by a negative feedback loop in Mycobacterium marinum.
Proc Natl Acad Sci U S A
; 114(50): E10772-E10781, 2017 12 12.
Artigo
Inglês
| MEDLINE | ID: mdl-29180415
6.
Identification of New MmpL3 Inhibitors by Untargeted and Targeted Mutant Screens Defines MmpL3 Domains with Differential Resistance.
Antimicrob Agents Chemother
; 63(10)2019 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31405862
7.
Inhibitors of Mycobacterium tuberculosis DosRST signaling and persistence.
Nat Chem Biol
; 13(2): 218-225, 2017 02.
Artigo
Inglês
| MEDLINE | ID: mdl-27992879
8.
HC2091 Kills Mycobacterium tuberculosis by Targeting the MmpL3 Mycolic Acid Transporter.
Antimicrob Agents Chemother
; 62(7)2018 07.
Artigo
Inglês
| MEDLINE | ID: mdl-29661875
9.
Mycobacterium tuberculosis Reporter Strains as Tools for Drug Discovery and Development.
IUBMB Life
; 70(9): 818-825, 2018 09.
Artigo
Inglês
| MEDLINE | ID: mdl-29707888
10.
A Nonsense Mutation in Mycobacterium marinum That Is Suppressible by a Novel Mechanism.
Infect Immun
; 85(2)2017 02.
Artigo
Inglês
| MEDLINE | ID: mdl-27789543
11.
Novel inhibitors of cholesterol degradation in Mycobacterium tuberculosis reveal how the bacterium's metabolism is constrained by the intracellular environment.
PLoS Pathog
; 11(2): e1004679, 2015 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-25675247
12.
SPARTA: Simple Program for Automated reference-based bacterial RNA-seq Transcriptome Analysis.
BMC Bioinformatics
; 17: 66, 2016 Feb 04.
Artigo
Inglês
| MEDLINE | ID: mdl-26847232
13.
Polysorbates prevent biofilm formation and pathogenesis of Escherichia coli O104:H4.
Biofouling
; 32(9): 1131-1140, 2016 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-27667095
14.
Slow growth of Mycobacterium tuberculosis at acidic pH is regulated by phoPR and host-associated carbon sources.
Mol Microbiol
; 94(1): 56-69, 2014 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-24975990
15.
The Carbonic Anhydrase Inhibitor Ethoxzolamide Inhibits the Mycobacterium tuberculosis PhoPR Regulon and Esx-1 Secretion and Attenuates Virulence.
Antimicrob Agents Chemother
; 59(8): 4436-45, 2015 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-25987613
16.
Mycobacterium tuberculosis responds to chloride and pH as synergistic cues to the immune status of its host cell.
PLoS Pathog
; 9(4): e1003282, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23592993
17.
The Mycobacterium tuberculosis MmpL3 inhibitor MSU-43085 is active in a mouse model of infection.
Microbiol Spectr
; 12(1): e0367723, 2024 Jan 11.
Artigo
Inglês
| MEDLINE | ID: mdl-38078724
18.
A bacterial E3 ubiquitin ligase targets a host protein kinase to disrupt plant immunity.
Nature
; 448(7151): 370-4, 2007 Jul 19.
Artigo
Inglês
| MEDLINE | ID: mdl-17637671
19.
Molecular Mechanisms of MmpL3 Function and Inhibition.
Microb Drug Resist
; 29(5): 190-212, 2023 May.
Artigo
Inglês
| MEDLINE | ID: mdl-36809064
20.
A genetic selection for Mycobacterium smegmatis mutants tolerant to killing by sodium citrate defines a combined role for cation homeostasis and osmotic stress in cell death.
mSphere
; 8(5): e0035823, 2023 10 24.
Artigo
Inglês
| MEDLINE | ID: mdl-37681985