[Erythema elevatum diutinum]. / Erythema elevatum diutinum.

Three cases of Erythema Elevatum Diutinum are reported and a revision of the literature about this subject is made. The authors described extensively the general and cutaneous clinical picture. They precise the histological characteristics and mention other dermatological proceses from which this entity must be differentiated. Finally the ethiology and treatment of this clinical picture are discussed.

[Cutaneous mastocytosis in twins]. / Mastocitosis cutánea en gemelos.

The case of a pair of fraternal twins of seven months of age with cutaneous Mastocyte disease is presented. A brief historical survey of this condition is made. The histological picture is described with special emphasis on the mastocyte and its physiopathology. A description of the clinical aspect of the Pigmentous Urticaria in children and a brief reference to the other clinical forms of Mastocyte disease in its localized and systemic manifestations are presented. The different etio-pathogenic genetic theories related to this disease are considered, on account of the occurrence of this condition in members of a same family and in identical and fraternal twins. A revision of cases available up to date is made. The conclusion is that the etio-pathogenic problem is not solved yet, although the Mastocyte disease is considered as depending on a hereditary factor, not clearly defined yet, predisposing to this condition.

[Epidermotropic reticulosis (Woringer-Kolopp disease)]. / Reticulosis epidermotrópica (enfermedad de Woringer-Kolopp).

The Woringer-Kolopp's disease must be considered a clinical-pathologic variant of mycosis fungoides. It is characterized by heterogenous clinical features and a peculiar histological aspect given by the cellular infiltration of the epidermis. The orgin of the reticular elements is discussed. Though some investigators think they originate in the dermis, others consider their origin to be "in situ". The evolution and prognosis are not well defined, as is the case with the hyperplastic, heteromorphic and polymorphic reticuloses. The case presented has had Hodgkin's disease and then developed a picture of pagetoid reticulosis.

[Nonvenereal lymphangitis of the penis]. / Linfangitis no venérea del pene

Two personal cases of Non venereal Lymphangitis of the Penis are presented in 23 and 28 men, and 38 cases from the literature are reviewed. This benign self-limiting condition is not too well known among dermatologists and urologists. The clinical changes, in particular noted by palpation are characteristic: painless firm cartilaginous cord freely movable behind the corona of glans penis in the coronary sulcus. The inguinal lymph nodes are not involved. The microscopic features in one of our patients demonstrated that the lesion results from cystic dilatation of secondary organization of the thrombus. The etiology is unknown. We favour the mecanical trauma as an important factor based on excessive sexual activity of the patients.

[Inflammatory verrucous epidermal nevus (IVEN)]. / Nevo epidérmico verrugoso inflamatorio (NEVIL)

From the original description of Altman and Mehregan (1971) a new clinical type of linear nevus is known as inflammatory linear verrucous epidermal nevus (ILVEN). Two girls of 5 and 4 years of age are reported. One of them had good therapeutical results with the use of trichloroacetic acid. The clinical and histopathological aspects of this nevus are reviewed and the differential diagnosis should be done with: lichen planus, lichen striatus, linear psoriasis, zoniform dermatitis, naevus unius lateris.

[Melanoma (Hutchinson's lentigo maligna) having spontaneous regression. A case of immunologic importance]. / Melanoma (léntigo maligno de Hutchinson) de regresión espontánea. Caso de interés inmunológico.

I. A brief description is given of the general aspects of skin melanomas, including some personal observations. II. Immunologic facts are mentioned demonstrating: A) The existence of specific circulating antibodies demonstrated by immunofluorescence techniques, by the useful action of blood from patients with duly controlled melanoma injected into other melanoma patients, and by the verification that blood serum from a melanoma patient inhibits cultures thereof. B) As regards cell-mediated immunity, this is normal when a melanoma cure is obtained, and abnormal when no cure takes place. C) There exist melanoma remissions in patients treated with specific or non-specific (BCG) antigens. Spontaneous regression has also been observed in some melanomas. III. A case is presented: a) with spontaneous regression of facial malignant lentigo; b) manifestation of a cervical lymph node metastasis after the primitive tumor had subsided; c) low-degree cell-mediated immunity recuperated spontaneously in an exaggerated manner after radical neck dissection in which none of the lymph nodes proved metastatic; d) manifestation of herpes zoster while the patient presented her best immunologic index; and 2) 11 years' survival since the melanoma made its appearance, and more than 2 years (up to March 1979) since the manifestation of the lymph node metastases.

[Cellulitis. Histopathologic and histochemical study of 100 cases]. / Celulitis. Estudio histopatológico e histoquímico de 100 casos.

An analysis of the bibliographical background is made. A study of 100 cases of cellulitis from the histopathologic and histochemical features is performed. The biopsies were done on patients of the feminine sex as a start of a whole treatment. It is inferred that in cellulitis pathologic, metabolic, hormonal and may be immunological factors, are linked to the malfunction of the vascular changes (micro-pathological angiopathy) in the form of thickening of the walls of capillaries and arterioles, that would generate a muco-edema in the dermo-hypodermic tissues. The cellulitis owing to its typical histological characteristics might be considered as a dystrophic capillary connective mucoidotic edema predominant in the skin of the root of the lower limbs.

[Vegetative dystrophic epidermolysis bullosa. Urogenital manifestations and treatment with hydantoin]. / Epidermólisis ampollar distrófica vegetante. Manifestaciones urogenitales y tratamiento con hidantoína.

Dystrophic epidermolysis bullosa has a rare recessive polydysplastic vegetant variant, which was described by Nicolas et al. Two siblings are reported. The male was affected by urethral lesions, an exceptional finding in this disease. Many members in family died of renal insufficiency . A variety of therapeutics was indicated along ten years. Only hydantoins caused a marked involution of the lesions. An interesting feature was that high drug levels in the blood produced not only common side effects, such as macrulia , but also exacerbation of the dermatosis and growth of new lesions, which took on a botriomicoid aspect.

[Cellulitis. Study of microangiopathy in 254 cases]. / Celulitis. Estudio de la microangiopatía de 254 casos.

In a previous work, Segers and adl., the histological and histochemical study of the features of cellulitis is performed, expliciting the importance in this lipodystrophy of microangiopathy PAS positive. As a complement of that work, we study a group of 254 patients, all females, which came to us to be treated for their cellulitis, general clinical and local laser therapy. All of these patients presenting microangiopathy of their dermohipodermic capillary vessel confirmed by biopsy. These cases were divided in four groups according to the existence or not family antecedents of diabetes mellitus, and positivity or negativity to the test of glucose overcharge, sensibilized with corticoid (Fajans-Conn). The results are extensively described and discussed, and considerations are made referring to the aetiopathogenesis of both entities, diabetes and micro-pathological angiopathy, that could be generically and/or immunologically related.

[Benign circinated pityriasic erythema in children]. / Eritema circinado pitiriásico benigno del niño.

The case is report of a boy aged 6 months whose dermatosis had set in suddenly 15 days before in the form of large round circinate patches on the face, thorax, abdomen, dorsum and extremities. These patches were limited by a slightly elevated erythematous border, the inside of which was constituted by collarette-like epidermal desquamations with central parakerotosis. The patches impairment was observed in the child's general condition. A histopathological study was carried out.

[Eosinophilic migratory nodular panniculitis (human gnathostomiasis)]. / Paniculitis nodular migratoria eosinofílica (gnathostomiasis humana).

The case of a patient with thoracic abdominal and left arm, migratory erythema-edematous plates over a space of three years is described. The histopathologic features reveal a eosinophilic panniculitis due to probable larva migrans (gnathostomiasis). This appears to be the first report on the subject because we have not found any reference to the subject in Argentina bibliographic search.

[Florid papillomatosis of the oral mucosa with bone invasiveness. Anatomo-clinical review of 66 cases of oral florid papillomatosis studied in 20 years]. / Papilomatosis florida de la mucosa bucal con invasión ósea. Revisión Anátomo-clínica de 66 casos de papilomatosis florida bucal estudiados durante veinte años.

Sixty-six cases of P.F. of the mouth cavity have been studied. Osseous maxillary invasion (attack) has been detected (discovered) in five patients. It could be determined that in the first three patients the P.F. was originated in the maxillary sinus but in its development it destroyed bone walls and emerged in the mouth cavity. Moreover, in one of the patients it drilled the mucous of the surco naso-geniano outwards. In the other two cases left something attracted our attention the osseous destruction a invasive squamous x rayed was more important than the damage of the mucous membranes. In the last case a change of P.F. into a carcinoma epidermoide infiltrante was produced after cytostatic treatment; this was already published by us. The percentage of the bone invasion of the oral squamous all carcinoma is similar to the Papillomatosis Florida.

[Arnozán-Dubreuilh depilating folliculitis]. / Foliculitis depilante de Arnozán y Dubreuilh.

Male patient, aged twenty-six years. Having an eight-and-a-half-year- old dermatosis of localized evolution on scalp, under arms, thighs, pubis and legs, characterized by inflammatory papules and follicular and extra-adnexial pustules, tiny scars and lack of hair in the affected areas. The authors present a representative case of "depilating folliculitis" of (Arnozán and Dubreuilh) stressing the following: Uncommon frequency in our country but frequent in warmer climates where it is observed mainly among peasants and sugar-cane workers. Wide-depilated areas principally in folds. Seasonal outbreak. Good response to treatment. A revision of the theme is made emphasizing the histopathologic pathogenesis.

[Cellulite]. / Celulitis.

In a group of 130 patients carriers of cellulite, that were subjected to a general clinic treatment and local treatment of laser-therapy, the authors, previous to the therapeutics, made an anatomopathologic study of the skin and the adipose tissue. The biopsies were done on patients of the feminine sex, confirming that all these cases presented the histopathologic and histochemical features of cellulite in their dermo-hypodermic tissue. A full study of intolerance to carbohydrates; lipidic, proteic and hormonal metabolism was also performed in all patients. Comparing the different parameters, the authors emphasize the multiple pathogenic varieties of the illness, and the possibility of future risk of macroangiopathy and coronariopathy.

[Scleroatrophying and degenerative keratodermic genodermatosis of the extremities]. / Genodermatosis escleroatrofiante y queratodérmica de las extremidades frequentemente degenerativa.

A case of a picture described by Huriez et al. under the title of scleatrophying and keratodermic genodermatosis of the limbs usually degenerative is presented. In the genealogic study it was observed that seven out of the sixteen members that belonged to this primary family group were affected or probably affected and it is stressed that one of them died from metastasis of spinocellular epithelioma.

[Keratodermic genodermatosis with hydrocystomas, miliary cysts, xanthelasmas, nail and dental dystrophies, and basal cell epitheliomas]. / Genodermatosis queratodérmica con hidrocistomas, quistes de milium, xantelasmas, distrofias dentarias y ungulares y epiteliomas basocelulares.

Two cases of a condition including palms and soles keratoderma, ectodermal dysplasias and basal cell epitheliomas are reported by the authors, with clinical, genetical and pathological data. The condition is called Keratodermal Genodermatose with hydrocystomas, milium cysts, xanthelasma, dental and nail dysplasias and basal cell epitheliomata (Borda's syndrome).

[Sturge-Weber-Dimitri syndrome associated with Klippel-Trenaunay syndrome]. / Síndrome de Sturge-Weber-Dimitri asociado al síndrome de Klippel-Trenaunay.

A 15 year old boy with congenital angiomatosis showing associated features of Sturge-Weber-Dimitri and Klippel-Trenaunay syndromes is presented by the authors. Some peculiar characteristics are commented in the article.