Detalhe da pesquisa
1.
From modulation of cellular plasticity to potentiation of therapeutic resistance: new and emerging roles of MYB transcription factors in human malignancies.
Cancer Metastasis Rev
; 43(1): 409-421, 2024 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-37950087
2.
Biphasic transcriptional and posttranscriptional regulation of MYB by androgen signaling mediates its growth control in prostate cancer.
J Biol Chem
; 299(1): 102725, 2023 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36410437
3.
Ubiquitination of GRK2 Is Required for the ß-Arrestin-Biased Signaling Pathway of Dopamine D2 Receptors to Activate ERK Kinases.
Int J Mol Sci
; 24(12)2023 Jun 12.
Artigo
Inglês
| MEDLINE | ID: mdl-37373182
4.
Nicotine causes alternative polarization of macrophages via Src-mediated STAT3 activation: Potential pathobiological implications.
J Cell Physiol
; 237(2): 1486-1497, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34647621
5.
Roles of the Functional Interaction between Brain Cholinergic and Dopaminergic Systems in the Pathogenesis and Treatment of Schizophrenia and Parkinson's Disease.
Int J Mol Sci
; 22(9)2021 Apr 21.
Artigo
Inglês
| MEDLINE | ID: mdl-33919025
6.
A novel molecular mechanism responsible for phosphorylation-independent desensitization of G protein-coupled receptors exemplified by the dopamine D3 receptor.
Biochem Biophys Res Commun
; 528(3): 432-439, 2020 07 30.
Artigo
Inglês
| MEDLINE | ID: mdl-32505358
7.
α4ß2 nicotinic acetylcholine receptor downregulates D3 dopamine receptor expression through protein kinase C activation.
Biochem Biophys Res Commun
; 514(3): 665-671, 2019 06 30.
Artigo
Inglês
| MEDLINE | ID: mdl-31078264
8.
Design, synthesis, and systematic evaluation of 4-arylpiperazine- and 4-benzylpiperidine napthyl ethers as inhibitors of monoamine neurotransmitters reuptake.
Bioorg Med Chem
; 26(20): 5538-5546, 2018 11 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30293797
9.
Design, synthesis and in vitro activity of 1,4-disubstituted piperazines and piperidines as triple reuptake inhibitors.
Bioorg Med Chem
; 25(7): 2266-2276, 2017 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28274674
10.
Triple reuptake inhibitors: Design, synthesis and structure-activity relationship of benzylpiperidine-tetrazoles.
Bioorg Med Chem
; 25(20): 5278-5289, 2017 10 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28807575
11.
Design, synthesis, and biological evaluation of arylpiperazine-benzylpiperidines with dual serotonin and norepinephrine reuptake inhibitory activities.
Bioorg Med Chem
; 24(9): 2137-45, 2016 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27041397
12.
Exploration of substituted arylpiperazine-tetrazoles as promising dual norepinephrine and dopamine reuptake inhibitors.
Bioorg Med Chem
; 24(21): 5546-5555, 2016 11 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27647372
13.
Design, synthesis and evaluation of bitopic arylpiperazinephenyl-1,2,4-oxadiazoles as preferential dopamine D3 receptor ligands.
Bioorg Med Chem
; 24(2): 191-200, 2016 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26707842
14.
MYB exhibits racially disparate expression, clinicopathologic association, and predictive potential for biochemical recurrence in prostate cancer.
iScience
; 26(12): 108487, 2023 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38089573
15.
Comparative study of the molecular mechanisms underlying the G protein and ß-arrestin-dependent pathways that lead to ERKs activation upon stimulation by dopamine D2 receptor.
FEBS J
; 290(21): 5204-5233, 2023 11.
Artigo
Inglês
| MEDLINE | ID: mdl-37531324
16.
Anisotropy of Additively Manufactured Co-28Cr-6Mo Influences Mechanical Properties and Biomedical Performance.
ACS Appl Mater Interfaces
; 14(19): 21906-21915, 2022 May 18.
Artigo
Inglês
| MEDLINE | ID: mdl-35532349
17.
ß-Arrestin1 and GPCR kinase2 play permissive roles in Src-mediated endocytosis of α4ß2 nicotinic ACh receptors.
Br J Pharmacol
; 178(17): 3498-3516, 2021 09.
Artigo
Inglês
| MEDLINE | ID: mdl-33844281
18.
Review of recent developments in surface nanocrystallization of metallic biomaterials.
Nanoscale
; 13(4): 2286-2301, 2021 Feb 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33481967
19.
Zinc and cerium synergistically enhance the mechanical properties, corrosion resistance, and osteogenic activity of magnesium as resorbable biomaterials.
Biomed Mater
; 16(4)2021 06 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34030150
20.
Structural Requirements for Modulating 4-Benzylpiperidine Carboxamides from Serotonin/Norepinephrine Reuptake Inhibitors to Triple Reuptake Inhibitors.
Biomol Ther (Seoul)
; 29(4): 392-398, 2021 Jul 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34053940