Detalhe da pesquisa
1.
Preventing occludin tight-junction disruption via inhibition of microRNA-193b-5p attenuates viral load and influenza-induced lung injury.
Mol Ther
; 31(9): 2681-2701, 2023 09 06.
Artigo
Inglês
| MEDLINE | ID: mdl-37340634
2.
Empagliflozin Disrupts a Tnfrsf12a-Mediated Feed Forward Loop That Promotes Left Ventricular Hypertrophy.
Cardiovasc Drugs Ther
; 36(4): 619-632, 2022 08.
Artigo
Inglês
| MEDLINE | ID: mdl-33886003
3.
The Dipeptidyl Peptidase-4 Inhibitor Linagliptin Directly Enhances the Contractile Recovery of Mouse Hearts at a Concentration Equivalent to that Achieved with Standard Dosing in Humans.
Int J Mol Sci
; 21(16)2020 Aug 11.
Artigo
Inglês
| MEDLINE | ID: mdl-32796688
4.
Dysregulated expression but redundant function of the long non-coding RNA HOTAIR in diabetic kidney disease.
Diabetologia
; 62(11): 2129-2142, 2019 11.
Artigo
Inglês
| MEDLINE | ID: mdl-31399844
5.
Dapagliflozin in focal segmental glomerulosclerosis: a combined human-rodent pilot study.
Am J Physiol Renal Physiol
; 314(3): F412-F422, 2018 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29141939
6.
Janus Kinase 2 Regulates Transcription Factor EB Expression and Autophagy Completion in Glomerular Podocytes.
J Am Soc Nephrol
; 28(9): 2641-2653, 2017 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-28424277
7.
Mechanisms of Chronic Muscle Wasting and Dysfunction after an Intensive Care Unit Stay. A Pilot Study.
Am J Respir Crit Care Med
; 194(7): 821-830, 2016 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27058306
8.
The Histone Methyltransferase Enzyme Enhancer of Zeste Homolog 2 Protects against Podocyte Oxidative Stress and Renal Injury in Diabetes.
J Am Soc Nephrol
; 27(7): 2021-34, 2016 07.
Artigo
Inglês
| MEDLINE | ID: mdl-26534922
9.
SIRT1 activation ameliorates hyperglycaemia by inducing a torpor-like state in an obese mouse model of type 2 diabetes.
Diabetologia
; 58(4): 819-27, 2015 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-25563725
10.
Heparan sulfate side chains have a critical role in the inhibitory effects of perlecan on vascular smooth muscle cell response to arterial injury.
Am J Physiol Heart Circ Physiol
; 307(3): H337-45, 2014 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24858854
11.
High glucose induces Smad activation via the transcriptional coregulator p300 and contributes to cardiac fibrosis and hypertrophy.
Cardiovasc Diabetol
; 13: 89, 2014 May 05.
Artigo
Inglês
| MEDLINE | ID: mdl-24886336
12.
Early outgrowth cells release soluble endocrine antifibrotic factors that reduce progressive organ fibrosis.
Stem Cells
; 31(11): 2408-19, 2013 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-23922321
13.
Dipeptidyl peptidase-4 inhibition improves left ventricular function in chronic kidney disease.
Clin Invest Med
; 37(3): E172, 2014 Jun 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24895991
14.
eNOS deficiency predisposes podocytes to injury in diabetes.
J Am Soc Nephrol
; 23(11): 1810-23, 2012 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-22997257
15.
Single cell G-protein coupled receptor profiling of activated kidney fibroblasts expressing transcription factor 21.
Br J Pharmacol
; 180(22): 2898-2915, 2023 11.
Artigo
Inglês
| MEDLINE | ID: mdl-37115600
16.
Altered expression, but small contribution, of the histone demethylase KDM6A in obstructive uropathy in mice.
Dis Model Mech
; 16(9)2023 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37655466
17.
Pressure overload induces ISG15 to facilitate adverse ventricular remodeling and promote heart failure.
J Clin Invest
; 133(9)2023 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37115698
18.
Long-term administration of the histone deacetylase inhibitor vorinostat attenuates renal injury in experimental diabetes through an endothelial nitric oxide synthase-dependent mechanism.
Am J Pathol
; 178(5): 2205-14, 2011 May.
Artigo
Inglês
| MEDLINE | ID: mdl-21514434
19.
Histone deacetylase inhibition attenuates diabetes-associated kidney growth: potential role for epigenetic modification of the epidermal growth factor receptor.
Kidney Int
; 79(12): 1312-21, 2011 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-21389970
20.
Lung and Kidney ACE2 and TMPRSS2 in Renin-Angiotensin System Blocker-Treated Comorbid Diabetic Mice Mimicking Host Factors That Have Been Linked to Severe COVID-19.
Diabetes
; 70(3): 759-771, 2021 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33310740