Detalhe da pesquisa
1.
The coronavirus proofreading exoribonuclease mediates extensive viral recombination.
PLoS Pathog
; 17(1): e1009226, 2021 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33465137
2.
Fitness Barriers Limit Reversion of a Proofreading-Deficient Coronavirus.
J Virol
; 93(20)2019 10 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31341046
3.
Small-Molecule Antiviral ß-d-N4-Hydroxycytidine Inhibits a Proofreading-Intact Coronavirus with a High Genetic Barrier to Resistance.
J Virol
; 93(24)2019 12 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31578288
4.
A mutation in the coronavirus nsp13-helicase impairs enzymatic activity and confers partial remdesivir resistance.
mBio
; 14(4): e0106023, 2023 08 31.
Artigo
Inglês
| MEDLINE | ID: mdl-37338298
5.
Intramuscular vs Intravenous SARS-CoV-2 Neutralizing Antibody Sotrovimab for Treatment of COVID-19 (COMET-TAIL): A Randomized Noninferiority Clinical Trial.
Open Forum Infect Dis
; 10(8): ofad354, 2023 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-37577112
6.
Remdesivir potently inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice.
bioRxiv
; 2020 Apr 27.
Artigo
Inglês
| MEDLINE | ID: mdl-32511392
7.
Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice.
Cell Rep
; 32(3): 107940, 2020 07 21.
Artigo
Inglês
| MEDLINE | ID: mdl-32668216
8.
An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice.
Sci Transl Med
; 12(541)2020 04 29.
Artigo
Inglês
| MEDLINE | ID: mdl-32253226
9.
Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease.
mBio
; 9(2)2018 03 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29511076