Detalhe da pesquisa
1.
Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps.
Cell
; 184(26): 6262-6280.e26, 2021 12 22.
Artigo
Inglês
| MEDLINE | ID: mdl-34910928
2.
Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer.
Cell
; 184(25): 6119-6137.e26, 2021 12 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34890551
3.
The Human and Mouse Enteric Nervous System at Single-Cell Resolution.
Cell
; 182(6): 1606-1622.e23, 2020 09 17.
Artigo
Inglês
| MEDLINE | ID: mdl-32888429
4.
Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy.
Nature
; 629(8013): 919-926, 2024 May.
Artigo
Inglês
| MEDLINE | ID: mdl-38589574
5.
Molecular basis for substrate recruitment to the PRMT5 methylosome.
Mol Cell
; 81(17): 3481-3495.e7, 2021 09 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34358446
6.
Structure-function analysis of the SHOC2-MRAS-PP1C holophosphatase complex.
Nature
; 609(7926): 408-415, 2022 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35831509
7.
Biomarker-Guided Development of DNA Repair Inhibitors.
Mol Cell
; 78(6): 1070-1085, 2020 06 18.
Artigo
Inglês
| MEDLINE | ID: mdl-32459988
8.
Protein biomarkers and alternatively methylated cell-free DNA detect early stage pancreatic cancer.
Gut
; 73(4): 639-648, 2024 Mar 07.
Artigo
Inglês
| MEDLINE | ID: mdl-38123998
9.
Acquired Resistance to KRASG12C Inhibition in Cancer.
N Engl J Med
; 384(25): 2382-2393, 2021 06 24.
Artigo
Inglês
| MEDLINE | ID: mdl-34161704
10.
Transforming Growth Factor-ß Blockade in Pancreatic Cancer Enhances Sensitivity to Combination Chemotherapy.
Gastroenterology
; 165(4): 874-890.e10, 2023 10.
Artigo
Inglês
| MEDLINE | ID: mdl-37263309
11.
Phase Ib and Expansion Study of Gemcitabine, Nab-Paclitaxel, and Ficlatuzumab in Patients With Metastatic Pancreatic Cancer.
Oncologist
; 28(5): 425-432, 2023 05 08.
Artigo
Inglês
| MEDLINE | ID: mdl-36807743
12.
Development and Characterization of Selective FAK Inhibitors and PROTACs with In Vivo Activity.
Chembiochem
; 24(19): e202300141, 2023 10 04.
Artigo
Inglês
| MEDLINE | ID: mdl-37088717
13.
Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway.
Nature
; 547(7664): 453-457, 2017 07 27.
Artigo
Inglês
| MEDLINE | ID: mdl-28678785
14.
Therapeutic avenues for cancer neuroscience: translational frontiers and clinical opportunities.
Lancet Oncol
; 23(2): e62-e74, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-35114133
15.
Discovery of a selective inhibitor of doublecortin like kinase 1.
Nat Chem Biol
; 16(6): 635-643, 2020 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32251410
16.
PIK3CA mutant tumors depend on oxoglutarate dehydrogenase.
Proc Natl Acad Sci U S A
; 114(17): E3434-E3443, 2017 04 25.
Artigo
Inglês
| MEDLINE | ID: mdl-28396387
17.
Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients with resected pancreatic cancer.
Genet Med
; 21(1): 213-223, 2019 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29961768
18.
Refining Classification of Pancreatic Cancer Subtypes to Improve Clinical Care.
Gastroenterology
; 155(6): 1689-1691, 2018 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30419209
19.
Multidisciplinary Standards and Evolving Therapies for Patients With Pancreatic Cancer.
Am Soc Clin Oncol Educ Book
; 44(3): e438598, 2024 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-38781541
20.
Sotorasib Is a Pan-RASG12C Inhibitor Capable of Driving Clinical Response in NRASG12C Cancers.
Cancer Discov
; 14(5): 727-736, 2024 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38236605