Detalhe da pesquisa
1.
Efficacy and safety of zibotentan and dapagliflozin in patients with chronic kidney disease: study design and baseline characteristics of the ZENITH-CKD trial.
Nephrol Dial Transplant
; 39(3): 414-425, 2024 Feb 28.
Artigo
Inglês
| MEDLINE | ID: mdl-37632201
2.
The sodium glucose co-transporter 2 inhibitor dapagliflozin ameliorates the fluid-retaining effect of the endothelin A receptor antagonist zibotentan.
Nephrol Dial Transplant
; 38(10): 2289-2297, 2023 09 29.
Artigo
Inglês
| MEDLINE | ID: mdl-37102226
3.
Physiologically based pharmacokinetics modeling and transporter proteomics to predict systemic and local liver and muscle disposition of statins.
CPT Pharmacometrics Syst Pharmacol
; 13(6): 1029-1043, 2024 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-38576225
4.
Feedback modeling of non-esterified fatty acids in obese Zucker rats after nicotinic acid infusions.
J Pharmacokinet Pharmacodyn
; 40(6): 623-38, 2013 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-24114415
5.
Challenges of a mechanistic feedback model describing nicotinic acid-induced changes in non-esterified fatty acids in rats.
J Pharmacokinet Pharmacodyn
; 40(4): 497-512, 2013 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-23824920
6.
Understanding Statin-Roxadustat Drug-Drug-Disease Interaction Using Physiologically-Based Pharmacokinetic Modeling.
Clin Pharmacol Ther
; 114(4): 825-835, 2023 10.
Artigo
Inglês
| MEDLINE | ID: mdl-37376792
7.
Does the choice of applied physiologically-based pharmacokinetics platform matter? A case study on simvastatin disposition and drug-drug interaction.
CPT Pharmacometrics Syst Pharmacol
; 11(9): 1194-1209, 2022 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35722750
8.
Feedback modeling of non-esterified fatty acids in rats after nicotinic acid infusions.
J Pharmacokinet Pharmacodyn
; 38(1): 1-24, 2011 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-21046209
9.
ADME: Assessing Pharmacokinetic-Pharmacodynamic Parameters of Oligonucleotides.
Methods Mol Biol
; 2036: 317-339, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31410806
10.
Erratum: Publisher Correction: Mathematical model of hemodynamic mechanisms and consequences of glomerular hypertension in diabetic mice.
NPJ Syst Biol Appl
; 5: 9, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-30854224
11.
Mathematical model of hemodynamic mechanisms and consequences of glomerular hypertension in diabetic mice.
NPJ Syst Biol Appl
; 5: 2, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-30564457
12.
Antisense oligonucleotide treatment ameliorates IFN-γ-induced proteinuria in APOL1-transgenic mice.
JCI Insight
; 4(12)2019 06 20.
Artigo
Inglês
| MEDLINE | ID: mdl-31217349
13.
Overexpressing cell systems are a competitive option to primary adipocytes when predicting in vivo potency of dual GPR81/GPR109A agonists.
Eur J Pharm Sci
; 114: 155-165, 2018 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29180298
14.
Mixed Effects Modeling Using Stochastic Differential Equations: Illustrated by Pharmacokinetic Data of Nicotinic Acid in Obese Zucker Rats.
AAPS J
; 17(3): 586-96, 2015 May.
Artigo
Inglês
| MEDLINE | ID: mdl-25693487
15.
Joint feedback analysis modeling of nonesterified fatty acids in obese Zucker rats and normal Sprague-Dawley rats after different routes of administration of nicotinic acid.
J Pharm Sci
; 103(8): 2571-84, 2014 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-24986056
16.
Quantitative analysis of rate and extent of tolerance of biomarkers: application to nicotinic acid-induced changes in non-esterified fatty acids in rats.
Eur J Pharm Sci
; 44(3): 250-64, 2011 Oct 09.
Artigo
Inglês
| MEDLINE | ID: mdl-21856416