Pesquisa | Secretaria de Estado da Saúde

1.

The C-terminal domains of ADAMTS1 contain exosites involved in its proteoglycanase activity.

Minns, Alexander Frederick; Qi, Yawei; Yamamoto, Kazuhiro; Lee, Karen; Ahnström, Josefin; Santamaria, Salvatore.

J Biol Chem ; 299(4): 103048, 2023 04.

Artigo Inglês | MEDLINE | ID: mdl-36813235

2.

Kallikrein directly interacts with and activates Factor IX, resulting in thrombin generation and fibrin formation independent of Factor XI.

Kearney, Katherine J; Butler, Juliet; Posada, Olga M; Wilson, Clare; Heal, Samantha; Ali, Majid; Hardy, Lewis; Ahnström, Josefin; Gailani, David; Foster, Richard; Hethershaw, Emma; Longstaff, Colin; Philippou, Helen.

Proc Natl Acad Sci U S A ; 118(3)2021 01 19.

Artigo Inglês | MEDLINE | ID: mdl-33397811

3.

Post-translational regulation and proteolytic activity of the metalloproteinase ADAMTS8.

Santamaria, Salvatore; Martin, Daniel R; Dong, Xiangyi; Yamamoto, Kazuhiro; Apte, Suneel S; Ahnström, Josefin.

J Biol Chem ; 297(5): 101323, 2021 11.

Artigo Inglês | MEDLINE | ID: mdl-34687701

4.

Factor V has an anticoagulant cofactor activity that targets the early phase of coagulation.

Santamaria, Salvatore; Reglinska-Matveyev, Natalia; Gierula, Magdalena; Camire, Rodney M; Crawley, James T B; Lane, David A; Ahnström, Josefin.

J Biol Chem ; 292(22): 9335-9344, 2017 06 02.

Artigo Inglês | MEDLINE | ID: mdl-28420729

5.

FV/FVa revealed.

Ahnström, Josefin.

Blood ; 137(22): 3011-3013, 2021 06 03.

Artigo Inglês | MEDLINE | ID: mdl-34081120

6.

Mycolactone-Dependent Depletion of Endothelial Cell Thrombomodulin Is Strongly Associated with Fibrin Deposition in Buruli Ulcer Lesions.

Ogbechi, Joy; Ruf, Marie-Thérèse; Hall, Belinda S; Bodman-Smith, Katherine; Vogel, Moritz; Wu, Hua-Lin; Stainer, Alexander; Esmon, Charles T; Ahnström, Josefin; Pluschke, Gerd; Simmonds, Rachel E.

PLoS Pathog ; 11(7): e1005011, 2015 Jul.

Artigo Inglês | MEDLINE | ID: mdl-26181660

7.

Vessel wall BAMBI contributes to hemostasis and thrombus stability.

Salles-Crawley, Isabelle I; Monkman, James H; Ahnström, Josefin; Lane, David A; Crawley, James T B.

Blood ; 123(18): 2873-81, 2014 May 01.

Artigo Inglês | MEDLINE | ID: mdl-24627527

8.

TFPI cofactor function of protein S: essential role of the protein S SHBG-like domain.

Reglinska-Matveyev, Natalia; Andersson, Helena M; Rezende, Suely M; Dahlbäck, Björn; Crawley, James T B; Lane, David A; Ahnström, Josefin.

Blood ; 123(25): 3979-87, 2014 Jun 19.

Artigo Inglês | MEDLINE | ID: mdl-24740810

9.

Identification of functionally important residues in TFPI Kunitz domain 3 required for the enhancement of its activity by protein S.

Ahnström, Josefin; Andersson, Helena M; Hockey, Verity; Meng, Yiran; McKinnon, Thomas A J; Hamuro, Tsutomu; Crawley, James T B; Lane, David A.

Blood ; 120(25): 5059-62, 2012 Dec 13.

Artigo Inglês | MEDLINE | ID: mdl-23074276

10.

Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M.

Christoffersen, Christina; Obinata, Hideru; Kumaraswamy, Sunil B; Galvani, Sylvain; Ahnström, Josefin; Sevvana, Madhumati; Egerer-Sieber, Claudia; Muller, Yves A; Hla, Timothy; Nielsen, Lars B; Dahlbäck, Björn.

Proc Natl Acad Sci U S A ; 108(23): 9613-8, 2011 Jun 07.

Artigo Inglês | MEDLINE | ID: mdl-21606363

11.

Biphasic activation of complement and fibrinolysis during the human nasal allergic response.

Thwaites, Ryan S; Gunawardana, Natasha C; Broich, Verena; Mann, Elizabeth H; Ahnström, Josefin; Campbell, Gaynor A; Lindsley, Sarah; Singh, Nehmat; Tunstall, Tanushree; Lane, David A; Openshaw, Peter J; Hawrylowicz, Catherine M; Hansel, Trevor T.

J Allergy Clin Immunol ; 141(5): 1892-1895.e6, 2018 05.

Artigo Inglês | MEDLINE | ID: mdl-29427640

12.

TFPIα anticoagulant function is highly dependent on protein S in vivo.

Petri, Anastasis; Sasikumar, Parvathy; Folgado, Patricia Badia; Jones, David; Xu, Yaoxian; Ahnström, Josefin; Salles-Crawley, Isabelle I; Crawley, James T B.

Sci Adv ; 10(5): eadk5836, 2024 Feb 02.

Artigo Inglês | MEDLINE | ID: mdl-38306422

13.

Safe and Efficacious Near Superhydrophobic Hemostat for Reduced Blood Loss and Easy Detachment in Traumatic Wounds.

Dong, Yibing; Xu, Yaoxian; Lian, Chengxing; Prak, Krisna; Leo, Hwa Liang; Tetley, Teresa D; Braga, Vania; Emerson, Mike; Ahnström, Josefin; Yap, Choon Hwai.

ACS Appl Mater Interfaces ; 16(4): 4307-4320, 2024 Jan 31.

Artigo Inglês | MEDLINE | ID: mdl-38240181

14.

Activated protein C cofactor function of protein S: a novel role for a Î³-carboxyglutamic acid residue.

Ahnström, Josefin; Andersson, Helena M; Canis, Kevin; Norstrøm, Eva; Yu, Yao; Dahlbäck, Björn; Panico, Maria; Morris, Howard R; Crawley, James T B; Lane, David A.

Blood ; 117(24): 6685-93, 2011 Jun 16.

Artigo Inglês | MEDLINE | ID: mdl-21508412

15.

The TFPIα C-terminal tail is essential for TFPIα-FV-short-protein S complex formation and synergistic enhancement of TFPIα.

Gierula, Magdalena; Noakes, Victoria M; Salles-Crawley, Isabelle I; Crawley, James T B; Ahnström, Josefin.

J Thromb Haemost ; 21(12): 3568-3580, 2023 12.

Artigo Inglês | MEDLINE | ID: mdl-37739040

16.

The first laminin G-like domain of protein S is essential for binding and activation of Tyro3 receptor and intracellular signalling.

Al Kafri, Nour; Ahnström, Josefin; Teraz-Orosz, Adrienn; Chaput, Ludovic; Singh, Natesh; Villoutreix, Bruno O; Hafizi, Sassan.

Biochem Biophys Rep ; 30: 101263, 2022 Jul.

Artigo Inglês | MEDLINE | ID: mdl-35518197

17.

Laminin G1 residues of protein S mediate its TFPI cofactor function and are competitively regulated by C4BP.

Teraz-Orosz, Adrienn; Gierula, Magdalena; Petri, Anastasis; Jones, David; Keniyopoullos, Renos; Folgado, Patricia Badia; Santamaria, Salvatore; Crawley, James T B; Lane, David A; Ahnström, Josefin.

Blood Adv ; 6(2): 704-715, 2022 01 25.

Artigo Inglês | MEDLINE | ID: mdl-34731882

18.

A top-down approach to uncover the hidden ligandome of low-density lipoprotein receptor-related protein 1 in cartilage.

Yamamoto, Kazuhiro; Scavenius, Carsten; Meschis, Maria M; Gremida, Abdulrahman M E; Mogensen, Emilie H; Thøgersen, Ida B; Bonelli, Simone; Scilabra, Simone D; Jensen, Anders; Santamaria, Salvatore; Ahnström, Josefin; Bou-Gharios, George; Enghild, Jan J; Nagase, Hideaki.

Matrix Biol ; 112: 190-218, 2022 09.

Artigo Inglês | MEDLINE | ID: mdl-36028175

19.

Illustrated State-of-the-Art Capsules of the ISTH 2022 Congress.

Ariëns, Robert A; Hunt, Beverley J; Agbani, Ejaife O; Ahnström, Josefin; Ahrends, Robert; Alikhan, Raza; Assinger, Alice; Bagoly, Zsuzsa; Balduini, Alessandra; Barbon, Elena; Barrett, Christopher D; Batty, Paul; Carneiro, Jorge David Aivazoglou; Chan, Wee Shian; de Maat, Moniek; de Wit, Kerstin; Denis, Cécile; Ellis, Martin H; Eslick, Renee; Fu, Hongxia; Hayward, Catherine P M; Ho-Tin-Noé, Benoit; Klok, Frederikus A; Kumar, Riten; Leiderman, Karin; Litvinov, Rustem I; Mackman, Nigel; McQuilten, Zoe; Neal, Matthew D; Parker, William A E; Preston, Roger J S; Rayes, Julie; Rezaie, Alireza R; Roberts, Lara N; Rocca, Bianca; Shapiro, Susan; Siegal, Deborah M; Sousa, Lirlândia P; Suzuki-Inoue, Katsue; Zafar, Tahira; Zhou, Jiaxi.

Res Pract Thromb Haemost ; 6(5): e12747, 2022 Jul.

Artigo Inglês | MEDLINE | ID: mdl-35814801

20.

Pleiotropic anticoagulant functions of protein S, consequences for the clinical laboratory. Communication from the SSC of the ISTH.

Brinkman, Herm Jan M; Ahnström, Josefin; Castoldi, Elisabetta; Dahlbäck, Björn; Marlar, Richard A.

J Thromb Haemost ; 19(1): 281-286, 2021 01.

Artigo Inglês | MEDLINE | ID: mdl-33405384

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