Detalhe da pesquisa
1.
Design, synthesis, and biochemical and computational screening of novel oxindole derivatives as inhibitors of Aurora A kinase and SARS-CoV-2 spike/host ACE2 interaction.
Med Chem Res
; 33(4): 620-634, 2024.
Artigo
Inglês
| MEDLINE | ID: mdl-38646411
2.
Synthesis and biological evaluation of 1-phenyl-4,6-dihydrobenzo[b]pyrazolo[3,4-d]azepin-5(1H)-one/thiones as anticancer agents.
Bioorg Chem
; 135: 106478, 2023 06.
Artigo
Inglês
| MEDLINE | ID: mdl-36958121
3.
Benzimidazole-linked pyrazolo[1,5-a]pyrimidine conjugates: synthesis and detail evaluation as potential anticancer agents.
Mol Divers
; 27(3): 1185-1202, 2023 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-36114912
4.
Design, synthesis, and structure-activity studies of new rhodanine derivatives as carbonic anhydrase II, IX inhibitors.
Arch Pharm (Weinheim)
; 356(9): e2300205, 2023 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-37391391
5.
Synthesis and Antibacterial Evaluation of Rhodanine and Its Related Heterocyclic Compounds against S.â aureus and A.â baumannii.
Chem Biodivers
; 19(7): e202200213, 2022 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-35714172
6.
Synthesis and antibacterial evaluation of (E)-1-(1H-indol-3-yl) ethanone O-benzyl oxime derivatives against MRSA and VRSA strains.
Bioorg Chem
; 116: 105288, 2021 11.
Artigo
Inglês
| MEDLINE | ID: mdl-34454299
7.
Catalyst-free facile synthesis of polycyclic indole/pyrrole substituted-1,2,3-triazoles.
Org Biomol Chem
; 17(35): 8153-8165, 2019 09 21.
Artigo
Inglês
| MEDLINE | ID: mdl-31460554
8.
Synthesis of new 3-phenylquinazolin-4(3H)-one derivatives as potent antibacterial agents effective against methicillin- and vancomycin-resistant Staphylococcus aureus (MRSA and VRSA).
Bioorg Chem
; 81: 175-183, 2018 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30130650
9.
Synthesis of benzo[d]imidazo[2,1-b]thiazole-chalcone conjugates as microtubule targeting and apoptosis inducing agents.
Bioorg Chem
; 76: 1-12, 2018 02.
Artigo
Inglês
| MEDLINE | ID: mdl-29102724
10.
Corrigendum to "Synthesis of benzo[d]imidazo[2,1-b]thiazole-chalcone conjugates as microtubule targeting and apoptosis inducing agents" [Bioorg. Chem. 76 (2018) 1-12].
Bioorg Chem
; 96: 103070, 2020 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-32062062
11.
Small molecule inhibitors of NLRP3 inflammasome and GSK-3ß in the management of traumatic brain injury: A review.
Eur J Med Chem
; 259: 115718, 2023 Nov 05.
Artigo
Inglês
| MEDLINE | ID: mdl-37573828
12.
Oxiconazole Potentiates Gentamicin against Gentamicin-Resistant Staphylococcus aureus In Vitro and In Vivo.
Microbiol Spectr
; 11(4): e0503122, 2023 08 17.
Artigo
Inglês
| MEDLINE | ID: mdl-37428033
13.
Serendipitous identification of phenylhydrazine derivatives as potent inhibitors of carbapenem-resistant Acinetobacter baumannii.
Future Med Chem
; 14(22): 1621-1634, 2022 11.
Artigo
Inglês
| MEDLINE | ID: mdl-36326019
14.
Fused-azepinones: Emerging scaffolds of medicinal importance.
Eur J Med Chem
; 220: 113445, 2021 Aug 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33901899
15.
Synthesis and evaluation of new quinazoline-benzimidazole hybrids as potent anti-microbial agents against multidrug resistant Staphylococcus aureus and Mycobacterium tuberculosis.
Eur J Med Chem
; 212: 112996, 2021 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-33190958
16.
FabI (enoyl acyl carrier protein reductase) - A potential broad spectrum therapeutic target and its inhibitors.
Eur J Med Chem
; 208: 112757, 2020 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32883635
17.
Pyrazolo-benzothiazole hybrids: Synthesis, anticancer properties and evaluation of antiangiogenic activity using in vitro VEGFR-2 kinase and in vivo transgenic zebrafish model.
Eur J Med Chem
; 182: 111609, 2019 Nov 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31445229
18.
Design, synthesis and biological evaluation of new ß-carboline-bisindole compounds as DNA binding, photocleavage agents and topoisomerase I inhibitors.
Eur J Med Chem
; 143: 1563-1577, 2018 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29129513
19.
4ß-amidotriazole linked podophyllotoxin congeners: DNA topoisomerase-IIα inhibition and potential anticancer agents for prostate cancer.
Eur J Med Chem
; 144: 595-611, 2018 Jan 20.
Artigo
Inglês
| MEDLINE | ID: mdl-29289884