Detalhe da pesquisa
1.
Structure-based discovery of selective positive allosteric modulators of antagonists for the M2 muscarinic acetylcholine receptor.
Proc Natl Acad Sci U S A
; 115(10): E2419-E2428, 2018 03 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29453275
2.
Metabotropic glutamate receptor 5 (mGlu5 )-positive allosteric modulators differentially induce or potentiate desensitization of mGlu5 signaling in recombinant cells and neurons.
J Neurochem
; 151(3): 301-315, 2019 11.
Artigo
Inglês
| MEDLINE | ID: mdl-31376155
3.
"Selective" Class C G Protein-Coupled Receptor Modulators Are Neutral or Biased mGlu5 Allosteric Ligands.
Mol Pharmacol
; 93(5): 504-514, 2018 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29514854
4.
ß2-Adrenoceptors on tumor cells play a critical role in stress-enhanced metastasis in a mouse model of breast cancer.
Brain Behav Immun
; 57: 106-115, 2016 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-27321906
5.
ß2-adrenoceptor signaling regulates invadopodia formation to enhance tumor cell invasion.
Breast Cancer Res
; 17(1): 145, 2015 Nov 25.
Artigo
Inglês
| MEDLINE | ID: mdl-26607426
6.
Kinetic and system bias as drivers of metabotropic glutamate receptor 5 allosteric modulator pharmacology.
Neuropharmacology
; 149: 83-96, 2019 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30763654
7.
Structure-Based Design and Discovery of New M2 Receptor Agonists.
J Med Chem
; 60(22): 9239-9250, 2017 11 22.
Artigo
Inglês
| MEDLINE | ID: mdl-29094937