Detalhe da pesquisa
1.
Improving carcinogenicity assessment.
Toxicol Pathol
; 41(2): 263-70, 2013 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-23076039
2.
An analysis of pharmaceutical experience with decades of rat carcinogenicity testing: support for a proposal to modify current regulatory guidelines.
Toxicol Pathol
; 39(4): 716-44, 2011 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-21666103
3.
Acute lymphoid and gastrointestinal toxicity induced by selective p38alpha map kinase and map kinase-activated protein kinase-2 (MK2) inhibitors in the dog.
Toxicol Pathol
; 38(4): 606-18, 2010 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-20448081
4.
Effect of an experimental proteasome inhibitor on the cytoskeleton, cytosolic protein turnover, and induction in the neuronal cells in vitro.
Neurotoxicology
; 29(2): 232-43, 2008 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-18155769
5.
Re: analysis of pharmaceutical experience with decades of rat carcinogenicity testing. Introduction to article by Sistare et al.
Toxicol Pathol
; 39(4): 715, 2011 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-21666102
6.
The re-emergence (or the decline) of toxicologic pathology.
Toxicol Pathol
; 37(5): 570-1, 2009 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-19638439
7.
Confidence in rodent carcinogenesis bioassays.
Vet Pathol
; 46(5): 790-1, 2009 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-19429982
8.
Toxicological protein biomarker analysis--an investigative one-week single dose intravenous infusion toxicity and toxicokinetic study in cynomolgus monkeys using an antibody-cytotoxic conjugate against ovarian cancer.
Pharm Res
; 25(6): 1309-17, 2008 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-18060481
9.
Biomarkers to monitor drug-induced phospholipidosis.
Toxicol Appl Pharmacol
; 218(1): 72-8, 2007 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-17156806
10.
Drug safety evaluation through biomarker analysis--a toxicity study in the cynomolgus monkey using an antibody-cytotoxic conjugate against ovarian cancer.
Toxicol Appl Pharmacol
; 224(1): 12-8, 2007 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-17681578
11.
Differential display in rat livers treated for 13 weeks with phenobarbital implicates a role for metabolic and oxidative stress in nongenotoxic carcinogenicity.
Toxicol Pathol
; 33(1): 118-26, 2005.
Artigo
Inglês
| MEDLINE | ID: mdl-15805063
12.
Application of genetically altered models as replacement for the lifetime mouse bioassay in pharmaceutical development.
Toxicol Pathol
; 30(1): 135-8, 2002.
Artigo
Inglês
| MEDLINE | ID: mdl-11890466
13.
The Tg rasH2 mouse in cancer hazard identification.
Toxicol Pathol
; 30(1): 139-46, 2002.
Artigo
Inglês
| MEDLINE | ID: mdl-11890467
14.
Acute molecular markers of rodent hepatic carcinogenesis identified by transcription profiling.
Chem Res Toxicol
; 17(4): 463-70, 2004 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-15089088