RESUMO
AIMS: The aim of this study was to evaluate the relationship between pathological findings and clinical features in patients with ovarian mature cystic teratomas (MCTs). MATERIALS AND METHODS: We reviewed and compared the demographic and clinical features of 32 patients confirmed pathologically as having MCT at a university hospital from 2009 to 2014, with MCT contents such as skin, hair, sebum, and cartilage. RESULTS: The mean age of the patients was 33.7 ± 13.4 years. The mean tumor diameter was 7.1 ± 3.3 cm (range: 2-15 cm). The mean serum CA-19.9 level was 37.5 ± 79.5 IU/ml and the mean serum CA-125 level was 29.1 ± 33.0 IU/ml. The postmenopausal and pregnancy status rates of participants were 18.8, and 15.6%, respectively. The mean age, postmenopausal and pregnancy status, tumor size, symptoms related to MCT and laterality of the tumor did not differ among the patients according to the MCT contents. CONCLUSIONS: Our findings suggest no relationship between the clinical features and histopathological contents of MCTs.
Assuntos
Antígeno Ca-125/sangue , Antígeno CA-19-9/sangue , Neoplasias Ovarianas/patologia , Complicações Neoplásicas na Gravidez/patologia , Teratoma/patologia , Adolescente , Adulto , Idoso , Feminino , Humanos , Pessoa de Meia-Idade , Neoplasias Ovarianas/sangue , Gravidez , Complicações Neoplásicas na Gravidez/sangue , Estudos Retrospectivos , Teratoma/sangue , Adulto JovemRESUMO
The effects of 1 mg of a synthetic analogue of leu-enkephalin (Dalargin) injected intramuscular twice daily for 3 consecutive days were studied in 20 patients with alcohol withdrawal syndrome. The results suggest that the therapeutic effects of Dalargin in alcohol withdrawal syndrome are mainly connected with the changes in the dopamine-, serotonin-, GABA- and opioid-ergic neurotransmitters systems.
Assuntos
Leucina Encefalina-2-Alanina/análogos & derivados , Etanol/efeitos adversos , Síndrome de Abstinência a Substâncias/tratamento farmacológico , Simpatolíticos/administração & dosagem , Hormônio Adrenocorticotrópico/sangue , Adulto , Dopamina/sangue , Leucina Encefalina-2-Alanina/administração & dosagem , Humanos , Masculino , Serotonina/sangue , Síndrome de Abstinência a Substâncias/sangue , Ácido gama-Aminobutírico/sangueRESUMO
Plasma levels of excitatory and inhibitory amino acid neurotransmitters were assayed in 20 male patients following alcohol withdrawal and in 20 normal controls. All patients filled out an 'Alcohol withdrawal symptom monitoring sheet', including more than 20 symptoms. The levels of excitatory amino acid were higher and the values of inhibitory amino acid lower in the patients than in the controls. The correlation between the level of excitatory amino acid and the rating of subjective discomfort was positive, and the correlation between the level of inhibitory amino acid and the level of subjective discomfort was negative.