Detalhe da pesquisa
1.
GLI1 interaction with p300 modulates SDF1 expression in cancer-associated fibroblasts to promote pancreatic cancer cells migration.
Biochem J
; 480(3): 225-241, 2023 02 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36734208
2.
SUFU promotes GLI activity in a Hedgehog-independent manner in pancreatic cancer.
Biochem J
; 480(15): 1199-1216, 2023 08 16.
Artigo
Inglês
| MEDLINE | ID: mdl-37477952
3.
A rare germline CDKN2A variant (47T>G; p16-L16R) predisposes carriers to pancreatic cancer by reducing cell cycle inhibition.
J Biol Chem
; 296: 100634, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33823155
4.
TFII-I-mediated polymerase pausing antagonizes GLI2 induction by TGFß.
Nucleic Acids Res
; 48(13): 7169-7181, 2020 07 27.
Artigo
Inglês
| MEDLINE | ID: mdl-32544250
5.
The transcription factor GLI1 cooperates with the chromatin remodeler SMARCA2 to regulate chromatin accessibility at distal DNA regulatory elements.
J Biol Chem
; 295(26): 8725-8735, 2020 06 26.
Artigo
Inglês
| MEDLINE | ID: mdl-32376693
6.
The extracellular sulfatase SULF2 promotes liver tumorigenesis by stimulating assembly of a promoter-looping GLI1-STAT3 transcriptional complex.
J Biol Chem
; 295(9): 2698-2712, 2020 02 28.
Artigo
Inglês
| MEDLINE | ID: mdl-31988246
7.
GLI1/GLI2 functional interplay is required to control Hedgehog/GLI targets gene expression.
Biochem J
; 477(17): 3131-3145, 2020 09 18.
Artigo
Inglês
| MEDLINE | ID: mdl-32766732
8.
Targeting of the Hedgehog/GLI and mTOR pathways in advanced pancreatic cancer, a phase 1 trial of Vismodegib and Sirolimus combination.
Pancreatology
; 20(6): 1115-1122, 2020 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-32778368
9.
Phase 1 trial of Vismodegib and Erlotinib combination in metastatic pancreatic cancer.
Pancreatology
; 20(1): 101-109, 2020 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-31787526
10.
Lysine methyltransferase 2D regulates pancreatic carcinogenesis through metabolic reprogramming.
Gut
; 68(7): 1271-1286, 2019 07.
Artigo
Inglês
| MEDLINE | ID: mdl-30337373
11.
Stromal Gli signaling regulates the activity and differentiation of prostate stem and progenitor cells.
J Biol Chem
; 293(27): 10547-10560, 2018 07 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29773652
12.
4EBP1/c-MYC/PUMA and NF-κB/EGR1/BIM pathways underlie cytotoxicity of mTOR dual inhibitors in malignant lymphoid cells.
Blood
; 127(22): 2711-22, 2016 06 02.
Artigo
Inglês
| MEDLINE | ID: mdl-26917778
13.
Nuclear Factor of Activated T Cells-dependent Down-regulation of the Transcription Factor Glioma-associated Protein 1 (GLI1) Underlies the Growth Inhibitory Properties of Arachidonic Acid.
J Biol Chem
; 291(4): 1933-1947, 2016 Jan 22.
Artigo
Inglês
| MEDLINE | ID: mdl-26601952
14.
The oncogenic transcription factor IRF4 is regulated by a novel CD30/NF-κB positive feedback loop in peripheral T-cell lymphoma.
Blood
; 125(20): 3118-27, 2015 May 14.
Artigo
Inglês
| MEDLINE | ID: mdl-25833963
15.
Modulation of the IL-6 Receptor α Underlies GLI2-Mediated Regulation of Ig Secretion in Waldenström Macroglobulinemia Cells.
J Immunol
; 195(6): 2908-16, 2015 Sep 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26238488
16.
Identification and characterization of a novel promoter for the human ANO1 gene regulated by the transcription factor signal transducer and activator of transcription 6 (STAT6).
FASEB J
; 29(1): 152-63, 2015 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-25351986
17.
Bmi1 is required for the initiation of pancreatic cancer through an Ink4a-independent mechanism.
Carcinogenesis
; 36(7): 730-8, 2015 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-25939753
18.
The transcription factor GLI1 interacts with SMAD proteins to modulate transforming growth factor ß-induced gene expression in a p300/CREB-binding protein-associated factor (PCAF)-dependent manner.
J Biol Chem
; 289(22): 15495-506, 2014 May 30.
Artigo
Inglês
| MEDLINE | ID: mdl-24739390
19.
Loss of the transcription factor GLI1 identifies a signaling network in the tumor microenvironment mediating KRAS oncogene-induced transformation.
J Biol Chem
; 288(17): 11786-94, 2013 Apr 26.
Artigo
Inglês
| MEDLINE | ID: mdl-23482563
20.
Activation of the transcription factor GLI1 by WNT signaling underlies the role of SULFATASE 2 as a regulator of tissue regeneration.
J Biol Chem
; 288(29): 21389-21398, 2013 Jul 19.
Artigo
Inglês
| MEDLINE | ID: mdl-23740243