Aviation for the People: Class and State Aviation in Perón's "New Argentina," 1946-55.

This article investigates the culture and politics of aviation in mid-twentieth-century Argentina under Juan D. Perón's populist government. For enthusiasts around the world, aviation seemed poised for the long-prophesized "Air Age" transformations. Most emphasized the middle-class or elite nature of this quintessentially modern industry and its customers. Recent aviation scholarship in Europe and the United States has thus focused on affluent passengers or aircraft owners as the consumers of aviation technology. But this article reveals that Peronist Argentina implemented a massive political aviation program aimed at elevating socioeconomic conditions for the working classes. State media show that the authorities harnessed aviation as a technopolitical tool to both represent and enact their vision for a "New Argentina" by providing "dignified" work for the lower classes.

Unravelling the molecular interactions between the SARS-CoV-2 RBD spike protein and various specific monoclonal antibodies.

Vaccination against SARS-CoV-2 just started in most of the countries. However, the development of specific vaccines against SARS-CoV-2 is not the only approach to control the virus and monoclonal antibodies (mAbs) start to merit special attention as a therapeutic option to treat COVID-19 disease. Here, the main conformations and interactions between the receptor-binding domain (RBD) of spike glycoprotein of SARS-CoV-2 (S protein) with two mAbs (CR3022 and S309) and the ACE2 cell receptor are studied as the main representatives of three different epitopes on the RBD of S protein. The combined approach of 1 µs accelerated molecular dynamics (aMD) and ab-initio hybrid molecular dynamics is used to identify the most predominant interactions under physiological conditions. Results allow to determine the main receptor-binding mapping, hydrogen bonding network and salt bridges in the most populated antigen-antibody interface conformations. The deep knowledge on the protein-protein interactions involving mAbs and ACE2 receptor with the spike glycoprotein of SARS-CoV-2 increases background knowledge to speed up the development of new vaccines and therapeutic drugs.