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1.
Nature ; 583(7816): 385-390, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-32669694

RESUMO

High-speed actuation of laser frequency1 is critical in applications using lasers and frequency combs2,3, and is a prerequisite for phase locking, frequency stabilization and stability transfer among optical carriers. For example, high-bandwidth feedback control of frequency combs is used in optical-frequency synthesis4, frequency division5 and optical clocks6. Soliton microcombs7,8 have emerged as chip-scale frequency comb sources, and have been used in system-level demonstrations9,10. Yet integrated microcombs using thermal heaters have limited actuation bandwidths11,12 of up to 10 kilohertz. Consequently, megahertz-bandwidth actuation and locking of microcombs have only been achieved with off-chip bulk component modulators. Here we demonstrate high-speed soliton microcomb actuation using integrated piezoelectric components13. By monolithically integrating AlN actuators14 on ultralow-loss Si3N4 photonic circuits15, we demonstrate voltage-controlled soliton initiation, tuning and stabilization with megahertz bandwidth. The AlN actuators use 300 nanowatts of power and feature bidirectional tuning, high linearity and low hysteresis. They exhibit a flat actuation response up to 1 megahertz-substantially exceeding bulk piezo tuning bandwidth-that is extendable to higher frequencies by overcoming coupling to acoustic contour modes of the chip. Via synchronous tuning of the laser and the microresonator, we exploit this ability to frequency-shift the optical comb spectrum (that is, to change the comb's carrier-envelope offset frequency) and make excursions beyond the soliton existence range. This enables a massively parallel frequency-modulated engine16,17 for lidar (light detection and ranging), with increased frequency excursion, lower power and elimination of channel distortions resulting from the soliton Raman self-frequency shift. Moreover, by modulating at a rate matching the frequency of high-overtone bulk acoustic resonances18, resonant build-up of bulk acoustic energy allows a 14-fold reduction of the required driving voltage, making it compatible with CMOS (complementary metal-oxide-semiconductor) electronics. Our approach endows soliton microcombs with integrated, ultralow-power and fast actuation, expanding the repertoire of technological applications of microcombs.

2.
Nature ; 546(7657): 274-279, 2017 06 07.
Artigo em Inglês | MEDLINE | ID: mdl-28593968

RESUMO

Solitons are waveforms that preserve their shape while propagating, as a result of a balance of dispersion and nonlinearity. Soliton-based data transmission schemes were investigated in the 1980s and showed promise as a way of overcoming the limitations imposed by dispersion of optical fibres. However, these approaches were later abandoned in favour of wavelength-division multiplexing schemes, which are easier to implement and offer improved scalability to higher data rates. Here we show that solitons could make a comeback in optical communications, not as a competitor but as a key element of massively parallel wavelength-division multiplexing. Instead of encoding data on the soliton pulse train itself, we use continuous-wave tones of the associated frequency comb as carriers for communication. Dissipative Kerr solitons (DKSs) (solitons that rely on a double balance of parametric gain and cavity loss, as well as dispersion and nonlinearity) are generated as continuously circulating pulses in an integrated silicon nitride microresonator via four-photon interactions mediated by the Kerr nonlinearity, leading to low-noise, spectrally smooth, broadband optical frequency combs. We use two interleaved DKS frequency combs to transmit a data stream of more than 50 terabits per second on 179 individual optical carriers that span the entire telecommunication C and L bands (centred around infrared telecommunication wavelengths of 1.55 micrometres). We also demonstrate coherent detection of a wavelength-division multiplexing data stream by using a pair of DKS frequency combs-one as a multi-wavelength light source at the transmitter and the other as the corresponding local oscillator at the receiver. This approach exploits the scalability of microresonator-based DKS frequency comb sources for massively parallel optical communications at both the transmitter and the receiver. Our results demonstrate the potential of these sources to replace the arrays of continuous-wave lasers that are currently used in high-speed communications. In combination with advanced spatial multiplexing schemes and highly integrated silicon photonic circuits, DKS frequency combs could bring chip-scale petabit-per-second transceivers into reach.

3.
Phys Rev Lett ; 120(5): 053902, 2018 Feb 02.
Artigo em Inglês | MEDLINE | ID: mdl-29481150

RESUMO

Temporal cavity solitons (CS) are optical pulses that can persist in passive resonators, and they play a key role in the generation of coherent microresonator frequency combs. In resonators made of amorphous materials, such as fused silica, they can exhibit a spectral redshift due to stimulated Raman scattering. Here we show that this Raman-induced self-frequency-shift imposes a fundamental limit on the duration and bandwidth of temporal CSs. Specifically, we theoretically predict that stimulated Raman scattering introduces a previously unidentified Hopf bifurcation that leads to destabilization of CSs at large pump-cavity detunings, limiting the range of detunings over which they can exist. We have confirmed our theoretical predictions by performing extensive experiments in synchronously driven fiber ring resonators, obtaining results in excellent agreement with numerical simulations. Our results could have significant implications for the future design of Kerr frequency comb systems based on amorphous microresonators.

4.
Nat Commun ; 14(1): 3499, 2023 Jun 13.
Artigo em Inglês | MEDLINE | ID: mdl-37311746

RESUMO

The availability of thin-film lithium niobate on insulator (LNOI) and advances in processing have led to the emergence of fully integrated LiNbO3 electro-optic devices. Yet to date, LiNbO3 photonic integrated circuits have mostly been fabricated using non-standard etching techniques and partially etched waveguides, that lack the reproducibility achieved in silicon photonics. Widespread application of thin-film LiNbO3 requires a reliable solution with precise lithographic control. Here we demonstrate a heterogeneously integrated LiNbO3 photonic platform employing wafer-scale bonding of thin-film LiNbO3 to silicon nitride (Si3N4) photonic integrated circuits. The platform maintains the low propagation loss (<0.1 dB/cm) and efficient fiber-to-chip coupling (<2.5 dB per facet) of the Si3N4 waveguides and provides a link between passive Si3N4 circuits and electro-optic components with adiabatic mode converters experiencing insertion losses below 0.1 dB. Using this approach we demonstrate several key applications, thus providing a scalable, foundry-ready solution to complex LiNbO3 integrated photonic circuits.

5.
Nat Commun ; 13(1): 4764, 2022 Aug 13.
Artigo em Inglês | MEDLINE | ID: mdl-35963859

RESUMO

Solitons are shape preserving waveforms that are ubiquitous across nonlinear dynamical systems from BEC to hydrodynamics, and fall into two separate classes: bright solitons existing in anomalous group velocity dispersion, and switching waves forming 'dark solitons' in normal dispersion. Bright solitons in particular have been relevant to chip-scale microresonator frequency combs, used in applications across communications, metrology, and spectroscopy. Both have been studied, yet the existence of a structure between this dichotomy has only been theoretically predicted. We report the observation of dissipative structures embodying a hybrid between switching waves and dissipative solitons, existing in the regime of vanishing group velocity dispersion where third-order dispersion is dominant, hence termed as 'zero-dispersion solitons'. They are observed to arise from the interlocking of two modulated switching waves, forming a stable solitary structure consisting of a quantized number of peaks. The switching waves form directly via synchronous pulse-driving of a Si3N4 microresonator. The resulting comb spectrum spans 136 THz or 97% of an octave, further enhanced by higher-order dispersive wave formation. This dissipative structure expands the domain of Kerr cavity physics to the regime near to zero-dispersion and could present a superior alternative to conventional solitons for broadband comb generation.

6.
Nat Commun ; 13(1): 1771, 2022 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-35365647

RESUMO

The past decade has witnessed major advances in the development and system-level applications of photonic integrated microcombs, that are coherent, broadband optical frequency combs with repetition rates in the millimeter-wave to terahertz domain. Most of these advances are based on harnessing of dissipative Kerr solitons (DKS) in microresonators with anomalous group velocity dispersion (GVD). However, microcombs can also be generated with normal GVD using localized structures that are referred to as dark pulses, switching waves or platicons. Compared with DKS microcombs that require specific designs and fabrication techniques for dispersion engineering, platicon microcombs can be readily built using CMOS-compatible platforms such as thin-film (i.e., thickness below 300 nm) silicon nitride with normal GVD. Here, we use laser self-injection locking to demonstrate a fully integrated platicon microcomb operating at a microwave K-band repetition rate. A distributed feedback (DFB) laser edge-coupled to a Si3N4 chip is self-injection-locked to a high-Q ( > 107) microresonator with high confinement waveguides, and directly excites platicons without sophisticated active control. We demonstrate multi-platicon states and switching, perform optical feedback phase study and characterize the phase noise of the K-band platicon repetition rate and the pump laser. Laser self-injection-locked platicons could facilitate the wide adoption of microcombs as a building block in photonic integrated circuits via commercial foundry service.

7.
Healthc Financ Manage ; 48(9): 58-61, 1994 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-10146064

RESUMO

Business survival is increasingly difficult in the contemporary world. In order to survive, organizations need a commitment to excellence and a means of measuring that commitment and its results. Benchmarking provides one method for doing this. As the author describes, benchmarking is a performance improvement method that has been used for centuries. Recently, it has begun to be used in the healthcare industry where it has the potential to improve significantly the efficiency, cost-effectiveness, and quality of healthcare services.


Assuntos
Competição Econômica/organização & administração , Gestão da Qualidade Total/normas , Comércio/economia , Comércio/normas , Comunicação , Coleta de Dados/métodos , Humanos , Objetivos Organizacionais , Técnicas de Planejamento , Gestão da Qualidade Total/economia , Estados Unidos
9.
Artigo em Inglês | MEDLINE | ID: mdl-9192576

RESUMO

With a careful cost-restructuring plan based on benchmark information, The Foster G. McGaw Hospital of Loyola University reduced its operating budget by $33 million and put in place the structure for sustained progress in cost reduction.


Assuntos
Centros Médicos Acadêmicos/normas , Reestruturação Hospitalar/organização & administração , Gestão da Qualidade Total/métodos , Centros Médicos Acadêmicos/organização & administração , Orçamentos , Chicago , Controle de Custos , Humanos
10.
J Am Chem Soc ; 125(16): 4700-1, 2003 Apr 23.
Artigo em Inglês | MEDLINE | ID: mdl-12696875

RESUMO

The ability of peptide-modified gold nanoparticles to target the nucleus of HepG2 cells was explored. Five peptide/nanoparticle complexes were investigated, particles modified with (1) the nuclear localization signal (NLS) from the SV 40 virus; (2) the adenovirus NLS; (3) the adenovirus receptor-mediated endocytosis (RME) peptide; (4) one long peptide containing the adenovirus RME and NLS; and (5) the adenovirus RME and NLS peptides attached to the nanoparticle as separate pieces. Gold nanoparticles were used because they are easy to identify using video-enhanced color differential interference contrast microscopy, and they are excellent scaffolds from which to build multifunctional nuclear targeting vectors. For example, particles modified solely with NLS peptides were not able to target the nucleus of HepG2 cells from outside the plasma membrane, because they either could not enter the cell or were trapped in endosomes. The combination of NLS/RME particles (4) and (5) did reach the nucleus; however, nuclear targeting was more efficient when the two signals were attached to nanoparticles as separate short pieces versus one long peptide. These studies highlight the challenges associated with nuclear targeting and the potential advantages of designing multifunctional nanostructured materials as tools for intracellular diagnostics and therapeutic delivery.


Assuntos
Núcleo Celular/metabolismo , Ouro/química , Ouro/farmacocinética , Oligopeptídeos/química , Oligopeptídeos/farmacocinética , Sequência de Aminoácidos , Humanos , Dados de Sequência Molecular , Nanotecnologia/métodos , Tamanho da Partícula , Soroalbumina Bovina/química , Soroalbumina Bovina/farmacocinética , Células Tumorais Cultivadas
11.
Springfield; Charles C. Thomas; 1965. 460 p. ilus, 29cm.
Monografia em Inglês | SES-SP, SES SP = Acervo Instituto Lauro de Souza Lima, SES-SP | ID: biblio-1085321
12.
Springfield; Charles C. Thomas; 1958. 463 p. ilus, ^e29cm.
Monografia em Inglês | SES-SP, SES SP = Acervo Instituto Lauro de Souza Lima, SES-SP | ID: biblio-1085344
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