Pesquisa | Secretaria de Estado da Saúde

1.

Sensing Cytosolic DNA Lowers Blood Pressure by Direct cGAMP-Dependent PKGI Activation.

Su, Jie; Coleman, Pierre; Ntorla, Angeliki; Anderson, Rhys; Shattock, Michael J; Burgoyne, Joseph R.

Circulation ; 148(13): 1023-1034, 2023 09 26.

Artigo Inglês | MEDLINE | ID: mdl-37548012

2.

Length-independent telomere damage drives post-mitotic cardiomyocyte senescence.

Anderson, Rhys; Lagnado, Anthony; Maggiorani, Damien; Walaszczyk, Anna; Dookun, Emily; Chapman, James; Birch, Jodie; Salmonowicz, Hanna; Ogrodnik, Mikolaj; Jurk, Diana; Proctor, Carole; Correia-Melo, Clara; Victorelli, Stella; Fielder, Edward; Berlinguer-Palmini, Rolando; Owens, Andrew; Greaves, Laura C; Kolsky, Kathy L; Parini, Angelo; Douin-Echinard, Victorine; LeBrasseur, Nathan K; Arthur, Helen M; Tual-Chalot, Simon; Schafer, Marissa J; Roos, Carolyn M; Miller, Jordan D; Robertson, Neil; Mann, Jelena; Adams, Peter D; Tchkonia, Tamara; Kirkland, James L; Mialet-Perez, Jeanne; Richardson, Gavin D; Passos, João F.

EMBO J ; 38(5)2019 03 01.

Artigo Inglês | MEDLINE | ID: mdl-30737259

3.

Mitochondria are required for pro-ageing features of the senescent phenotype.

Correia-Melo, Clara; Marques, Francisco D M; Anderson, Rhys; Hewitt, Graeme; Hewitt, Rachael; Cole, John; Carroll, Bernadette M; Miwa, Satomi; Birch, Jodie; Merz, Alina; Rushton, Michael D; Charles, Michelle; Jurk, Diana; Tait, Stephen W G; Czapiewski, Rafal; Greaves, Laura; Nelson, Glyn; Bohlooly-Y, Mohammad; Rodriguez-Cuenca, Sergio; Vidal-Puig, Antonio; Mann, Derek; Saretzki, Gabriele; Quarato, Giovanni; Green, Douglas R; Adams, Peter D; von Zglinicki, Thomas; Korolchuk, Viktor I; Passos, João F.

EMBO J ; 35(7): 724-42, 2016 Apr 01.

Artigo Inglês | MEDLINE | ID: mdl-26848154

4.

Conductivity Spectrum of Ultracold Atoms in an Optical Lattice.

Anderson, Rhys; Wang, Fudong; Xu, Peihang; Venu, Vijin; Trotzky, Stefan; Chevy, Frédéric; Thywissen, Joseph H.

Phys Rev Lett ; 122(15): 153602, 2019 Apr 19.

Artigo Inglês | MEDLINE | ID: mdl-31050527

5.

JNK/SAPK Signaling Is Essential for Efficient Reprogramming of Human Fibroblasts to Induced Pluripotent Stem Cells.

Neganova, Irina; Shmeleva, Evgenija; Munkley, Jennifer; Chichagova, Valeria; Anyfantis, George; Anderson, Rhys; Passos, Joao; Elliott, David J; Armstrong, Lyle; Lako, Majlinda.

Stem Cells ; 34(5): 1198-212, 2016 05.

Artigo Inglês | MEDLINE | ID: mdl-26867034

6.

DNA damage response at telomeres contributes to lung aging and chronic obstructive pulmonary disease.

Birch, Jodie; Anderson, Rhys K; Correia-Melo, Clara; Jurk, Diana; Hewitt, Graeme; Marques, Francisco Madeira; Green, Nicola J; Moisey, Elizabeth; Birrell, Mark A; Belvisi, Maria G; Black, Fiona; Taylor, John J; Fisher, Andrew J; De Soyza, Anthony; Passos, João F.

Am J Physiol Lung Cell Mol Physiol ; 309(10): L1124-37, 2015 Nov 15.

Artigo Inglês | MEDLINE | ID: mdl-26386121

7.

Simulation of a medical linear accelerator for teaching purposes.

Anderson, Rhys; Lamey, Michael; MacPherson, Miller; Carlone, Marco.

J Appl Clin Med Phys ; 16(3): 5139, 2015 May 08.

Artigo Inglês | MEDLINE | ID: mdl-26103478

8.

Telomere Dysfunction and Senescence-associated Pathways in Bronchiectasis.

Birch, Jodie; Victorelli, Stella; Rahmatika, Dina; Anderson, Rhys K; Jiwa, Kasim; Moisey, Elizabeth; Ward, Chris; Fisher, Andrew J; De Soyza, Anthony; Passos, João F.

Am J Respir Crit Care Med ; 193(8): 929-32, 2016 Apr 15.

Artigo Inglês | MEDLINE | ID: mdl-27082536

9.

The Longevist.

Anderson, Rhys.

Rejuvenation Res ; 26(6): 255-256, 2023 Dec.

Artigo Inglês | MEDLINE | ID: mdl-37981799

10.

Mechanisms driving the ageing heart.

Anderson, Rhys; Richardson, Gavin D; Passos, João F.

Exp Gerontol ; 109: 5-15, 2018 08.

Artigo Inglês | MEDLINE | ID: mdl-29054534

11.

The TAB1-p38α complex aggravates myocardial injury and can be targeted by small molecules.

De Nicola, Gian F; Bassi, Rekha; Nichols, Charlie; Fernandez-Caggiano, Mariana; Golforoush, Pelin Arabacilar; Thapa, Dibesh; Anderson, Rhys; Martin, Eva Denise; Verma, Sharwari; Kleinjung, Jens; Laing, Adam; Hutchinson, Jonathan P; Eaton, Philip; Clark, James; Marber, Michael S.

JCI Insight ; 3(16)2018 08 23.

Artigo Inglês | MEDLINE | ID: mdl-30135318

12.

Nuclear translocation of FGFR1 and FGF2 in pancreatic stellate cells facilitates pancreatic cancer cell invasion.

Coleman, Stacey J; Chioni, Athina-Myrto; Ghallab, Mohammed; Anderson, Rhys K; Lemoine, Nicholas R; Kocher, Hemant M; Grose, Richard P.

EMBO Mol Med ; 6(4): 467-81, 2014 04.

Artigo Inglês | MEDLINE | ID: mdl-24503018

13.

Chronic inflammation induces telomere dysfunction and accelerates ageing in mice.

Jurk, Diana; Wilson, Caroline; Passos, João F; Oakley, Fiona; Correia-Melo, Clara; Greaves, Laura; Saretzki, Gabriele; Fox, Chris; Lawless, Conor; Anderson, Rhys; Hewitt, Graeme; Pender, Sylvia Lf; Fullard, Nicola; Nelson, Glyn; Mann, Jelena; van de Sluis, Bart; Mann, Derek A; von Zglinicki, Thomas.

Nat Commun ; 2: 4172, 2014 Jun 24.

Artigo Inglês | MEDLINE | ID: mdl-24960204

14.

Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence.

Hewitt, Graeme; Jurk, Diana; Marques, Francisco D M; Correia-Melo, Clara; Hardy, Timothy; Gackowska, Agata; Anderson, Rhys; Taschuk, Morgan; Mann, Jelena; Passos, João F.

Nat Commun ; 3: 708, 2012 Feb 28.

Artigo Inglês | MEDLINE | ID: mdl-22426229

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