Large-Scale Standardized Image Integration for Secondary Use Research Projects.

Imaging techniques are a cornerstone of today's medicine and can be crucial for a successful therapy. But in addition, the generated imaging series are an important resource for new informatics' methods, especially in the field of artificial intelligence. This paper describes the success of integrating clinical routine imaging data into a standardized format for research purposes. Thus, we designed an integration flow and successfully implemented it in the local data integration center of University Hospital Schleswig-Holstein. The flow integrates imaging series and radiological reports from the primary system into an openEHR repository with enrichment by semantic codes for better findability and retrieval using HL7 FHIR. As a result, 6.6 million radiological studies with 29 million image series are now available for further medical (informatics) research.

Interdisciplinary Teams in Health Informatics: Using FHIR Standards to Share Computable Knowledge.

The use and shareability of Clinical Quality Language (CQL) artefacts is an important aspect in enabling the exchange and interoperability of clinical data to support both clinical decisions and research in the medical informatics field. This paper, while basing on use cases and synthetic data, developed purposeful CQL reusable libraries to showcase the possibilities of multidisciplinary teams and how CQLs could be best used to support clinical decision making.

Strategies and Recommendation for Data Loading of FHIR-Based Data Marts with Focus on GDPR Compliance.

Interoperability and portability of healthcare data to enable research in the healthcare sector is an important factor towards precision medicine and a learning health system. With many safety-nets put in place like the European General Data Protection Regulation, and local standards like the broad consent set up by the German Medical Informatics Initiative, management and compliance to these standards across all systems and clinical data repositories becomes a daunting task. An appropriate process needs to be established especially when patient data is transferred to and from different systems and standards. On extraction and transforming, an appropriate method of loading the modified data to a destination where it can be read and accessed needs to be established besides functional compliance by the repository systems. This paper makes recommendations in relation to data load strategies while working with FHIR server-based data marts.