Detalhe da pesquisa
1.
A SMAD1/5-YAP signalling module drives radial glia self-amplification and growth of the developing cerebral cortex.
Development
; 147(13)2020 07 13.
Artigo
Inglês
| MEDLINE | ID: mdl-32541003
2.
DYRK1A modulates c-MET in pancreatic ductal adenocarcinoma to drive tumour growth.
Gut
; 68(8): 1465-1476, 2019 08.
Artigo
Inglês
| MEDLINE | ID: mdl-30343272
3.
Impaired development of neocortical circuits contributes to the neurological alterations in DYRK1A haploinsufficiency syndrome.
Neurobiol Dis
; 127: 210-222, 2019 07.
Artigo
Inglês
| MEDLINE | ID: mdl-30831192
4.
Triplication of DYRK1A causes retinal structural and functional alterations in Down syndrome.
Hum Mol Genet
; 22(14): 2775-84, 2013 Jul 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23512985
5.
Dyrk1a haploinsufficiency induces diabetes in mice through decreased pancreatic beta cell mass.
Diabetologia
; 57(5): 960-9, 2014 May.
Artigo
Inglês
| MEDLINE | ID: mdl-24477974
6.
Over-expression of RCAN1 causes Down syndrome-like hippocampal deficits that alter learning and memory.
Hum Mol Genet
; 21(13): 3025-41, 2012 Jul 01.
Artigo
Inglês
| MEDLINE | ID: mdl-22511596
7.
Upregulation of RCAN1 causes Down syndrome-like immune dysfunction.
J Med Genet
; 50(7): 444-54, 2013 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-23644448
8.
Gene expression analysis of the embryonic subplate.
Cereb Cortex
; 22(6): 1343-59, 2012 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-21862448
9.
Impaired macroglial development and axonal conductivity contributes to the neuropathology of DYRK1A-related intellectual disability syndrome.
Sci Rep
; 12(1): 19912, 2022 11 19.
Artigo
Inglês
| MEDLINE | ID: mdl-36402907
10.
DSCR1/RCAN1 regulates vesicle exocytosis and fusion pore kinetics: implications for Down syndrome and Alzheimer's disease.
Hum Mol Genet
; 17(7): 1020-30, 2008 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-18180251
11.
Age-associated motor and visuo-spatial learning phenotype in Dyrk1A heterozygous mutant mice.
Neurobiol Dis
; 36(2): 312-9, 2009 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-19660545
12.
Automated Macro Approach to Quantify Synapse Density in 2D Confocal Images from Fixed Immunolabeled Neural Tissue Sections.
Methods Mol Biol
; 2040: 71-97, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31432476
13.
DYRK1A and cognition: A lifelong relationship.
Pharmacol Ther
; 194: 199-221, 2019 02.
Artigo
Inglês
| MEDLINE | ID: mdl-30268771
14.
Efficient and specific transduction of cochlear supporting cells by adeno-associated virus serotype 5.
Neurosci Lett
; 442(2): 134-9, 2008 Sep 12.
Artigo
Inglês
| MEDLINE | ID: mdl-18601973
15.
DYRK1A Kinase Positively Regulates Angiogenic Responses in Endothelial Cells.
Cell Rep
; 23(6): 1867-1878, 2018 05 08.
Artigo
Inglês
| MEDLINE | ID: mdl-29742440
16.
Dyrk1A haploinsufficiency affects viability and causes developmental delay and abnormal brain morphology in mice.
Mol Cell Biol
; 22(18): 6636-47, 2002 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-12192061
17.
Expression profiles of the connexin genes, Gjb1 and Gjb3, in the developing mouse cochlea.
Mech Dev
; 119 Suppl 1: S111-5, 2002 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-14516671
18.
Abnormal mineralization of the Ts65Dn Down syndrome mouse appendicular skeleton begins during embryonic development in a Dyrk1a-independent manner.
Mech Dev
; 136: 133-42, 2015 May.
Artigo
Inglês
| MEDLINE | ID: mdl-25556111
19.
DYRK1A-mediated Cyclin D1 Degradation in Neural Stem Cells Contributes to the Neurogenic Cortical Defects in Down Syndrome.
EBioMedicine
; 2(2): 120-34, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-26137553
20.
Expression profiles of the connexin genes, Gjb1 and Gjb3, in the developing mouse cochlea.
Gene Expr Patterns
; 2(1-2): 113-7, 2002 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-12617848