Detalhe da pesquisa
1.
RKIP localizes to the nucleus through a bipartite nuclear localization signal and interaction with importin α to regulate mitotic progression.
J Biol Chem
; 299(4): 103023, 2023 04.
Artigo
Inglês
| MEDLINE | ID: mdl-36805338
2.
Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer.
Nature
; 559(7715): 637-641, 2018 07.
Artigo
Inglês
| MEDLINE | ID: mdl-30022161
3.
Regulation of TET2 gene expression and 5mC oxidation in breast cancer cells by estrogen signaling.
Biochem Biophys Res Commun
; 589: 240-246, 2022 01 22.
Artigo
Inglês
| MEDLINE | ID: mdl-34929447
4.
Risk factors for mortality in patients with acute bacterial cholangitis - Type-2 diabetes is a significant clinical predictor.
Rev Esp Enferm Dig
; 114(1): 59-61, 2022 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-34470460
5.
Functional role and therapeutic targeting of p21-activated kinase 4 in multiple myeloma.
Blood
; 129(16): 2233-2245, 2017 04 20.
Artigo
Inglês
| MEDLINE | ID: mdl-28096095
6.
Recurrent mutations of the exportin 1 gene (XPO1) and their impact on selective inhibitor of nuclear export compounds sensitivity in primary mediastinal B-cell lymphoma.
Am J Hematol
; 91(9): 923-30, 2016 09.
Artigo
Inglês
| MEDLINE | ID: mdl-27312795
7.
Tumour suppressor TET2 safeguards enhancers from aberrant DNA methylation and epigenetic reprogramming in ERα-positive breast cancer cells.
Epigenetics
; 17(10): 1180-1194, 2022 10.
Artigo
Inglês
| MEDLINE | ID: mdl-34689714
8.
Small Molecule Inhibitors of Nuclear Export and the Amelioration of Lupus by Modulation of Plasma Cell Generation and Survival.
Arthritis Rheumatol
; 74(8): 1363-1375, 2022 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35333447
9.
Diversity through a branched reaction pathway: generation of multicyclic scaffolds and identification of antimigratory agents.
Chemistry
; 17(2): 649-54, 2011 Jan 10.
Artigo
Inglês
| MEDLINE | ID: mdl-21207585
10.
Selinexor Sensitizes TRAIL-R2-Positive TNBC Cells to the Activity of TRAIL-R2xCD3 Bispecific Antibody.
Cells
; 9(10)2020 10 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33023194
11.
Venetoclax response is enhanced by selective inhibitor of nuclear export compounds in hematologic malignancies.
Blood Adv
; 4(3): 586-598, 2020 02 11.
Artigo
Inglês
| MEDLINE | ID: mdl-32045477
12.
Epigenetic signatures of methylated DNA cytosine in Alzheimer's disease.
Sci Adv
; 5(8): eaaw2880, 2019 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31489368
13.
Correction: Pharmacological treatment with inhibitors of nuclear export enhances the antitumor activity of docetaxel in human prostate cancer.
Oncotarget
; 10(59): 6393-6395, 2019 Oct 29.
Artigo
Inglês
| MEDLINE | ID: mdl-31695847
14.
Selinexor reduces the expression of DNA damage repair proteins and sensitizes cancer cells to DNA damaging agents.
Oncotarget
; 9(56): 30773-30786, 2018 Jul 20.
Artigo
Inglês
| MEDLINE | ID: mdl-30112106
15.
FoxO-1 contributes to the efficacy of the combination of the XPO1 inhibitor selinexor and cisplatin in ovarian carcinoma preclinical models.
Biochem Pharmacol
; 147: 93-103, 2018 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29155058
16.
Selinexor synergizes with dexamethasone to repress mTORC1 signaling and induce multiple myeloma cell death.
Oncotarget
; 9(39): 25529-25544, 2018 May 22.
Artigo
Inglês
| MEDLINE | ID: mdl-29876006
17.
Targeting the XPO1-dependent nuclear export of E2F7 reverses anthracycline resistance in head and neck squamous cell carcinomas.
Sci Transl Med
; 10(447)2018 06 27.
Artigo
Inglês
| MEDLINE | ID: mdl-29950445
18.
Down-regulation of AR splice variants through XPO1 suppression contributes to the inhibition of prostate cancer progression.
Oncotarget
; 9(82): 35327-35342, 2018 Oct 19.
Artigo
Inglês
| MEDLINE | ID: mdl-30450161
19.
Leukemogenic nucleophosmin mutation disrupts the transcription factor hub that regulates granulomonocytic fates.
J Clin Invest
; 128(10): 4260-4279, 2018 10 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30015632
20.
Pharmacological treatment with inhibitors of nuclear export enhances the antitumor activity of docetaxel in human prostate cancer.
Oncotarget
; 8(67): 111225-111245, 2017 Dec 19.
Artigo
Inglês
| MEDLINE | ID: mdl-29340049