RESUMO
In this paper we present the T-SCAN technology and its use as a diagnostic tool for breast cancer detection. We show, using theoretical models with simplified geometries, that displaying planar two-dimensional maps of the currents detected at the breast's surface relate to the electric field distribution within the breast. This distribution is a manifestation of the bulk spatial inhomogeneities in the complex dielectric constant that represent the various tissue types. These differences may be used to discriminate between various pathological states. We furthermore illustrate a useful classifier, based on admittance data measured up to 2 kHz, and we argue that low frequency impedance measurements can be used successfully in breast cancer diagnosis.
Assuntos
Neoplasias da Mama/diagnóstico , Impedância Elétrica , Feminino , Humanos , Métodos , Modelos BiológicosRESUMO
The design of a holographic optical element for focusing a collimated off-axis beam to an on-axis point is described. It is designed according to a novel recursive technique in which the recording is done at a wavelength which differs from the readout. In this recursive technique the final holographic optical element is recorded by using other holograms to provide the aspheric recording wavefronts necessary for reducing the aberrations and maximizing the diffraction efficiency. The design is illustrated with an example where an f/3.0 focusing element is recorded at 514.5 nm and read out at 1064 nm. A spot size of 15microm and a diffraction efficiency of ~60% were measured.