Detalhe da pesquisa
1.
Genetic toxicology in silico protocol.
Regul Toxicol Pharmacol
; 107: 104403, 2019 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-31195068
2.
Current trends in in silico, in vitro toxicology, and safety biomarkers in early drug development.
Drug Chem Toxicol
; 42(2): 113-121, 2019 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-29161932
3.
Predictivity of dog co-culture model, primary human hepatocytes and HepG2 cells for the detection of hepatotoxic drugs in humans.
Toxicol Appl Pharmacol
; 275(1): 44-61, 2014 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-24333257
4.
Transcriptomic effects of di-(2-ethylhexyl)-phthalate in Syrian hamster embryo cells: an important role of early cytoskeleton disturbances in carcinogenesis?
BMC Genomics
; 12: 524, 2011 Oct 25.
Artigo
Inglês
| MEDLINE | ID: mdl-22026506
5.
Determination of phospholipidosis potential based on gene expression analysis in HepG2 cells.
Toxicol Sci
; 96(1): 101-14, 2007 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-17175557
6.
The random amplified polymorphic DNA (RAPD) assay and related techniques applied to genotoxicity and carcinogenesis studies: a critical review.
Mutat Res
; 613(2-3): 76-102, 2006.
Artigo
Inglês
| MEDLINE | ID: mdl-16979375
7.
Key Challenges and Opportunities Associated with the Use of In Vitro Models to Detect Human DILI: Integrated Risk Assessment and Mitigation Plans.
Biomed Res Int
; 2016: 9737920, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-27689095
8.
Genotoxic, cytotoxic, developmental and survival effects of tritiated water in the early life stages of the marine mollusc, Mytilus edulis.
Aquat Toxicol
; 74(3): 205-17, 2005 Sep 10.
Artigo
Inglês
| MEDLINE | ID: mdl-16043242
9.
Use of a low-density microarray for studying gene expression patterns induced by hepatotoxicants on primary cultures of rat hepatocytes.
Toxicol Sci
; 75(2): 378-92, 2003 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-12883083
10.
The random amplified polymorphic DNA (RAPD) assay to determine DNA alterations, repair and transgenerational effects in B(a)P exposed Daphnia magna.
Mutat Res
; 552(1-2): 125-40, 2004 Aug 18.
Artigo
Inglês
| MEDLINE | ID: mdl-15288546
11.
Evaluation of the random amplified polymorphic DNA (RAPD) assay for the detection of DNA damage and mutations.
Mutat Res
; 521(1-2): 151-63, 2002 Nov 26.
Artigo
Inglês
| MEDLINE | ID: mdl-12438012
12.
4-n-Nonylphenol and 17-beta estradiol may induce common DNA effects in developing barnacle larvae.
Environ Pollut
; 120(3): 735-8, 2002.
Artigo
Inglês
| MEDLINE | ID: mdl-12442797
13.
Evaluation of impedance-based label-free technology as a tool for pharmacology and toxicology investigations.
Biosensors (Basel)
; 3(1): 132-56, 2013 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-25587404
14.
Multiplexing cell viability assays.
Methods Mol Biol
; 740: 91-101, 2011.
Artigo
Inglês
| MEDLINE | ID: mdl-21468971
15.
The use of real-time cell analyzer technology in drug discovery: defining optimal cell culture conditions and assay reproducibility with different adherent cellular models.
J Biomol Screen
; 16(6): 575-87, 2011 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-21518825
16.
Phenyl-oxazoles, a new family of inverse agonists at the H(3) histamine receptor.
ChemMedChem
; 5(2): 206-12, 2010 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20043314
17.
Qualitative assessment of genotoxicity using random amplified polymorphic DNA: Comparison of genomic template stability with key fitness parameters in Daphnia magna exposed to benzo[a]pyrene.
Environ Toxicol Chem
; 18(10): 2275-2282, 1999 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-29857629
18.
Use of the random amplified polymorphic DNA (RAPD) assay for the detection of DNA damage and mutations: possible implications of confounding factors.
Biomarkers
; 7(1): 94-101, 2002.
Artigo
Inglês
| MEDLINE | ID: mdl-12101788